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NPR3 natriuretic peptide receptor 3 [ Canis lupus familiaris (dog) ]

Gene ID: 612616, updated on 5-Mar-2024

Summary

Official Symbol
NPR3provided by VGNC
Official Full Name
natriuretic peptide receptor 3provided by VGNC
Primary source
VGNC:VGNC:58320
See related
Ensembl:ENSCAFG00845001703
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

See NPR3 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 4 NC_051808.1 (75311739..75380568, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 4 NC_006586.4 (74429055..74497877, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 4 NC_049225.1 (75708336..75777195, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 4 NC_049264.1 (75049009..75118047, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 4 NC_049745.1 (75177562..75246355, complement)

Chromosome 4 - NC_051808.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111095653 Neighboring gene U4 spliceosomal RNA Neighboring gene uncharacterized LOC111095652 Neighboring gene uncharacterized LOC119871575 Neighboring gene SUB1 regulator of transcription

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables natriuretic peptide receptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables peptide hormone binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of blood pressure IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in vasodilation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
atrial natriuretic peptide receptor 3
Names
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051808.1 Reference ROS_Cfam_1.0

    Range
    75311739..75380568 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038663984.1XP_038519912.1  atrial natriuretic peptide receptor 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SGJ1, A0A8I3MJ47
    Conserved Domains (2) summary
    cd12841
    Location:468503
    TM_EphA1; Transmembrane domain of Ephrin Receptor A1 Protein Tyrosine Kinase
    cd06386
    Location:48443
    PBP1_NPR_C; ligand-binding domain of type C natriuretic peptide receptor
  2. XM_038663983.1XP_038519911.1  atrial natriuretic peptide receptor 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0SGJ1, A0A8C0YX94, A0A8I3MJ47, A0A8I3RQ58
    Related
    ENSCAFP00845002401.1, ENSCAFT00845003010.1
    Conserved Domains (2) summary
    cd12841
    Location:473504
    TM_EphA1; Transmembrane domain of Ephrin Receptor A1 Protein Tyrosine Kinase
    cd06386
    Location:48443
    PBP1_NPR_C; ligand-binding domain of type C natriuretic peptide receptor

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049264.1 Alternate UMICH_Zoey_3.1

    Range
    75049009..75118047 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038474269.1XP_038330197.1  atrial natriuretic peptide receptor 3 isoform X2

    Conserved Domains (2) summary
    cd12841
    Location:468503
    TM_EphA1; Transmembrane domain of Ephrin Receptor A1 Protein Tyrosine Kinase
    cd06386
    Location:48443
    PBP1_NPR_C; ligand-binding domain of type C natriuretic peptide receptor
  2. XM_038474268.1XP_038330196.1  atrial natriuretic peptide receptor 3 isoform X1

    Conserved Domains (2) summary
    cd12841
    Location:473504
    TM_EphA1; Transmembrane domain of Ephrin Receptor A1 Protein Tyrosine Kinase
    cd06386
    Location:48443
    PBP1_NPR_C; ligand-binding domain of type C natriuretic peptide receptor

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049745.1 Alternate UNSW_CanFamBas_1.0

    Range
    75177562..75246355 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038599671.1XP_038455599.1  atrial natriuretic peptide receptor 3 isoform X2

    Conserved Domains (2) summary
    cd12841
    Location:468503
    TM_EphA1; Transmembrane domain of Ephrin Receptor A1 Protein Tyrosine Kinase
    cd06386
    Location:48443
    PBP1_NPR_C; ligand-binding domain of type C natriuretic peptide receptor
  2. XM_038599670.1XP_038455598.1  atrial natriuretic peptide receptor 3 isoform X1

    Conserved Domains (2) summary
    cd12841
    Location:473504
    TM_EphA1; Transmembrane domain of Ephrin Receptor A1 Protein Tyrosine Kinase
    cd06386
    Location:48443
    PBP1_NPR_C; ligand-binding domain of type C natriuretic peptide receptor

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049225.1 Alternate UU_Cfam_GSD_1.0

    Range
    75708336..75777195 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038535397.1XP_038391325.1  atrial natriuretic peptide receptor 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SGJ1, A0A8I3MJ47
  2. XM_038535396.1XP_038391324.1  atrial natriuretic peptide receptor 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0SGJ1, A0A8I3MJ47

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    74429055..74497877 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038500471.1XP_038356399.1  atrial natriuretic peptide receptor 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SGJ1, A0A8I3MJ47
    Conserved Domains (2) summary
    cd12841
    Location:468503
    TM_EphA1; Transmembrane domain of Ephrin Receptor A1 Protein Tyrosine Kinase
    cd06386
    Location:48443
    PBP1_NPR_C; ligand-binding domain of type C natriuretic peptide receptor
  2. XM_038500469.1XP_038356397.1  atrial natriuretic peptide receptor 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0SGJ1, A0A8C0YX94, A0A8I3MJ47, A0A8I3RQ58
    Conserved Domains (2) summary
    cd12841
    Location:473504
    TM_EphA1; Transmembrane domain of Ephrin Receptor A1 Protein Tyrosine Kinase
    cd06386
    Location:48443
    PBP1_NPR_C; ligand-binding domain of type C natriuretic peptide receptor