Fbxw9 F-box and WD-40 domain protein 9 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Fbxw9provided by MGI
Official Full Name: F-box and WD-40 domain protein 9provided by MGI
Primary source: MGI:MGI:1915878
See related: Ensembl:ENSMUSG00000008167 AllianceGenome:MGI:1915878
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Fbw9; 1110017H11Rik
Summary: Predicted to be part of preribosome, large subunit precursor. Is expressed in brain; endocrine gland; genitourinary system; spinal cord; and trigeminal nerve. Orthologous to human FBXW9 (F-box and WD repeat domain containing 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in testis adult (RPKM 27.8), ovary adult (RPKM 26.8) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 8 C3; 8 41.54 cM

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	8	NC_000074.7 (85786748..85793750)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	8	NC_000074.6 (85060119..85067121)

Chromosome 8 - NC_000074.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (2)

General gene information

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General protein information

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Preferred Names: F-box/WD repeat-containing protein 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_026791.2 → NP_081067.2 F-box/WD repeat-containing protein 9

See identical proteins and their annotated locations for NP_081067.2

Status: VALIDATED

Source sequence(s)

BB870341, BC060082, BP769909, CF197934

Consensus CDS

CCDS40418.1

UniProtKB/TrEMBL

F8VPX2, Q80XN6

Related

ENSMUSP00000092845.4, ENSMUST00000095220.4

Conserved Domains (3) summary

COG2319
Location:167 → 456

WD40; WD40 repeat [General function prediction only]

sd00039
Location:177 → 224

7WD40; WD40 repeat [structural motif]

cl02567
Location:171 → 413

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...