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    CG11037 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40317, updated on 10-May-2024

    Summary

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    Official Symbol
    CG11037provided by FlyBase
    Primary source
    FLYBASE:FBgn0037038
    Locus tag
    Dmel_CG11037
    See related
    AllianceGenome:FB:FBgn0037038
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG11037; SP191
    Summary
    Enables serine hydrolase activity. Involved in multicellular organism reproduction. Located in extracellular space. Is expressed in adult head. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG11037 in Genome Data Viewer
    Location:
    78A1-78A1; 3-47 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (20960398..20961386, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (20953498..20954486, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45243 Neighboring gene Seminase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular evolution of the sex peptide network in Drosophila. McGeary MK, et al. J Evol Biol, 2020 May. PMID 31991034
    2. Evolutionary rate covariation identifies new members of a protein network required for Drosophila melanogaster female post-mating responses. Findlay GD, et al. PLoS Genet, 2014 Jan. PMID 24453993, Free PMC Article
    3. Identification and function of proteolysis regulators in seminal fluid. Laflamme BA, et al. Mol Reprod Dev, 2013 Feb. PMID 23109270, Free PMC Article
    4. Temporally variable selection on proteolysis-related reproductive tract proteins in Drosophila. Wong A, et al. Mol Biol Evol, 2012 Jan. PMID 21940639, Free PMC Article
    5. Seminal influences: Drosophila Acps and the molecular interplay between males and females during reproduction. Ravi Ram K, et al. Integr Comp Biol, 2007 Sep. PMID 21672851

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine hydrolase activity HDA PubMed 
    enables serine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    involved_in sexual reproduction HEP PubMed 
    Component Evidence Code Pubs
    located_in extracellular space HDA PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11037-PA
    NP_649272.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      20960398..20961386 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141015.2 → NP_649272.1  uncharacterized protein Dmel_CG11037 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649272.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C0MIV0, Q8T429, Q9VP93
      Related
      FBpp0077990
      Conserved Domains (2) summary
      smart00020
      Location:61 → 281
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:62 → 283
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T429 Q8T429

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