asb16 ankyrin repeat and SOCS box containing 16 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: asb16provided by ZNC
Official Full Name: ankyrin repeat and SOCS box containing 16provided by ZNC
Primary source: ZFIN:ZDB-GENE-031031-3
See related: Ensembl:ENSDARG00000056468 AllianceGenome:ZFIN:ZDB-GENE-031031-3
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:136751
Summary: Predicted to be involved in protein ubiquitination. Predicted to act upstream of or within intracellular signal transduction. Orthologous to human ASB16 (ankyrin repeat and SOCS box containing 16). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (19999400..20011807)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (19849952..19862067)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables transmembrane transporter binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within intracellular signal transduction	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of delayed rectifier potassium channel activity	IBA Inferred from Biological aspect of Ancestor more info
involved_in neuronal action potential	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein ubiquitination	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in axon initial segment	IBA Inferred from Biological aspect of Ancestor more info
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in synapse	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ankyrin repeat and SOCS box protein 16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001040368.1 → NP_001035458.1 ankyrin repeat and SOCS box protein 16

See identical proteins and their annotated locations for NP_001035458.1

Status: PROVISIONAL

Source sequence(s)

BC115251

UniProtKB/TrEMBL

A0A8M1N8V0, Q1RLW6

Related

ENSDARP00000120787.1, ENSDART00000137944.2

Conserved Domains (4) summary

cd00204
Location:88 → 203

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

cd03723
Location:381 → 428

SOCS_ASB4_ASB18; SOCS (suppressors of cytokine signaling) box of ASB4 and ASB18 proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. Asb4 was identified as imprinted gene in mice. The general function of the SOCS box is the ...

pfam12796
Location:90 → 179

Ank_2; Ankyrin repeats (3 copies)

sd00045
Location:88 → 115

ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007114.7 Reference GRCz11 Primary Assembly

Range

19999400..20011807

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021471399.1 → XP_021327074.1 ankyrin repeat and SOCS box protein 16 isoform X1

UniProtKB/TrEMBL

A0A8M9PQB4

Conserved Domains (2) summary

cd00204
Location:125 → 240

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

sd00045
Location:125 → 152

ANK; ANK repeat [structural motif]