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LEMD3 LEM domain containing 3 [ Canis lupus familiaris (dog) ]

Gene ID: 608380, updated on 5-Mar-2024

Summary

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Official Symbol
LEMD3provided by VGNC
Official Full Name
LEM domain containing 3provided by VGNC
Primary source
VGNC:VGNC:42633
See related
Ensembl:ENSCAFG00845012211
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See LEMD3 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 10 NC_051814.1 (7887012..7959867)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 10 NC_006592.4 (7711419..7784249)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 10 NC_049231.1 (8135524..8208304)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 10 NC_049270.1 (7763790..7836639)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 10 NC_049751.1 (8003513..8063233)

Chromosome 10 - NC_051814.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119873584 Neighboring gene WNT inhibitory factor 1 Neighboring gene uncharacterized LOC102157003 Neighboring gene methionine sulfoxide reductase B3 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC111097584

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chromatin DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nuclear envelope organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nuclear inner membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: inner nuclear membrane protein Man1; inner nuclear membrane protein Man1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051814.1 Reference ROS_Cfam_1.0

    Range
    7887012..7959867
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038679256.1 → XP_038535184.1  inner nuclear membrane protein Man1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TBY2, A0A8I3RWY7
    Related
    ENSCAFP00845017079.1, ENSCAFT00845021719.1
    Conserved Domains (3) summary
    pfam09402
    Location:559 → 771
    MSC; Man1-Src1p-C-terminal domain
    cd12286
    Location:808 → 899
    RRM_Man1; RNA recognition motif (RRM) found in inner nuclear membrane protein Man1 (Man1) and similar proteins
    cl02649
    Location:12 → 50
    LEM; LEM (Lap2/Emerin/Man1) domain found in emerin, lamina-associated polypeptide 2 (LAP2), inner nuclear membrane protein Man1 and similar proteins

RNA

  1. XR_005433128.1 RNA Sequence

  2. XR_005433127.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049270.1 Alternate UMICH_Zoey_3.1

    Range
    7763790..7836639
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038488033.1 → XP_038343961.1  inner nuclear membrane protein Man1 isoform X1

RNA

  1. XR_005331641.1 RNA Sequence

  2. XR_005331640.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049751.1 Alternate UNSW_CanFamBas_1.0

    Range
    8003513..8063233
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038613447.1 → XP_038469375.1  LOW QUALITY PROTEIN: inner nuclear membrane protein Man1 isoform X2

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049231.1 Alternate UU_Cfam_GSD_1.0

    Range
    8135524..8208304
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038549927.1 → XP_038405855.1  inner nuclear membrane protein Man1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TBY2

RNA

  1. XR_005365346.1 RNA Sequence

  2. XR_005365345.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    7711419..7784249
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022424879.2 → XP_022280587.2  inner nuclear membrane protein Man1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TBY2
    Conserved Domains (3) summary
    pfam09402
    Location:555 → 767
    MSC; Man1-Src1p-C-terminal domain
    cd12286
    Location:804 → 895
    RRM_Man1; RNA recognition motif (RRM) found in inner nuclear membrane protein Man1 (Man1) and similar proteins
    cl02649
    Location:13 → 51
    LEM; LEM (Lap2/Emerin/Man1) domain found in emerin, lamina-associated polypeptide 2 (LAP2), inner nuclear membrane protein Man1 and similar proteins

RNA

  1. XR_005410786.1 RNA Sequence

  2. XR_005410784.1 RNA Sequence

Nucleotide Protein
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