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DNAH12 dynein axonemal heavy chain 12 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 703670, updated on 5-Mar-2024

Summary

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Gene symbol
DNAH12
Gene description
dynein axonemal heavy chain 12
See related
Ensembl:ENSMMUG00000054683
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See DNAH12 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
77
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (113452229..113697607, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (84600713..84838867)

Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene cytochrome c-like Neighboring gene HESX homeobox 1 Neighboring gene adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 Neighboring gene interferon-stimulated 20 kDa exonuclease-like 2 pseudogene Neighboring gene ankyrin repeat and SOCS box containing 14 Neighboring gene elongation factor 1-alpha 1 pseudogene Neighboring gene small nucleolar RNA U13 Neighboring gene U6 spliceosomal RNA Neighboring gene RING-box protein 2 pseudogene Neighboring gene 40S ribosomal protein S8 pseudogene Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene phosphodiesterase 12 Neighboring gene ADP ribosylation factor 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables dynein intermediate chain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables dynein light intermediate chain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables minus-end-directed microtubule motor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in microtubule-based movement IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of dynein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dynein heavy chain 12, axonemal

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041755.1 Reference Mmul_10 Primary Assembly

    Range
    113452229..113697607 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015130629.2 → XP_014986115.1  dynein heavy chain 12, axonemal isoform X1

    UniProtKB/TrEMBL
    F6PY57
    Conserved Domains (5) summary
    pfam03028
    Location:3251 → 3948
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam08393
    Location:679 → 1110
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12777
    Location:2519 → 2859
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:2896 → 3110
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:1238 → 1468
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  2. XM_015130630.2 → XP_014986116.1  dynein heavy chain 12, axonemal isoform X2

    Conserved Domains (5) summary
    pfam03028
    Location:3167 → 3864
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam08393
    Location:595 → 1026
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12777
    Location:2435 → 2775
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:2812 → 3026
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:1154 → 1384
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  3. XM_015130631.2 → XP_014986117.1  dynein heavy chain 12, axonemal isoform X3

    UniProtKB/TrEMBL
    F6PY14, G7ML05
    Related
    ENSMMUP00000020095.4, ENSMMUT00000021486.4
Nucleotide Protein
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