rnf130 ring finger protein 130 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rnf130provided by ZNC
Official Full Name: ring finger protein 130provided by ZNC
Primary source: ZFIN:ZDB-GENE-050522-525
See related: Ensembl:ENSDARG00000089767 AllianceGenome:ZFIN:ZDB-GENE-050522-525
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fc14g02; zgc:113271
Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm. Orthologous to human RNF130 (ring finger protein 130). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (36765614..36863454, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (36425300..36523129, complement)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fc14g02.x1 (e-PCR)
- UniSTS:203814

G40211 (e-PCR)
- UniSTS:77970

fc88b05.x1 (e-PCR)
- UniSTS:194728

G45639 (e-PCR)
- UniSTS:106441

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables ubiquitin protein ligase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: E3 ubiquitin-protein ligase RNF130

Names: goliath

NP_001018301.1

EC 2.3.2.27

XP_009289393.1

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001020465.1 → NP_001018301.1 E3 ubiquitin-protein ligase RNF130

See identical proteins and their annotated locations for NP_001018301.1

Status: PROVISIONAL

Source sequence(s)

BC095880

UniProtKB/TrEMBL

A0A8N7XJ76, B2GPU6, E7FCE1, Q501T3

Related

ENSDARP00000134816.1, ENSDART00000158052.3

Conserved Domains (2) summary

cd02122
Location:13 → 152

PA_GRAIL_like; PA _GRAIL_like: Protease-associated (PA) domain GRAIL-like. This group includes PA domain containing E3 (ubiquitin ligases) similar to human GRAIL (gene related to anergy in lymphocytes) protein. Proteins in this group contain a C3H2C3 RING finger. E3 ...

pfam13639
Location:235 → 278

zf-RING_2; Ring finger domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007125.7 Reference GRCz11 Primary Assembly

Range

36765614..36863454 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009291118.3 → XP_009289393.1 E3 ubiquitin-protein ligase RNF130 isoform X1

UniProtKB/TrEMBL

A0A8M3B0D3

Conserved Domains (2) summary

cd02122
Location:49 → 188

PA_GRAIL_like; PA _GRAIL_like: Protease-associated (PA) domain GRAIL-like. This group includes PA domain containing E3 (ubiquitin ligases) similar to human GRAIL (gene related to anergy in lymphocytes) protein. Proteins in this group contain a C3H2C3 RING finger. E3 ...

pfam13639
Location:271 → 314

zf-RING_2; Ring finger domain