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TEX1 Tex1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855468, updated on 17-May-2024

Summary

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Gene symbol
TEX1
Gene description
Tex1p
Primary source
FungiDB:YNL253W
Locus tag
YNL253W
See related
SGD:S000005197; AllianceGenome:SGD:S000005197; VEuPathDB:YNL253W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables mRNA binding activity. Predicted to be involved in mRNA export from nucleus. Part of transcription export complex. Orthologous to human THOC3 (THO complex 3). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See TEX1 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (170018..171286)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene mRNA-binding translational activator GIS2 Neighboring gene Rtc4p Neighboring gene mitochondrial 54S ribosomal protein YmL17/YmL30 Neighboring gene Nrd1 complex RNA-binding subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural characterization of the Saccharomyces cerevisiae THO complex by small-angle X-ray scattering. Poulsen JB, et al. PLoS One, 2014. PMID 25062267, Free PMC Article
  2. Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor. Peña A, et al. EMBO J, 2012 Mar 21. PMID 22314234, Free PMC Article
  3. Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex. Schuller SK, et al. Elife, 2020 Nov 16. PMID 33191913, Free PMC Article
  4. Cryo-EM structure of the yeast TREX complex and coordination with the SR-like protein Gbp2. Xie Y, et al. Elife, 2021 Mar 31. PMID 33787496, Free PMC Article
  5. A yeast model for polyalanine-expansion aggregation and toxicity. Konopka CA, et al. Mol Biol Cell, 2011 Jun 15. PMID 21508314, Free PMC Article

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables mRNA binding HDA PubMed 
Process Evidence Code Pubs
involved_in mRNA export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mRNA export from nucleus IC
Inferred by Curator
more info
 PubMed 
involved_in mRNA export from nucleus IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of THO complex part of transcription export complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of transcription export complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Tex1p
NP_014146.1
  • Protein involved in mRNA export; component of the transcription export (TREX) complex

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    170018..171286
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183091.1 → NP_014146.1  TPA: Tex1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014146.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W0U0, P53851
    UniProtKB/TrEMBL
    A0A8H4BWV2, A6ZRJ0, B3LP97, C7GPA8, N1P517
    Conserved Domains (2) summary
    COG2319
    Location:1 → 374
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:66 → 109
    7WD40; WD40 repeat [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53851.1

Gene LinkOut

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