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    HGD homogentisate 1,2-dioxygenase [ Canis lupus familiaris (dog) ]

    Gene ID: 478578, updated on 5-Mar-2024

    Summary

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    Official Symbol
    HGDprovided by VGNC
    Official Full Name
    homogentisate 1,2-dioxygenaseprovided by VGNC
    Primary source
    VGNC:VGNC:41673
    See related
    Ensembl:ENSCAFG00845018928
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See HGD in Genome Data Viewer
    Location:
    chromosome: 33
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 33 NC_051837.1 (24305826..24347869, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 33 NC_006615.4 (24095501..24137233, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 33 NC_049254.1 (24711359..24753085, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 33 NC_049293.1 (24106833..24148576, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 33 NC_049774.1 (24146893..24188831, complement)

    Chromosome 33 - NC_051837.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S15a-like Neighboring gene uncharacterized LOC102151423 Neighboring gene uncharacterized LOC119867336 Neighboring gene NADH:ubiquinone oxidoreductase subunit B4 Neighboring gene general transcription factor IIE subunit 1 Neighboring gene RAB, member of RAS oncogene family like 3 Neighboring gene syntaxin binding protein 5L Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables homogentisate 1,2-dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in L-phenylalanine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tyrosine metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    homogentisate 1,2-dioxygenase
    Names
    homogentisate 1,2-dioxygenase (homogentisate oxidase)
    XP_038301006.1
    XP_038301007.1
    XP_038318414.1
    XP_038375267.1
    XP_038375268.1
    XP_038438889.1
    XP_038438890.1
    XP_038503285.1
    XP_535754.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051837.1 Reference ROS_Cfam_1.0

      Range
      24305826..24347869 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038445079.1 → XP_038301007.1  homogentisate 1,2-dioxygenase isoform X2

      UniProtKB/TrEMBL
      A0A8C0K0R5, A0A8I3P921, A0A8I3PDU0
      Related
      ENSCAFP00845026301.1, ENSCAFT00845033595.1
      Conserved Domains (1) summary
      TIGR01015
      Location:3 → 434
      hmgA; homogentisate 1,2-dioxygenase

    2. XM_038445078.1 → XP_038301006.1  homogentisate 1,2-dioxygenase isoform X1

      UniProtKB/TrEMBL
      A0A8I3P3K4, A0A8I3PDU0
      Related
      ENSCAFP00845026413.1, ENSCAFT00845033745.1
      Conserved Domains (1) summary
      TIGR01015
      Location:23 → 451
      hmgA; homogentisate 1,2-dioxygenase

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049293.1 Alternate UMICH_Zoey_3.1

      Range
      24106833..24148576 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038519340.1 → XP_038375268.1  homogentisate 1,2-dioxygenase isoform X2

    2. XM_038519339.1 → XP_038375267.1  homogentisate 1,2-dioxygenase isoform X1

      Conserved Domains (1) summary
      TIGR01015
      Location:23 → 451
      hmgA; homogentisate 1,2-dioxygenase

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049774.1 Alternate UNSW_CanFamBas_1.0

      Range
      24146893..24188831 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038647357.1 → XP_038503285.1  homogentisate 1,2-dioxygenase isoform X2

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049254.1 Alternate UU_Cfam_GSD_1.0

      Range
      24711359..24753085 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038582962.1 → XP_038438890.1  homogentisate 1,2-dioxygenase isoform X2

      UniProtKB/TrEMBL
      A0A8C0K0R5, A0A8C0MZ30, A0A8P0NDB6

    2. XM_038582961.1 → XP_038438889.1  homogentisate 1,2-dioxygenase isoform X1

      UniProtKB/TrEMBL
      A0A8C0MSI4, A0A8C0T7H5, A0A8P0TAM0
      Conserved Domains (1) summary
      TIGR01015
      Location:23 → 451
      hmgA; homogentisate 1,2-dioxygenase

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006615.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      24095501..24137233 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_535754.7 → XP_535754.3  homogentisate 1,2-dioxygenase isoform X2

      UniProtKB/TrEMBL
      A0A8C0K0R5, A0A8C0MZ30, A0A8P0NDB6
      Conserved Domains (1) summary
      TIGR01015
      Location:3 → 434
      hmgA; homogentisate 1,2-dioxygenase

    2. XM_038462486.1 → XP_038318414.1  homogentisate 1,2-dioxygenase isoform X1

      UniProtKB/TrEMBL
      A0A8C0MSI4, A0A8C0T7H5, A0A8P0TAM0
      Conserved Domains (1) summary
      TIGR01015
      Location:23 → 451
      hmgA; homogentisate 1,2-dioxygenase
    Nucleotide Protein
    Heading Accession and Version

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