Ppp1r16a protein phosphatase 1, regulatory subunit 16A [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ppp1r16aprovided by RGD
Official Full Name: protein phosphatase 1, regulatory subunit 16Aprovided by RGD
Primary source: RGD:1307962
See related: Ensembl:ENSRNOG00000015450 AllianceGenome:RGD:1307962
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable myosin phosphatase regulator activity and protein phosphatase 1 binding activity. Predicted to be involved in regulation of protein dephosphorylation. Predicted to be active in plasma membrane. Orthologous to human PPP1R16A (protein phosphatase 1 regulatory subunit 16A). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Lung (RPKM 91.0), Kidney (RPKM 63.1) and 9 other tissues See more
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 7q34

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (110272307..110295452)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (108391664..108414812)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (117734002..117757249)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables enzyme inhibitor activity	IBA Inferred from Biological aspect of Ancestor more info
enables myosin phosphatase regulator activity	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: protein phosphatase 1 regulatory subunit 16A

Names: protein phosphatase 1, regulatory (inhibitor) subunit 16A

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001130566.1 → NP_001124038.1 protein phosphatase 1 regulatory subunit 16A

See identical proteins and their annotated locations for NP_001124038.1

Status: PROVISIONAL

Source sequence(s)

CH473950

UniProtKB/TrEMBL

A0A8I6A2T7, A6HSC4

Related

ENSRNOP00000020768.2, ENSRNOT00000020768.4

Conserved Domains (4) summary

cd00204
Location:99 → 286

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam12796
Location:76 → 168

Ank_2; Ankyrin repeats (3 copies)

pfam13637
Location:205 → 253

Ank_4; Ankyrin repeats (many copies)

sd00045
Location:75 → 102

ANK; ANK repeat [structural motif]