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    Zfp938 zinc finger protein 938 [ Mus musculus (house mouse) ]

    Gene ID: 237411, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Zfp938provided by MGI
    Official Full Name
    zinc finger protein 938provided by MGI
    Primary source
    MGI:MGI:3621440
    See related
    Ensembl:ENSMUSG00000062931 AllianceGenome:MGI:3621440
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    B230315N10Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF101 (zinc finger protein 101) and ZNF699 (zinc finger protein 699). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E18 (RPKM 5.6), frontal lobe adult (RPKM 4.8) and 16 other tissues See more
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    Genomic context

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    Location:
    10 C1; 10 39.72 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (82060684..82077114, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (82224850..82241280, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40720 Neighboring gene mitochondrial pyruvate carrier 2 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E8352 Neighboring gene STARR-seq mESC enhancer starr_27359 Neighboring gene SPATA31 subfamily H member 1 Neighboring gene STARR-positive B cell enhancer mm9_chr10:81816788-81817089 Neighboring gene predicted gene 4924

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
    2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Clone Names

    • MGC19022

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC237411

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105557.2 → NP_001099027.2  uncharacterized protein LOC237411 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC160865
      Consensus CDS
      CCDS48652.1
      UniProtKB/TrEMBL
      E9Q9G3
      Related
      ENSMUSP00000047110.9, ENSMUST00000041264.15
      Conserved Domains (5) summary
      smart00349
      Location:4 → 45
      KRAB; krueppel associated box
      COG5048
      Location:159 → 534
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:437 → 457
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:4 → 41
      KRAB; KRAB box
      pfam13465
      Location:449 → 474
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001379437.1 → NP_001366366.1  uncharacterized protein LOC237411 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC160865
      Conserved Domains (2) summary
      COG5048
      Location:229 → 512
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:399 → 419
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. NM_001379438.1 → NP_001366367.1  uncharacterized protein LOC237411 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC160865
      Conserved Domains (3) summary
      COG5048
      Location:261 → 544
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:431 → 451
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:2 → 38
      KRAB; KRAB box

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      82060684..82077114 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_172789.1: Suppressed sequence

      Description
      NM_172789.1: This RefSeq was permanently suppressed because it does not originate from this locus and appears to be spurious transcription that is not sufficient evidence to define a distinct locus.
    Nucleotide Protein Strain
    Heading Accession and Version

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