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    ppargc1b peroxisome proliferator-activated receptor gamma, coactivator 1 beta [ Danio rerio (zebrafish) ]

    Gene ID: 555906, updated on 27-Mar-2024

    Summary

    Official Symbol
    ppargc1bprovided by ZNC
    Official Full Name
    peroxisome proliferator-activated receptor gamma, coactivator 1 betaprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030616-43
    See related
    Ensembl:ENSDARG00000101569 AllianceGenome:ZFIN:ZDB-GENE-030616-43
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    PERC; perc1b; fb55c08; sb:cb520; wu:fb55c08; si:bz1d10.4
    Summary
    Predicted to enable nuclear receptor coactivator activity. Predicted to be involved in positive regulation of DNA-binding transcription factor activity and positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including cardiovascular system; cranial ganglion; immature eye; male organism; and retina. Human ortholog(s) of this gene implicated in obesity. Orthologous to human PPARGC1B (PPARG coactivator 1 beta). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    Location:
    chromosome: 14
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (24935054..25001584)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (24637858..24703338)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110440208 Neighboring gene Rho guanine nucleotide exchange factor (GEF) 37 Neighboring gene phosphodiesterase 6A, cGMP-specific, rod, alpha Neighboring gene transmembrane protein 216

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nuclear receptor coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transcription factor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    peroxisome proliferator-activated receptor gamma coactivator 1-beta
    Names
    peroxisome proliferative activated receptor, gamma, coactivator 1, beta

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      24935054..25001584
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009291061.3XP_009289336.1  peroxisome proliferator-activated receptor gamma coactivator 1-beta

      UniProtKB/TrEMBL
      A0A8M3AP47
      Related
      ENSDARP00000132754.1, ENSDART00000170871.2
      Conserved Domains (1) summary
      cl17169
      Location:737823
      RRM_SF; RNA recognition motif (RRM) superfamily