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    RIOK2 RIO kinase 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 479147, updated on 5-Mar-2024

    Summary

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    Official Symbol
    RIOK2provided by VGNC
    Official Full Name
    RIO kinase 2provided by VGNC
    Primary source
    VGNC:VGNC:53201
    See related
    Ensembl:ENSCAFG00845002323
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See RIOK2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 3 NC_051807.1 (12432261..12454732)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 3 NC_006585.4 (13888964..13911359)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 3 NC_049224.1 (12587610..12610085)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 3 NC_049263.1 (12386660..12409131)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 3 NC_049744.1 (12387940..12410400)

    Chromosome 3 - NC_051807.1Genomic Context describing neighboring genes Neighboring gene U4 spliceosomal RNA Neighboring gene uncharacterized LOC119870736 Neighboring gene limb and CNS expressed 1 Neighboring gene 2'-5'-oligoadenylate synthase 3-like Neighboring gene leucyl and cystinyl aminopeptidase Neighboring gene small nucleolar RNA SNORA13

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in maturation of SSU-rRNA IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of preribosome, small subunit precursor IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase RIO2
    XP_005618121.1
    XP_022272399.1
    XP_022272400.1
    XP_022272401.1
    XP_038327235.1
    XP_038327236.1
    XP_038327237.1
    XP_038327238.1
    XP_038327239.1
    XP_038388179.1
    XP_038388180.1
    XP_038388181.1
    XP_038388182.1
    XP_038388183.1
    XP_038452429.1
    XP_038452430.1
    XP_038452431.1
    XP_038452432.1
    XP_038452434.1
    XP_038516668.1
    XP_038516669.1
    XP_038516670.1
    XP_038516671.1
    XP_038516672.1
    XP_536291.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051807.1 Reference ROS_Cfam_1.0

      Range
      12432261..12454732
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038660740.1 → XP_038516668.1  serine/threonine-protein kinase RIO2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KEF3
      Conserved Domains (3) summary
      PRK08581
      Location:336 → 496
      PRK08581; amidase domain-containing protein
      cd05144
      Location:102 → 284
      RIO2_C; C-terminal catalytic domain of the atypical protein serine kinase, RIO2 kinase
      pfam09202
      Location:9 → 99
      Rio2_N; Rio2, N-terminal

    2. XM_038660741.1 → XP_038516669.1  serine/threonine-protein kinase RIO2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0KEF3, A0A8C0SRR6, A0A8I3RQM4
      Related
      ENSCAFP00845003283.1, ENSCAFT00845004099.1
      Conserved Domains (2) summary
      cd05144
      Location:94 → 276
      RIO2_C; C-terminal catalytic domain of the atypical protein serine kinase, RIO2 kinase
      pfam09202
      Location:9 → 91
      Rio2_N; Rio2, N-terminal

    3. XM_038660744.1 → XP_038516672.1  serine/threonine-protein kinase RIO2 isoform X5

      UniProtKB/TrEMBL
      A0A8C0NIF2
      Conserved Domains (2) summary
      cd05144
      Location:77 → 259
      RIO2_C; C-terminal catalytic domain of the atypical protein serine kinase, RIO2 kinase
      pfam09202
      Location:6 → 74
      Rio2_N; Rio2, N-terminal

    4. XM_038660743.1 → XP_038516671.1  serine/threonine-protein kinase RIO2 isoform X4

      UniProtKB/TrEMBL
      A0A8C0NIF2
      Conserved Domains (2) summary
      cd05144
      Location:85 → 267
      RIO2_C; C-terminal catalytic domain of the atypical protein serine kinase, RIO2 kinase
      pfam09202
      Location:6 → 82
      Rio2_N; Rio2, N-terminal

    5. XM_038660742.1 → XP_038516670.1  serine/threonine-protein kinase RIO2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0NIF2
      Conserved Domains (3) summary
      PRK08581
      Location:324 → 484
      PRK08581; amidase domain-containing protein
      cd05144
      Location:90 → 272
      RIO2_C; C-terminal catalytic domain of the atypical protein serine kinase, RIO2 kinase
      pfam09202
      Location:11 → 87
      Rio2_N; Rio2, N-terminal

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049263.1 Alternate UMICH_Zoey_3.1

      Range
      12386660..12409131
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038471307.1 → XP_038327235.1  serine/threonine-protein kinase RIO2 isoform X1

      Conserved Domains (3) summary
      PRK08581
      Location:336 → 496
      PRK08581; amidase domain-containing protein
      cd05144
      Location:102 → 284
      RIO2_C; C-terminal catalytic domain of the atypical protein serine kinase, RIO2 kinase
      pfam09202
      Location:9 → 99
      Rio2_N; Rio2, N-terminal

    2. XM_038471308.1 → XP_038327236.1  serine/threonine-protein kinase RIO2 isoform X2

      Conserved Domains (2) summary
      cd05144
      Location:94 → 276
      RIO2_C; C-terminal catalytic domain of the atypical protein serine kinase, RIO2 kinase
      pfam09202
      Location:9 → 91
      Rio2_N; Rio2, N-terminal

    3. XM_038471311.1 → XP_038327239.1  serine/threonine-protein kinase RIO2 isoform X5

      Conserved Domains (2) summary
      cd05144
      Location:77 → 259
      RIO2_C; C-terminal catalytic domain of the atypical protein serine kinase, RIO2 kinase
      pfam09202
      Location:6 → 74
      Rio2_N; Rio2, N-terminal

    4. XM_038471310.1 → XP_038327238.1  serine/threonine-protein kinase RIO2 isoform X4

      Conserved Domains (2) summary
      cd05144
      Location:85 → 267
      RIO2_C; C-terminal catalytic domain of the atypical protein serine kinase, RIO2 kinase
      pfam09202
      Location:6 → 82
      Rio2_N; Rio2, N-terminal

    5. XM_038471309.1 → XP_038327237.1  serine/threonine-protein kinase RIO2 isoform X3

      Conserved Domains (3) summary
      PRK08581
      Location:324 → 484
      PRK08581; amidase domain-containing protein
      cd05144
      Location:90 → 272
      RIO2_C; C-terminal catalytic domain of the atypical protein serine kinase, RIO2 kinase
      pfam09202
      Location:11 → 87
      Rio2_N; Rio2, N-terminal

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049744.1 Alternate UNSW_CanFamBas_1.0

      Range
      12387940..12410400
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038596502.1 → XP_038452430.1  serine/threonine-protein kinase RIO2 isoform X2

    2. XM_038596501.1 → XP_038452429.1  serine/threonine-protein kinase RIO2 isoform X1

    3. XM_038596506.1 → XP_038452434.1  serine/threonine-protein kinase RIO2 isoform X5

    4. XM_038596504.1 → XP_038452432.1  serine/threonine-protein kinase RIO2 isoform X4

    5. XM_038596503.1 → XP_038452431.1  serine/threonine-protein kinase RIO2 isoform X3

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049224.1 Alternate UU_Cfam_GSD_1.0

      Range
      12587610..12610085
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038532251.1 → XP_038388179.1  serine/threonine-protein kinase RIO2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KEF3
      Conserved Domains (3) summary
      PRK08581
      Location:336 → 496
      PRK08581; amidase domain-containing protein
      cd05144
      Location:102 → 284
      RIO2_C; C-terminal catalytic domain of the atypical protein serine kinase, RIO2 kinase
      pfam09202
      Location:9 → 99
      Rio2_N; Rio2, N-terminal

    2. XM_038532252.1 → XP_038388180.1  serine/threonine-protein kinase RIO2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0KEF3, A0A8C0SRR6, A0A8I3RQM4
      Conserved Domains (2) summary
      cd05144
      Location:94 → 276
      RIO2_C; C-terminal catalytic domain of the atypical protein serine kinase, RIO2 kinase
      pfam09202
      Location:9 → 91
      Rio2_N; Rio2, N-terminal

    3. XM_038532255.1 → XP_038388183.1  serine/threonine-protein kinase RIO2 isoform X5

      UniProtKB/TrEMBL
      A0A8C0NIF2
      Conserved Domains (2) summary
      cd05144
      Location:77 → 259
      RIO2_C; C-terminal catalytic domain of the atypical protein serine kinase, RIO2 kinase
      pfam09202
      Location:6 → 74
      Rio2_N; Rio2, N-terminal

    4. XM_038532254.1 → XP_038388182.1  serine/threonine-protein kinase RIO2 isoform X4

      UniProtKB/TrEMBL
      A0A8C0NIF2
      Conserved Domains (2) summary
      cd05144
      Location:85 → 267
      RIO2_C; C-terminal catalytic domain of the atypical protein serine kinase, RIO2 kinase
      pfam09202
      Location:6 → 82
      Rio2_N; Rio2, N-terminal

    5. XM_038532253.1 → XP_038388181.1  serine/threonine-protein kinase RIO2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0NIF2
      Conserved Domains (3) summary
      PRK08581
      Location:324 → 484
      PRK08581; amidase domain-containing protein
      cd05144
      Location:90 → 272
      RIO2_C; C-terminal catalytic domain of the atypical protein serine kinase, RIO2 kinase
      pfam09202
      Location:11 → 87
      Rio2_N; Rio2, N-terminal

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006585.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      13888964..13911359
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022416691.2 → XP_022272399.1  serine/threonine-protein kinase RIO2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KEF3
      Conserved Domains (3) summary
      PRK08581
      Location:336 → 496
      PRK08581; amidase domain-containing protein
      cd05144
      Location:102 → 284
      RIO2_C; C-terminal catalytic domain of the atypical protein serine kinase, RIO2 kinase
      pfam09202
      Location:9 → 99
      Rio2_N; Rio2, N-terminal

    2. XM_536291.6 → XP_536291.3  serine/threonine-protein kinase RIO2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0KEF3, A0A8C0SRR6, A0A8I3RQM4
      Conserved Domains (2) summary
      cd05144
      Location:94 → 276
      RIO2_C; C-terminal catalytic domain of the atypical protein serine kinase, RIO2 kinase
      pfam09202
      Location:9 → 91
      Rio2_N; Rio2, N-terminal

    3. XM_005618064.3 → XP_005618121.1  serine/threonine-protein kinase RIO2 isoform X5

      UniProtKB/TrEMBL
      A0A8C0NIF2
      Conserved Domains (2) summary
      cd05144
      Location:77 → 259
      RIO2_C; C-terminal catalytic domain of the atypical protein serine kinase, RIO2 kinase
      pfam09202
      Location:6 → 74
      Rio2_N; Rio2, N-terminal

    4. XM_022416693.2 → XP_022272401.1  serine/threonine-protein kinase RIO2 isoform X4

      UniProtKB/TrEMBL
      A0A8C0NIF2
      Conserved Domains (2) summary
      cd05144
      Location:85 → 267
      RIO2_C; C-terminal catalytic domain of the atypical protein serine kinase, RIO2 kinase
      pfam09202
      Location:6 → 82
      Rio2_N; Rio2, N-terminal

    5. XM_022416692.2 → XP_022272400.1  serine/threonine-protein kinase RIO2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0NIF2
      Conserved Domains (3) summary
      PRK08581
      Location:324 → 484
      PRK08581; amidase domain-containing protein
      cd05144
      Location:90 → 272
      RIO2_C; C-terminal catalytic domain of the atypical protein serine kinase, RIO2 kinase
      pfam09202
      Location:11 → 87
      Rio2_N; Rio2, N-terminal
    Nucleotide Protein
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