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CIITA class II major histocompatibility complex transactivator [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 710761, updated on 5-Mar-2024

Summary

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Official Symbol
CIITAprovided by VGNC
Official Full Name
class II major histocompatibility complex transactivatorprovided by VGNC
Primary source
VGNC:VGNC:71385
See related
Ensembl:ENSMMUG00000007777
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 20
Exon count:
23
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (10827489..10889183)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (10920213..10972399)

Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene NUBP iron-sulfur cluster assembly factor 1, cytosolic Neighboring gene trans-golgi network vesicle protein 23 homolog A Neighboring gene rho GTPase-activating protein 21-like Neighboring gene C-type lectin domain containing 16A Neighboring gene Dexi homolog Neighboring gene uncharacterized LOC114674400

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MHC class I biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MHC class II biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
MHC class II transactivator
XP_014981098.2
XP_014981099.2
XP_014981100.2
XP_014981101.2
XP_014981102.2
XP_028697126.1
XP_028697127.1
XP_028697128.1
XP_028697129.1
XP_028697130.1
XP_028697131.1
XP_028697132.1
XP_028697134.1
XP_028697135.1
XP_028697136.1
XP_028697137.1
XP_028697138.1
XP_028697139.1
XP_028697140.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041773.1 Reference Mmul_10 Primary Assembly

    Range
    10827489..10889183
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028841293.1 → XP_028697126.1  MHC class II transactivator isoform X1

    UniProtKB/TrEMBL
    F6S719
    Conserved Domains (3) summary
    cd00116
    Location:867 → 1192
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:1064 → 1091
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:493 → 661
    NACHT; NACHT domain

  2. XM_028841295.1 → XP_028697128.1  MHC class II transactivator isoform X3

    UniProtKB/TrEMBL
    F6S719
    Conserved Domains (2) summary
    cd00116
    Location:867 → 1161
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    pfam05729
    Location:493 → 661
    NACHT; NACHT domain

  3. XM_028841297.1 → XP_028697130.1  MHC class II transactivator isoform X5

    UniProtKB/TrEMBL
    F6S719
    Conserved Domains (3) summary
    cd00116
    Location:818 → 1143
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:1015 → 1042
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:444 → 612
    NACHT; NACHT domain

  4. XM_028841294.1 → XP_028697127.1  MHC class II transactivator isoform X2

    UniProtKB/TrEMBL
    A0A5F8A5T1, F6S719
    Related
    ENSMMUP00000073242.1, ENSMMUT00000084454.1
    Conserved Domains (3) summary
    cd00116
    Location:866 → 1191
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:1063 → 1090
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:492 → 660
    NACHT; NACHT domain

  5. XM_028841298.1 → XP_028697131.1  MHC class II transactivator isoform X6

    UniProtKB/TrEMBL
    F6S719
    Conserved Domains (3) summary
    cd00116
    Location:817 → 1142
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:1014 → 1041
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:443 → 611
    NACHT; NACHT domain

  6. XM_028841296.1 → XP_028697129.1  MHC class II transactivator isoform X4

    UniProtKB/TrEMBL
    F6S719
    Conserved Domains (3) summary
    cd00116
    Location:819 → 1144
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:1016 → 1043
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:445 → 613
    NACHT; NACHT domain

  7. XM_028841302.1 → XP_028697135.1  MHC class II transactivator isoform X13

    UniProtKB/TrEMBL
    F6S719
    Conserved Domains (3) summary
    cd00116
    Location:770 → 1095
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:967 → 994
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:396 → 564
    NACHT; NACHT domain

  8. XM_028841306.1 → XP_028697139.1  MHC class II transactivator isoform X18

    UniProtKB/TrEMBL
    A0A5F7ZXQ8
    Related
    ENSMMUP00000069427.1, ENSMMUT00000088761.1
    Conserved Domains (3) summary
    cd00116
    Location:741 → 1066
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:938 → 965
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:367 → 535
    NACHT; NACHT domain

  9. XM_028841305.1 → XP_028697138.1  MHC class II transactivator isoform X17

    UniProtKB/TrEMBL
    A0A1D5RDM2, A0A1D5RFJ5
    Related
    ENSMMUP00000058415.2, ENSMMUT00000067056.2
    Conserved Domains (3) summary
    cd00116
    Location:742 → 1067
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:939 → 966
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:368 → 536
    NACHT; NACHT domain

  10. XM_028841301.1 → XP_028697134.1  MHC class II transactivator isoform X12

    UniProtKB/TrEMBL
    A0A5F7ZNK3, H9Z940
    Related
    ENSMMUP00000059089.2, ENSMMUT00000058326.2
    Conserved Domains (3) summary
    cd00116
    Location:789 → 1114
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:986 → 1013
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:415 → 583
    NACHT; NACHT domain

  11. XM_028841299.1 → XP_028697132.1  MHC class II transactivator isoform X10

    UniProtKB/TrEMBL
    H9Z940
    Related
    ENSMMUP00000032638.2, ENSMMUT00000039568.3
    Conserved Domains (3) summary
    cd00116
    Location:790 → 1115
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:987 → 1014
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:416 → 584
    NACHT; NACHT domain

  12. XM_028841304.1 → XP_028697137.1  MHC class II transactivator isoform X16

    UniProtKB/TrEMBL
    A0A1D5RDM2, A0A1D5RFJ5
    Conserved Domains (3) summary
    cd00116
    Location:742 → 1067
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:939 → 966
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:368 → 536
    NACHT; NACHT domain

  13. XM_015125614.2 → XP_014981100.2  MHC class II transactivator isoform X9

    UniProtKB/TrEMBL
    H9Z940
    Conserved Domains (3) summary
    cd00116
    Location:790 → 1115
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:987 → 1014
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:416 → 584
    NACHT; NACHT domain

  14. XM_015125615.2 → XP_014981101.2  MHC class II transactivator isoform X11

    UniProtKB/TrEMBL
    A0A5F7ZNK3, H9Z940
    Related
    ENSMMUP00000067219.1, ENSMMUT00000091622.1
    Conserved Domains (3) summary
    cd00116
    Location:789 → 1114
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:986 → 1013
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:415 → 583
    NACHT; NACHT domain

  15. XM_015125612.2 → XP_014981098.2  MHC class II transactivator isoform X7

    UniProtKB/TrEMBL
    H9Z940
    Conserved Domains (3) summary
    cd00116
    Location:805 → 1130
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:1002 → 1029
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:431 → 599
    NACHT; NACHT domain

  16. XM_015125613.2 → XP_014981099.2  MHC class II transactivator isoform X8

    UniProtKB/TrEMBL
    H9Z940
    Conserved Domains (3) summary
    cd00116
    Location:804 → 1129
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:1001 → 1028
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:430 → 598
    NACHT; NACHT domain

  17. XM_028841307.1 → XP_028697140.1  MHC class II transactivator isoform X19

    UniProtKB/TrEMBL
    A0A5F7ZXQ8
    Conserved Domains (3) summary
    cd00116
    Location:718 → 1043
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:915 → 942
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:344 → 512
    NACHT; NACHT domain

  18. XM_015125616.2 → XP_014981102.2  MHC class II transactivator isoform X14

    UniProtKB/TrEMBL
    H9Z940
    Conserved Domains (3) summary
    cd00116
    Location:766 → 1091
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:963 → 990
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:392 → 560
    NACHT; NACHT domain

  19. XM_028841303.1 → XP_028697136.1  MHC class II transactivator isoform X15

    UniProtKB/TrEMBL
    H9Z940
    Conserved Domains (3) summary
    cd00116
    Location:765 → 1090
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:962 → 989
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:391 → 559
    NACHT; NACHT domain
Nucleotide Protein
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