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    RGS3 regulator of G protein signaling 3 [ Bos taurus (cattle) ]

    Gene ID: 527349, updated on 5-Mar-2024

    Summary

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    Official Symbol
    RGS3provided by VGNC
    Official Full Name
    regulator of G protein signaling 3provided by VGNC
    Primary source
    VGNC:VGNC:33922
    See related
    BGD:BT29368; Ensembl:ENSBTAG00000004499 Ensembl:ENSBTAG00000063010
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 8
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 8 NC_037335.1 (102677355..102832522)

    Chromosome 8 - NC_037335.1Genomic Context describing neighboring genes Neighboring gene chromosome 8 C9orf43 homolog Neighboring gene DNA polymerase epsilon 3, accessory subunit Neighboring gene small nucleolar RNA SNORA72 Neighboring gene small ribosomal subunit protein eS12-like Neighboring gene uncharacterized LOC101907033

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037335.1 Chromosome 8 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    regulator of G-protein signaling 3
    Names
    regulator of G-protein signalling 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077973.2 → NP_001071441.1  regulator of G-protein signaling 3

      See identical proteins and their annotated locations for NP_001071441.1

      Status: PROVISIONAL

      Source sequence(s)
      BC123615
      UniProtKB/TrEMBL
      F1N7R3, Q05AT4
      Conserved Domains (5) summary
      COG0265
      Location:38 → 93
      DegQ; Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]
      cd00992
      Location:17 → 91
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15756
      Location:520 → 594
      DUF4690; Domain of unknown function (DUF4690)
      pfam16228
      Location:362 → 511
      DUF4887; Domain of unknown function (DUF4887)
      cl02565
      Location:787 → 849
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037335.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      102677355..102832522
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059889111.1 → XP_059745094.1  regulator of G-protein signaling 3 isoform X1

    2. XM_059889115.1 → XP_059745098.1  regulator of G-protein signaling 3 isoform X5

    3. XM_059889113.1 → XP_059745096.1  regulator of G-protein signaling 3 isoform X3

    4. XM_005210526.5 → XP_005210583.2  regulator of G-protein signaling 3 isoform X7

      Related
      ENSBTAP00000080103.1, ENSBTAT00000092407.1
      Conserved Domains (2) summary
      cd08685
      Location:27 → 146
      C2_RGS-like; C2 domain of the Regulator Of G-Protein Signaling (RGS) family
      cd00992
      Location:188 → 260
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

    5. XM_059889112.1 → XP_059745095.1  regulator of G-protein signaling 3 isoform X2

    6. XM_059889114.1 → XP_059745097.1  regulator of G-protein signaling 3 isoform X4

    7. XM_005210524.5 → XP_005210581.1  regulator of G-protein signaling 3 isoform X6

      UniProtKB/TrEMBL
      F1N7R3
      Conserved Domains (5) summary
      cd08713
      Location:787 → 900
      RGS_RGS3; Regulator of G protein signaling (RGS) domain found in the RGS3 protein
      COG0265
      Location:38 → 93
      DegQ; Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]
      cd00992
      Location:17 → 91
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15756
      Location:520 → 594
      DUF4690; Domain of unknown function (DUF4690)
      pfam16228
      Location:362 → 511
      DUF4887; Domain of unknown function (DUF4887)

    8. XM_024995751.2 → XP_024851519.1  regulator of G-protein signaling 3 isoform X10

      Conserved Domains (1) summary
      cd00992
      Location:17 → 91
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

    9. XM_024995750.2 → XP_024851518.1  regulator of G-protein signaling 3 isoform X9

      Conserved Domains (2) summary
      cd08713
      Location:389 → 502
      RGS_RGS3; Regulator of G protein signaling (RGS) domain found in the RGS3 protein
      cl26464
      Location:22 → 173
      Atrophin-1; Atrophin-1 family

    10. XM_059889117.1 → XP_059745100.1  regulator of G-protein signaling 3 isoform X9

    11. XM_005210529.5 → XP_005210586.1  regulator of G-protein signaling 3 isoform X9

      See identical proteins and their annotated locations for XP_005210586.1

      Conserved Domains (2) summary
      cd08713
      Location:389 → 502
      RGS_RGS3; Regulator of G protein signaling (RGS) domain found in the RGS3 protein
      cl26464
      Location:22 → 173
      Atrophin-1; Atrophin-1 family

    12. XM_024995748.2 → XP_024851516.1  regulator of G-protein signaling 3 isoform X8

      Conserved Domains (2) summary
      cd08713
      Location:417 → 530
      RGS_RGS3; Regulator of G protein signaling (RGS) domain found in the RGS3 protein
      cl28033
      Location:27 → 260
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

    13. XM_059889118.1 → XP_059745101.1  regulator of G-protein signaling 3 isoform X9

    14. XM_010808261.4 → XP_010806563.1  regulator of G-protein signaling 3 isoform X12

      See identical proteins and their annotated locations for XP_010806563.1

      Conserved Domains (1) summary
      cd08713
      Location:44 → 157
      RGS_RGS3; Regulator of G protein signaling (RGS) domain found in the RGS3 protein

    15. XM_015472689.3 → XP_015328175.1  regulator of G-protein signaling 3 isoform X11

      UniProtKB/TrEMBL
      F1MM15
      Related
      ENSBTAP00000053205.3, ENSBTAT00000061169.4
      Conserved Domains (1) summary
      cd08713
      Location:68 → 181
      RGS_RGS3; Regulator of G protein signaling (RGS) domain found in the RGS3 protein

    16. XM_024995752.2 → XP_024851520.1  regulator of G-protein signaling 3 isoform X12

      Conserved Domains (1) summary
      cd08713
      Location:44 → 157
      RGS_RGS3; Regulator of G protein signaling (RGS) domain found in the RGS3 protein
    Nucleotide Protein Strain
    Heading Accession and Version

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