Slmap sarcolemma associated protein [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Slmapprovided by MGI
Official Full Name: sarcolemma associated proteinprovided by MGI
Primary source: MGI:MGI:1933549
See related: Ensembl:ENSMUSG00000021870 AllianceGenome:MGI:1933549
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Slap; Miranda; mKIAA1601; D330001L02Rik
Summary: Predicted to be involved in protein localization to plasma membrane; regulation of membrane depolarization during cardiac muscle cell action potential; and regulation of voltage-gated sodium channel activity. Is integral component of membrane. Is expressed in heart. Orthologous to human SLMAP (sarcolemma associated protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in bladder adult (RPKM 44.9), adrenal adult (RPKM 22.0) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 14 A3; 14 16.09 cM

Exon count:: 26

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	14	NC_000080.7 (26134323..26256103, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	14	NC_000080.6 (26413168..26534624, complement)

Chromosome 14 - NC_000080.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Manipulation of the nuclear envelope-associated protein SLAP during mammalian brain development affects cortical lamination and exploratory behavior.
Title: Manipulation of the nuclear envelope-associated protein SLAP during mammalian brain development affects cortical lamination and exploratory behavior.
A novel role for SLMAP3 in the selective regulation of important ion transport proteins at the level of gene expression and this suggests that it may be a unique target in cardiovascular function and diseases.
Title: SLMAP3 isoform modulates cardiac gene expression and function.
These data demonstrate that SLMAP is a regulator of E-C coupling at the level of the SR and its perturbation results in progressive deterioration of cardiac electrophysiology and function.
Title: Tail-anchored membrane protein SLMAP is a novel regulator of cardiac function at the sarcoplasmic reticulum.
SLMAP may be an important regulator of glucose uptake or involved in GLUT-4 fusion/translocation into the plasma membrane of mouse abdominal adipose tissue; changes in SLMAP expression are linked to hyperglycemia and diabetes.
Title: Increased expression of the tail-anchored membrane protein SLMAP in adipose tissue from type 2 Tally Ho diabetic mice.
the genomic structure; SLMAP sequences directed a reporter green fluorescent protein (GFP) to the centrosome, and deletions of the newly identified N-terminal sequence from SLMAP prevented the centrosomal targeting
Title: A novel isoform of sarcolemmal membrane-associated protein (SLMAP) is a component of the microtubule organizing centre.
Microvasculature in db/db mice undergoes significant changes in vascular function with endothelial component of vascular dysfunction specifically correlating with overexpression of SLMAP.
Title: Endothelial dysfunction in Type 2 diabetes correlates with deregulated expression of the tail-anchored membrane protein SLMAP.
The cardiac-specific expression of SLMAP isoforms that can be targeted to distinct subcellular membranes, self assemble, and interact with the myofibril suggests a potential role in the structural arrangement of the E-C coupling apparatus.
Title: Molecular properties of cardiac tail-anchored membrane protein SLMAP are consistent with structural role in arrangement of excitation-contraction coupling apparatus.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (4)
Transposon induced (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

NoName (e-PCR)
- UniSTS:237141

MARC_17013-17014:1023291181:1 (e-PCR)
- UniSTS:268183

D14Ertd574e (e-PCR), detects polymorphism
- UniSTS:167139

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in protein localization to plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein localization to plasma membrane	ISO Inferred from Sequence Orthology more info
involved_in regulation of membrane depolarization during cardiac muscle cell action potential	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of membrane depolarization during cardiac muscle cell action potential	ISO Inferred from Sequence Orthology more info
involved_in regulation of sodium ion transmembrane transport	ISO Inferred from Sequence Orthology more info
involved_in regulation of voltage-gated sodium channel activity	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of voltage-gated sodium channel activity	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in extracellular space	IEA Inferred from Electronic Annotation more info
located_in membrane	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: sarcolemmal membrane-associated protein

Names: sarcolemmal-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001310445.1 → NP_001297374.1 sarcolemmal membrane-associated protein isoform 1

See identical proteins and their annotated locations for NP_001297374.1

Status: VALIDATED

Description

Transcript Variant: This variant (1) encodes the longest isoform (1).

Source sequence(s)

AK141597, AK164911, BP762661, DV646594, DV651439, DV655219

Consensus CDS

CCDS79284.1

UniProtKB/Swiss-Prot

Q3TLP0, Q3UIZ6, Q3URD3, Q6ZPL8, Q8VC86, Q9EQ03

UniProtKB/TrEMBL

F8WIH0

Related

ENSMUSP00000117816.2, ENSMUST00000139075.8

Conserved Domains (5) summary

COG1716
Location:46 → 109

FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

TIGR02168
Location:163 → 812

SMC_prok_B; chromosome segregation protein SMC, common bacterial type

pfam07851
Location:680 → 775

TMPIT; TMPIT-like protein

cl19219
Location:297 → 367

DUF342; Protein of unknown function (DUF342)
NM_001347494.1 → NP_001334423.1 sarcolemmal membrane-associated protein isoform 3

Status: VALIDATED

Description

Transcript Variant: This variant (3) lacks three consecutive alternate in-frame exons in the central coding region compared to variant 1. It encodes isoform 3 which has the same N- and C-termini, but is shorter, and has a single internal aa difference compared to isoform 1.

Source sequence(s)

AK141597, AK164911, BP762661, CA539668, CK619354, CO432990, DV646594, DV651439, DV655219

Consensus CDS

CCDS84099.1

UniProtKB/TrEMBL

D3Z7V3, F8WIH0

Related

ENSMUSP00000107949.2, ENSMUST00000112330.8

Conserved Domains (3) summary

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

TIGR02168
Location:163 → 757

SMC_prok_B; chromosome segregation protein SMC, common bacterial type

cd21911
Location:163 → 225

CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein
NM_032008.4 → NP_114397.3 sarcolemmal membrane-associated protein isoform 2

Status: VALIDATED

Description

Transcript Variant: This variant (2) lacks an alternate in-frame exon in the central coding region and contains an alternate exon in the 3' coding region, which results in a frameshift, compared to variant 1. It encodes isoform 2 which differs in the central region of the protein and has a distinct and shorter C-terminus compared to isoform 1.

Source sequence(s)

AK164911, BP762661, CK619354, CO432990, CX205605, DV646594, DV651439, DV655219

Consensus CDS

CCDS26880.1

UniProtKB/TrEMBL

F8WIH0

Related

ENSMUSP00000046956.4, ENSMUST00000038522.10

Conserved Domains (5) summary

COG1716
Location:46 → 109

FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

TIGR02168
Location:163 → 791

SMC_prok_B; chromosome segregation protein SMC, common bacterial type

pfam07851
Location:659 → 754

TMPIT; TMPIT-like protein

cl19219
Location:297 → 367

DUF342; Protein of unknown function (DUF342)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000080.7 Reference GRCm39 C57BL/6J

Range

26134323..26256103 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_036158935.1 → XP_036014828.1 sarcolemmal membrane-associated protein isoform X28

UniProtKB/TrEMBL

F8WIH0

Conserved Domains (3) summary

COG0419
Location:167 → 717

SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd21911
Location:163 → 225

CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein
XM_036158925.1 → XP_036014818.1 sarcolemmal membrane-associated protein isoform X14

UniProtKB/TrEMBL

D3Z7V3, F8WIH0

Conserved Domains (3) summary

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

TIGR02168
Location:163 → 757

SMC_prok_B; chromosome segregation protein SMC, common bacterial type

cd21911
Location:163 → 225

CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein
XM_036158926.1 → XP_036014819.1 sarcolemmal membrane-associated protein isoform X15

UniProtKB/TrEMBL

F8WIH0

Conserved Domains (3) summary

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

TIGR02168
Location:163 → 757

SMC_prok_B; chromosome segregation protein SMC, common bacterial type

cd21911
Location:163 → 225

CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein
XM_036158927.1 → XP_036014820.1 sarcolemmal membrane-associated protein isoform X16

UniProtKB/TrEMBL

F8WIH0

Conserved Domains (3) summary

COG1196
Location:161 → 754

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd21911
Location:163 → 225

CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein
XM_036158933.1 → XP_036014826.1 sarcolemmal membrane-associated protein isoform X24

UniProtKB/TrEMBL

F8WIH0

Conserved Domains (3) summary

COG1196
Location:161 → 733

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd21911
Location:163 → 225

CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein
XM_036158930.1 → XP_036014823.1 sarcolemmal membrane-associated protein isoform X19

UniProtKB/TrEMBL

F8WIH0

Conserved Domains (3) summary

COG1196
Location:161 → 750

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd21911
Location:163 → 225

CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein
XM_036158931.1 → XP_036014824.1 sarcolemmal membrane-associated protein isoform X20

Conserved Domains (3) summary

COG1196
Location:161 → 750

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd21911
Location:163 → 225

CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein
XM_036158924.1 → XP_036014817.1 sarcolemmal membrane-associated protein isoform X13

Conserved Domains (3) summary

COG1196
Location:161 → 771

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd21911
Location:163 → 225

CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein
XM_006519725.2 → XP_006519788.1 sarcolemmal membrane-associated protein isoform X1

Conserved Domains (2) summary

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

TIGR02168
Location:163 → 812

SMC_prok_B; chromosome segregation protein SMC, common bacterial type
XM_036158932.1 → XP_036014825.1 sarcolemmal membrane-associated protein isoform X22

UniProtKB/TrEMBL

F8WIH0

Conserved Domains (3) summary

COG1196
Location:161 → 737

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd21911
Location:163 → 225

CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein
XM_006519727.3 → XP_006519790.1 sarcolemmal membrane-associated protein isoform X2

UniProtKB/TrEMBL

F8WIH0, H7BX64

Related

ENSMUSP00000087836.5, ENSMUST00000090359.11

Conserved Domains (2) summary

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

TIGR02168
Location:163 → 795

SMC_prok_B; chromosome segregation protein SMC, common bacterial type
XM_030248101.2 → XP_030103961.1 sarcolemmal membrane-associated protein isoform X25

UniProtKB/TrEMBL

F8WIH0

Conserved Domains (2) summary

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

TIGR02168
Location:163 → 732

SMC_prok_B; chromosome segregation protein SMC, common bacterial type
XM_006519737.3 → XP_006519800.1 sarcolemmal membrane-associated protein isoform X27

UniProtKB/TrEMBL

F8WIH0

Conserved Domains (2) summary

COG0419
Location:167 → 717

SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
XM_006519735.3 → XP_006519798.1 sarcolemmal membrane-associated protein isoform X21

UniProtKB/TrEMBL

F8WIH0

Conserved Domains (2) summary

COG1196
Location:161 → 737

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
XM_006519729.3 → XP_006519792.1 sarcolemmal membrane-associated protein isoform X7

UniProtKB/TrEMBL

F8WIH0

Related

ENSMUSP00000107950.3, ENSMUST00000112331.9

Conserved Domains (2) summary

COG1196
Location:161 → 778

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
XM_036158922.1 → XP_036014815.1 sarcolemmal membrane-associated protein isoform X8

UniProtKB/TrEMBL

F8WIH0

Conserved Domains (3) summary

COG1196
Location:161 → 778

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd21911
Location:163 → 225

CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein
XM_017316229.3 → XP_017171718.1 sarcolemmal membrane-associated protein isoform X23

UniProtKB/TrEMBL

F8WIH0

Conserved Domains (2) summary

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

TIGR02168
Location:163 → 733

SMC_prok_B; chromosome segregation protein SMC, common bacterial type
XM_036158934.1 → XP_036014827.1 sarcolemmal membrane-associated protein isoform X26

UniProtKB/TrEMBL

F8WIH0

Conserved Domains (3) summary

COG1196
Location:161 → 733

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd21911
Location:163 → 225

CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein
XM_006519730.3 → XP_006519793.1 sarcolemmal membrane-associated protein isoform X10

UniProtKB/TrEMBL

F8WIH0

Conserved Domains (2) summary

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

TIGR02168
Location:163 → 774

SMC_prok_B; chromosome segregation protein SMC, common bacterial type
XM_036158929.1 → XP_036014822.1 sarcolemmal membrane-associated protein isoform X18

Conserved Domains (3) summary

COG1196
Location:161 → 754

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd21911
Location:163 → 225

CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein
XM_006519726.3 → XP_006519789.1 sarcolemmal membrane-associated protein isoform X3

UniProtKB/TrEMBL

F8WIH0

Conserved Domains (2) summary

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

TIGR02168
Location:163 → 795

SMC_prok_B; chromosome segregation protein SMC, common bacterial type
XM_036158921.1 → XP_036014814.1 sarcolemmal membrane-associated protein isoform X5

UniProtKB/TrEMBL

F8WIH0

Conserved Domains (3) summary

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

TIGR02168
Location:163 → 795

SMC_prok_B; chromosome segregation protein SMC, common bacterial type

cd21911
Location:163 → 225

CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein
XM_006519731.3 → XP_006519794.1 sarcolemmal membrane-associated protein isoform X9

UniProtKB/TrEMBL

F8WIH0

Conserved Domains (2) summary

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

TIGR02168
Location:163 → 774

SMC_prok_B; chromosome segregation protein SMC, common bacterial type
XM_036158923.1 → XP_036014816.1 sarcolemmal membrane-associated protein isoform X11

UniProtKB/TrEMBL

F8WIH0

Conserved Domains (3) summary

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

TIGR02168
Location:156 → 774

SMC_prok_B; chromosome segregation protein SMC, common bacterial type

cd21911
Location:163 → 225

CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein
XM_036158928.1 → XP_036014821.1 sarcolemmal membrane-associated protein isoform X17

Conserved Domains (3) summary

COG1196
Location:161 → 754

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd21911
Location:163 → 225

CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein
XM_036158920.1 → XP_036014813.1 sarcolemmal membrane-associated protein isoform X4

UniProtKB/TrEMBL

F8WIH0

Conserved Domains (3) summary

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

TIGR02168
Location:156 → 795

SMC_prok_B; chromosome segregation protein SMC, common bacterial type

cd21911
Location:163 → 225

CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein
XM_006519728.3 → XP_006519791.1 sarcolemmal membrane-associated protein isoform X6

UniProtKB/TrEMBL

F8WIH0

Conserved Domains (2) summary

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

TIGR02168
Location:163 → 791

SMC_prok_B; chromosome segregation protein SMC, common bacterial type
XM_006519732.3 → XP_006519795.1 sarcolemmal membrane-associated protein isoform X12

UniProtKB/TrEMBL

F8WIH0

Conserved Domains (2) summary

COG1196
Location:161 → 771

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd00060
Location:14 → 108

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
XM_036158936.1 → XP_036014829.1 sarcolemmal membrane-associated protein isoform X30

Conserved Domains (1) summary

COG1196
Location:67 → 335

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
XM_036158937.1 → XP_036014830.1 sarcolemmal membrane-associated protein isoform X31

UniProtKB/TrEMBL

F6UV57

Conserved Domains (1) summary

COG1196
Location:67 → 335

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
XM_006519738.4 → XP_006519801.1 sarcolemmal membrane-associated protein isoform X29

UniProtKB/TrEMBL

F6YCM8

Related

ENSMUSP00000117276.2, ENSMUST00000145738.8

Conserved Domains (1) summary

TIGR02168
Location:66 → 376

SMC_prok_B; chromosome segregation protein SMC, common bacterial type