FOXA1 forkhead box A1 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: FOXA1provided by VGNC
Official Full Name: forkhead box A1provided by VGNC
Primary source: VGNC:VGNC:53490
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	8	NC_051812.1 (16196019..16201769, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	8	NC_006590.4 (15876271..15882016, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	8	NC_049229.1 (16245465..16251213, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	8	NC_049268.1 (15890156..15895900, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	8	NC_049749.1 (15954899..15960633, complement)

Chromosome 8 - NC_051812.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

HNF3A (e-PCR)
- UniSTS:266228

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein domain specific binding	IEA Inferred from Electronic Annotation more info	PubMed
enables transcription factor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in anatomical structure morphogenesis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: hepatocyte nuclear factor 3-alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051812.1 Reference ROS_Cfam_1.0

Range

16196019..16201769 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038673479.1 → XP_038529407.1 hepatocyte nuclear factor 3-alpha

UniProtKB/TrEMBL

A0A8C0M0J9, A0A8I3MR68

Conserved Domains (3) summary

pfam08430
Location:17 → 169

Forkhead_N; Forkhead N-terminal region

pfam09354
Location:406 → 469

HNF_C; HNF3 C-terminal domain

cd20038
Location:157 → 268

FH_FOXA1; Forkhead (FH) domain found in Forkhead box protein A1 (FOXA1) and similar proteins

Alternate UMICH_Zoey_3.1

Genomic

NC_049268.1 Alternate UMICH_Zoey_3.1

Range

15890156..15895900 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038483099.1 → XP_038339027.1 hepatocyte nuclear factor 3-alpha

Conserved Domains (3) summary

pfam08430
Location:17 → 169

Forkhead_N; Forkhead N-terminal region

pfam09354
Location:405 → 468

HNF_C; HNF3 C-terminal domain

cd20038
Location:157 → 268

FH_FOXA1; Forkhead (FH) domain found in Forkhead box protein A1 (FOXA1) and similar proteins

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049749.1 Alternate UNSW_CanFamBas_1.0

Range

15954899..15960633 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038608669.1 → XP_038464597.1 hepatocyte nuclear factor 3-alpha

Conserved Domains (3) summary

pfam08430
Location:17 → 169

Forkhead_N; Forkhead N-terminal region

pfam09354
Location:405 → 468

HNF_C; HNF3 C-terminal domain

cd20038
Location:157 → 268

FH_FOXA1; Forkhead (FH) domain found in Forkhead box protein A1 (FOXA1) and similar proteins

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049229.1 Alternate UU_Cfam_GSD_1.0

Range

16245465..16251213 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038544550.1 → XP_038400478.1 hepatocyte nuclear factor 3-alpha

UniProtKB/TrEMBL

A0A8C0M0J9, A0A8I3MR68

Conserved Domains (3) summary

pfam08430
Location:17 → 169

Forkhead_N; Forkhead N-terminal region

pfam09354
Location:406 → 469

HNF_C; HNF3 C-terminal domain

cd20038
Location:157 → 268

FH_FOXA1; Forkhead (FH) domain found in Forkhead box protein A1 (FOXA1) and similar proteins

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

15876271..15882016 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_847261.5 → XP_852354.3 hepatocyte nuclear factor 3-alpha

UniProtKB/TrEMBL

A0A8C0LDP2, A0A8C0PJM7, A0A8P0NFQ0

Conserved Domains (3) summary

pfam08430
Location:17 → 169

Forkhead_N; Forkhead N-terminal region

pfam09354
Location:405 → 468

HNF_C; HNF3 C-terminal domain

cd20038
Location:157 → 268

FH_FOXA1; Forkhead (FH) domain found in Forkhead box protein A1 (FOXA1) and similar proteins