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    uri1 URI1 prefoldin like chaperone [ Danio rerio (zebrafish) ]

    Gene ID: 560572, updated on 27-Mar-2024

    Summary

    Official Symbol
    uri1provided by ZNC
    Official Full Name
    URI1 prefoldin like chaperoneprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050913-30
    See related
    Ensembl:ENSDARG00000026664 AllianceGenome:ZFIN:ZDB-GENE-050913-30
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fb52f03; zgc:110109
    Summary
    Predicted to enable chromatin binding activity; phosphatase inhibitor activity; and transcription corepressor activity. Predicted to be involved in negative regulation of phosphatase activity and negative regulation of transcription by RNA polymerase II. Orthologous to human URI1 (URI1 prefoldin like chaperone). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See uri1 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (14693723..14705821)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (14725211..14737309)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated 2-like Neighboring gene peptide deformylase, mitochondrial Neighboring gene teashirt zinc finger homeobox 3a Neighboring gene MTSS I-BAR domain containing 2a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC110109

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phosphatase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transcription corepressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    unconventional prefoldin RPB5 interactor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001030145.1NP_001025316.1  unconventional prefoldin RPB5 interactor 1

      See identical proteins and their annotated locations for NP_001025316.1

      Status: PROVISIONAL

      Source sequence(s)
      BC096800
      UniProtKB/TrEMBL
      Q4V9N5
      Related
      ENSDARP00000122374.1, ENSDART00000132249.2
      Conserved Domains (1) summary
      cl09111
      Location:33133
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      14693723..14705821
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)