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    Sv2b synaptic vesicle glycoprotein 2 b [ Mus musculus (house mouse) ]

    Gene ID: 64176, updated on 23-Jun-2021

    Summary

    Official Symbol
    Sv2bprovided by MGI
    Official Full Name
    synaptic vesicle glycoprotein 2 bprovided by MGI
    Primary source
    MGI:MGI:1927338
    See related
    Ensembl:ENSMUSG00000053025
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI850768; mKIAA0735; A830038F04Rik
    Expression
    Biased expression in cortex adult (RPKM 34.7), frontal lobe adult (RPKM 26.9) and 2 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Sv2b in Genome Data Viewer
    Location:
    7; 7 D1
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (74764642..74959143, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (75114894..75309262, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (82259780..82454148, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53361 Neighboring gene RIKEN cDNA 4930533N22 gene Neighboring gene RIKEN cDNA 1500012K07 gene Neighboring gene ribosomal protein S28 pseudogene Neighboring gene predicted gene, 46017

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC38746

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within chemical synaptic transmission TAS
    Traceable Author Statement
    more info
    PubMed 
    acts_upstream_of_or_within neurotransmitter transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in integral component of membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of synaptic vesicle membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
     
    located_in synaptic vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in synaptic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in synaptic vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    synaptic vesicle glycoprotein 2B
    Names
    synaptic vesicle protein 2B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109753.1NP_001103223.1  synaptic vesicle glycoprotein 2B

      See identical proteins and their annotated locations for NP_001103223.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 3. All seven variants encode the same protein.
      Source sequence(s)
      AK043830, AK147261, BC060224, BY269935
      Consensus CDS
      CCDS21368.1
      UniProtKB/Swiss-Prot
      Q8BG39
      Related
      ENSMUSP00000082254.6, ENSMUST00000085164.7
      Conserved Domains (1) summary
      TIGR01299
      Location:8683
      synapt_SV2; synaptic vesicle protein SV2
    2. NM_001360571.1NP_001347500.1  synaptic vesicle glycoprotein 2B

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) represents the longest transcript. All seven variants encode the same protein.
      Source sequence(s)
      AC113471, AC116898, AC127355
      Consensus CDS
      CCDS21368.1
      Conserved Domains (1) summary
      TIGR01299
      Location:8683
      synapt_SV2; synaptic vesicle protein SV2
    3. NM_001360572.1NP_001347501.1  synaptic vesicle glycoprotein 2B

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 3. All seven variants encode the same protein.
      Source sequence(s)
      AC113471, AC116898, AC127355
      Consensus CDS
      CCDS21368.1
      Conserved Domains (1) summary
      TIGR01299
      Location:8683
      synapt_SV2; synaptic vesicle protein SV2
    4. NM_001360573.1NP_001347502.1  synaptic vesicle glycoprotein 2B

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 3. All seven variants encode the same protein.
      Source sequence(s)
      AC113471, AC116898, AC127355
      Consensus CDS
      CCDS21368.1
      Conserved Domains (1) summary
      TIGR01299
      Location:8683
      synapt_SV2; synaptic vesicle protein SV2
    5. NM_001360574.1NP_001347503.1  synaptic vesicle glycoprotein 2B

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 3. All seven variants encode the same protein.
      Source sequence(s)
      AC113471, AC116898, AC127355
      Consensus CDS
      CCDS21368.1
      Conserved Domains (1) summary
      TIGR01299
      Location:8683
      synapt_SV2; synaptic vesicle protein SV2
    6. NM_001360575.1NP_001347504.1  synaptic vesicle glycoprotein 2B

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 3. All seven variants encode the same protein.
      Source sequence(s)
      AC116898, AK029736, BC060224
      Consensus CDS
      CCDS21368.1
      Related
      ENSMUSP00000146049.2, ENSMUST00000206344.2
      Conserved Domains (1) summary
      TIGR01299
      Location:8683
      synapt_SV2; synaptic vesicle protein SV2
    7. NM_153579.4NP_705807.2  synaptic vesicle glycoprotein 2B

      See identical proteins and their annotated locations for NP_705807.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 3. All seven variants encode the same protein.
      Source sequence(s)
      BC060224, BC079568
      Consensus CDS
      CCDS21368.1
      UniProtKB/Swiss-Prot
      Q8BG39
      Related
      ENSMUSP00000127245.2, ENSMUST00000165175.8
      Conserved Domains (1) summary
      TIGR01299
      Location:8683
      synapt_SV2; synaptic vesicle protein SV2

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      74764642..74959143 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036153323.1XP_036009216.1  synaptic vesicle glycoprotein 2B isoform X1

      Conserved Domains (1) summary
      TIGR01299
      Location:8683
      synapt_SV2; synaptic vesicle protein SV2
    2. XM_036153324.1XP_036009217.1  synaptic vesicle glycoprotein 2B isoform X1

      Conserved Domains (1) summary
      TIGR01299
      Location:8683
      synapt_SV2; synaptic vesicle protein SV2
    3. XM_006541059.4XP_006541122.1  synaptic vesicle glycoprotein 2B isoform X1

      See identical proteins and their annotated locations for XP_006541122.1

      UniProtKB/Swiss-Prot
      Q8BG39
      Conserved Domains (1) summary
      TIGR01299
      Location:8683
      synapt_SV2; synaptic vesicle protein SV2
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