sdr16c5b short chain dehydrogenase/reductase family 16C, member 5b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: sdr16c5bprovided by ZNC
Official Full Name: short chain dehydrogenase/reductase family 16C, member 5bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2861
See related: Ensembl:ENSDARG00000017794 AllianceGenome:ZFIN:ZDB-GENE-040426-2861
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: rdhe2; sdr16c5; zgc:63829; wu:fj05d06
Summary: Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be active in lipid droplet. Is expressed in liver. Orthologous to human SDR16C5 (short chain dehydrogenase/reductase family 16C member 5). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human all
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Genomic context

Location:: chromosome: 7

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (58699745..58718472)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (58397305..58416032)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb63e10 (e-PCR)
- UniSTS:189041

fj05d06.x1 (e-PCR)
- UniSTS:198392

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables all-trans-retinol dehydrogenase (NAD+) activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in lipid droplet	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: epidermal retinol dehydrogenase 2

Names: epidermal retinal dehydrogenase 2; short chain dehydrogenase/reductase family 16C, member 5

NP_999936.1

EC 1.1.1.105

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_214771.2 → NP_999936.1 epidermal retinol dehydrogenase 2

See identical proteins and their annotated locations for NP_999936.1

Status: PROVISIONAL

Source sequence(s)

BC054138

UniProtKB/TrEMBL

A0A8M1PFP2, Q7SZ49

Related

ENSDARP00000049263.5, ENSDART00000049264.7

Conserved Domains (2) summary

cd05339
Location:38 → 281

17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

pfam00106
Location:39 → 233

adh_short; short chain dehydrogenase