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    ube2l3b ubiquitin-conjugating enzyme E2L 3b [ Danio rerio (zebrafish) ]

    Gene ID: 321943, updated on 25-Apr-2024

    Summary

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    Official Symbol
    ube2l3bprovided by ZNC
    Official Full Name
    ubiquitin-conjugating enzyme E2L 3bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-662
    See related
    Ensembl:ENSDARG00000027141 AllianceGenome:ZFIN:ZDB-GENE-030131-662
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    UBE2L3; ube2l3l; wu:fb38h03
    Summary
    Predicted to enable ubiquitin conjugating enzyme activity and ubiquitin protein ligase binding activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be part of ubiquitin ligase complex. Predicted to be active in nucleus. Orthologous to human UBE2L3 (ubiquitin conjugating enzyme E2 L3). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See ube2l3b in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (13337507..13353898, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (12837291..12853681, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene stromal cell-derived factor 2-like 1 Neighboring gene YdjC chitooligosaccharide deacetylase homolog Neighboring gene chemokine (C-C motif) ligand 19a, tandem duplicate 1 Neighboring gene chemokine (C-C motif) ligand 19a, tandem duplicate 2 Neighboring gene tectonic family member 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin conjugating enzyme activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin conjugating enzyme activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin protein ligase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein polyubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitin-conjugating enzyme E2 L3; ubiquitin-conjugating enzyme E2 L3b
    Names
    ubiquitin-conjugating enzyme E2L 3, like
    NP_001076266.1
    XP_005165096.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082797.1 → NP_001076266.1  ubiquitin-conjugating enzyme E2 L3b

      Status: PROVISIONAL

      Source sequence(s)
      BX957246
      UniProtKB/TrEMBL
      A0A8M1NBY9, A2BIR4
      Related
      ENSDARP00000116310.1, ENSDART00000146136.2
      Conserved Domains (2) summary
      smart00212
      Location:46 → 185
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic domain homologues
      COG5078
      Location:44 → 186
      COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      13337507..13353898 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005165039.4 → XP_005165096.1  ubiquitin-conjugating enzyme E2 L3 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BC72, A2BIR3
      Related
      ENSDARP00000008064.5, ENSDART00000004539.7
      Conserved Domains (1) summary
      smart00212
      Location:6 → 149
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic domain homologues
    Nucleotide Protein Strain
    Heading Accession and Version

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