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    tpd52l2b tpd52 like 2b [ Danio rerio (zebrafish) ]

    Gene ID: 322103, updated on 27-Mar-2024

    Summary

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    Official Symbol
    tpd52l2bprovided by ZNC
    Official Full Name
    tpd52 like 2bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-822
    See related
    Ensembl:ENSDARG00000013655 AllianceGenome:ZFIN:ZDB-GENE-030131-822
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    tpd52l2; zgc:55294; zgc:77690; wu:fb50b02
    Summary
    Predicted to be active in cytoplasm. Orthologous to human TPD52L2 (TPD52 like 2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See tpd52l2b in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (17431344..17450829, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (17505001..17524491, complement)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene transfer RNA glutamic acid (anticodon CUC) Neighboring gene pancreatic progenitor cell differentiation and proliferation factor b Neighboring gene tripartite motif containing 101 Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 5ab

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. High-Resolution Proteomic Profiling Shows Sexual Dimorphism in Zebrafish Heart-Associated Proteins. Niksirat H, et al. J Proteome Res, 2021 Aug 6. PMID 34185526
    2. RNA-Seq analysis in mutant zebrafish reveals role of U1C protein in alternative splicing regulation. Rösel TD, et al. EMBO J, 2011 May 18. PMID 21468032, Free PMC Article
    3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    4. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    5. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC77690

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    tpd52 like 2b; tumor protein D54
    Names
    tumor protein D52-like 2
    tumor protein D52-like 2b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199582.2 → NP_955876.2  tpd52 like 2b isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      BC063969, EH444392, EH481571
      UniProtKB/TrEMBL
      A0A8M1PFI4, F1QXG8
      Related
      ENSDARP00000023199.6, ENSDART00000005366.8
      Conserved Domains (1) summary
      pfam04201
      Location:56 → 189
      TPD52; Tumour protein D52 family

    2. NM_200885.2 → NP_957179.1  tpd52 like 2b isoform 2

      See identical proteins and their annotated locations for NP_957179.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      BC063969, EH444392, EH481571
      UniProtKB/TrEMBL
      A0A8M1PDM4, Q6P3J1
      Related
      ENSDARP00000095451.3, ENSDART00000104680.5
      Conserved Domains (1) summary
      pfam04201
      Location:56 → 173
      TPD52; Tumour protein D52 family

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      17431344..17450829 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005162037.2 → XP_005162094.1  tumor protein D54 isoform X9

      UniProtKB/TrEMBL
      A0A8M2B8X1
      Related
      ENSDARP00000121790.1, ENSDART00000133125.2
      Conserved Domains (1) summary
      pfam04201
      Location:56 → 187
      TPD52; Tumour protein D52 family

    2. XM_005162035.2 → XP_005162092.1  tumor protein D54 isoform X7

      UniProtKB/TrEMBL
      A0A8M2B8U5, E9QCR8
      Related
      ENSDARP00000117802.1, ENSDART00000145719.3
      Conserved Domains (1) summary
      pfam04201
      Location:56 → 197
      TPD52; Tumour protein D52 family

    3. XM_005162032.2 → XP_005162089.1  tumor protein D54 isoform X4

      UniProtKB/TrEMBL
      A0A8M2B964
      Conserved Domains (1) summary
      pfam04201
      Location:56 → 213
      TPD52; Tumour protein D52 family

    4. XM_021469744.1 → XP_021325419.1  tumor protein D54 isoform X6

      UniProtKB/TrEMBL
      A0A8M9PKL1, E9QG45
      Related
      ENSDARP00000115511.1, ENSDART00000145399.3
      Conserved Domains (1) summary
      pfam04201
      Location:56 → 209
      TPD52; tumor protein D52 family

    5. XM_021469742.1 → XP_021325417.1  tumor protein D54 isoform X3

      UniProtKB/TrEMBL
      A0A8M9P507
      Conserved Domains (1) summary
      pfam04201
      Location:56 → 223
      TPD52; tumor protein D52 family

    6. XM_021469740.1 → XP_021325415.1  tumor protein D54 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PWB5
      Conserved Domains (1) summary
      pfam04201
      Location:56 → 233
      TPD52; tumor protein D52 family

    7. XM_005162036.3 → XP_005162093.1  tumor protein D54 isoform X8

      UniProtKB/TrEMBL
      A0A8M2B8Z1, E9QEC8
      Related
      ENSDARP00000117901.1, ENSDART00000147524.3
      Conserved Domains (1) summary
      pfam04201
      Location:56 → 196
      TPD52; Tumour protein D52 family

    8. XM_005162033.3 → XP_005162090.1  tumor protein D54 isoform X5

      UniProtKB/TrEMBL
      A0A2R8Q9R2, A0A8M2B8U6
      Related
      ENSDARP00000148142.1, ENSDART00000190748.1
      Conserved Domains (1) summary
      pfam04201
      Location:56 → 212
      TPD52; Tumour protein D52 family

    9. XM_021469741.1 → XP_021325416.1  tumor protein D54 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PSW8
      Conserved Domains (1) summary
      pfam04201
      Location:56 → 232
      TPD52; tumor protein D52 family

    10. XM_021469745.1 → XP_021325420.1  tumor protein D54 isoform X10

      UniProtKB/TrEMBL
      A0A8M9PWC0
      Conserved Domains (1) summary
      pfam04201
      Location:56 → 149
      TPD52; tumor protein D52 family
    Nucleotide Protein Strain
    Heading Accession and Version

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