U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ankrd27 ankyrin repeat domain 27 (VPS9 domain) [ Danio rerio (zebrafish) ]

    Gene ID: 386887, updated on 27-Mar-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ankrd27provided by ZNC
    Official Full Name
    ankyrin repeat domain 27 (VPS9 domain)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-121105-1
    See related
    Ensembl:ENSDARG00000089207 AllianceGenome:ZFIN:ZDB-GENE-121105-1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc41e04; wu:fc41e04; si:ch211-113a14.30
    Summary
    Predicted to enable SNARE binding activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in early endosome to late endosome transport and neuron projection morphogenesis. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasmic vesicle; neuron projection; and plasma membrane. Human ortholog(s) of this gene implicated in eosinophilic esophagitis. Orthologous to human ANKRD27 (ankyrin repeat domain 27). [provided by Alliance of Genome Resources, Apr 2022]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ankrd27 in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (36404130..36438571)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (35854389..35878884)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene si:ch211-113a14.28 Neighboring gene uncharacterized LOC103909891 Neighboring gene iroquois homeobox 3b Neighboring gene uncharacterized LOC110438397

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables SNARE binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables guanyl-nucleotide exchange factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in early endosome to late endosome transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in neuron projection morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in early endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in late endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in tubular endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    ankyrin repeat domain-containing protein 27

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      36404130..36438571
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021470748.1 → XP_021326423.1  ankyrin repeat domain-containing protein 27 isoform X3

      UniProtKB/TrEMBL
      A0A8M9PHH9
      Related
      ENSDARP00000110301.3, ENSDART00000124347.3
      Conserved Domains (4) summary
      cd00204
      Location:736 → 861
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:741 → 772
      ANK; ANK repeat [structural motif]
      cl19569
      Location:265 → 366
      VPS9; Vacuolar sorting protein 9 (VPS9) domain
      cl26073
      Location:566 → 895
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_021470747.1 → XP_021326422.1  ankyrin repeat domain-containing protein 27 isoform X3

      UniProtKB/TrEMBL
      A0A8M9PHH9
      Conserved Domains (4) summary
      cd00204
      Location:736 → 861
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:741 → 772
      ANK; ANK repeat [structural motif]
      cl19569
      Location:265 → 366
      VPS9; Vacuolar sorting protein 9 (VPS9) domain
      cl26073
      Location:566 → 895
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_021470749.1 → XP_021326424.1  ankyrin repeat domain-containing protein 27 isoform X4

      UniProtKB/TrEMBL
      A0A8M9PNG5
      Conserved Domains (4) summary
      cd00204
      Location:735 → 860
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:740 → 771
      ANK; ANK repeat [structural motif]
      cl19569
      Location:264 → 365
      VPS9; Vacuolar sorting protein 9 (VPS9) domain
      cl26073
      Location:565 → 894
      Ank_2; Ankyrin repeats (3 copies)

    4. XM_021470745.1 → XP_021326420.1  ankyrin repeat domain-containing protein 27 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PZ85
      Conserved Domains (4) summary
      cd00204
      Location:773 → 898
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:778 → 809
      ANK; ANK repeat [structural motif]
      cl19569
      Location:302 → 403
      VPS9; Vacuolar sorting protein 9 (VPS9) domain
      cl26073
      Location:603 → 932
      Ank_2; Ankyrin repeats (3 copies)

    5. XM_021470746.1 → XP_021326421.1  ankyrin repeat domain-containing protein 27 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PVP7
      Conserved Domains (4) summary
      cd00204
      Location:772 → 897
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:777 → 808
      ANK; ANK repeat [structural motif]
      cl19569
      Location:301 → 402
      VPS9; Vacuolar sorting protein 9 (VPS9) domain
      cl26073
      Location:602 → 931
      Ank_2; Ankyrin repeats (3 copies)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous