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    LCP1 lymphocyte cytosolic protein 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 476921, updated on 5-Mar-2024

    Summary

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    Official Symbol
    LCP1provided by VGNC
    Official Full Name
    lymphocyte cytosolic protein 1provided by VGNC
    Primary source
    VGNC:VGNC:42614
    See related
    Ensembl:ENSCAFG00845008232
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See LCP1 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 22 NC_051826.1 (5070372..5176432)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 22 NC_006604.4 (4965424..5047265)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 22 NC_049243.1 (4921102..5027186)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 22 NC_049282.1 (4852728..4958773)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 22 NC_049763.1 (4916029..5022003)

    Chromosome 22 - NC_051826.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119865177 Neighboring gene uncharacterized LOC119865178 Neighboring gene leucine rich repeat containing 63 Neighboring gene non-histone chromosomal protein HMG-17-like Neighboring gene uncharacterized LOC102154865 Neighboring gene carboxypeptidase B2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament bundle assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actin filament network formation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin filament IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in actin filament bundle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    plastin-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051826.1 Reference ROS_Cfam_1.0

      Range
      5070372..5176432
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038430957.1 → XP_038286885.1  plastin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0L708, A0A8I3NAM1, A0A8P0PAY9
      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    2. XM_038430961.1 → XP_038286889.1  plastin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0L708, A0A8I3NAM1, A0A8P0PAY9
      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    3. XM_038430958.1 → XP_038286886.1  plastin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0L708, A0A8I3NAM1, A0A8P0PAY9
      Related
      ENSCAFP00845011301.1, ENSCAFT00845014584.1
      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    4. XM_038430959.1 → XP_038286887.1  plastin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0L708, A0A8I3NAM1, A0A8P0PAY9
      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    5. XM_038430960.1 → XP_038286888.1  plastin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0L708, A0A8I3NAM1, A0A8P0PAY9
      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    6. XM_038430956.1 → XP_038286884.1  plastin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L708
      Conserved Domains (5) summary
      cd00051
      Location:63 → 129
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:148 → 292
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:301 → 425
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:561 → 675
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:424 → 557
      CH_SF; calponin homology (CH) domain superfamily

    RNA

    1. XR_005299244.1 RNA Sequence

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049282.1 Alternate UMICH_Zoey_3.1

      Range
      4852728..4958773
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038506337.1 → XP_038362265.1  plastin-2 isoform X1

      Conserved Domains (5) summary
      cd00051
      Location:63 → 129
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:148 → 292
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:301 → 425
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:561 → 675
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:424 → 557
      CH_SF; calponin homology (CH) domain superfamily

    2. XM_038506339.1 → XP_038362267.1  plastin-2 isoform X2

      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    3. XM_038506342.1 → XP_038362270.1  plastin-2 isoform X2

      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    4. XM_038506343.1 → XP_038362271.1  plastin-2 isoform X2

      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    5. XM_038506338.1 → XP_038362266.1  plastin-2 isoform X1

      Conserved Domains (5) summary
      cd00051
      Location:63 → 129
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:148 → 292
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:301 → 425
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:561 → 675
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:424 → 557
      CH_SF; calponin homology (CH) domain superfamily

    6. XM_038506340.1 → XP_038362268.1  plastin-2 isoform X2

      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    7. XM_038506341.1 → XP_038362269.1  plastin-2 isoform X2

      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    RNA

    1. XR_005342354.1 RNA Sequence

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049763.1 Alternate UNSW_CanFamBas_1.0

      Range
      4916029..5022003
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038633704.1 → XP_038489632.1  plastin-2 isoform X2

      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    2. XM_038633709.1 → XP_038489637.1  plastin-2 isoform X2

      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    3. XM_038633705.1 → XP_038489633.1  plastin-2 isoform X2

      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    4. XM_038633706.1 → XP_038489634.1  plastin-2 isoform X2

      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    5. XM_038633708.1 → XP_038489636.1  plastin-2 isoform X2

      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    6. XM_038633703.1 → XP_038489631.1  plastin-2 isoform X1

      Conserved Domains (5) summary
      cd00051
      Location:63 → 129
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:148 → 292
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:301 → 425
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:561 → 675
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:424 → 557
      CH_SF; calponin homology (CH) domain superfamily

    RNA

    1. XR_005410139.1 RNA Sequence

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049243.1 Alternate UU_Cfam_GSD_1.0

      Range
      4921102..5027186
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038569538.1 → XP_038425466.1  plastin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L708
      Conserved Domains (5) summary
      cd00051
      Location:63 → 129
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:148 → 292
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:301 → 425
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:561 → 675
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:424 → 557
      CH_SF; calponin homology (CH) domain superfamily

    2. XM_038569540.1 → XP_038425468.1  plastin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0L708, A0A8I3NAM1, A0A8P0PAY9
      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    3. XM_038569543.1 → XP_038425471.1  plastin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0L708, A0A8I3NAM1, A0A8P0PAY9
      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    4. XM_038569544.1 → XP_038425472.1  plastin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0L708, A0A8I3NAM1, A0A8P0PAY9
      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    5. XM_038569539.1 → XP_038425467.1  plastin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L708
      Conserved Domains (5) summary
      cd00051
      Location:63 → 129
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:148 → 292
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:301 → 425
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:561 → 675
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:424 → 557
      CH_SF; calponin homology (CH) domain superfamily

    6. XM_038569541.1 → XP_038425469.1  plastin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0L708, A0A8I3NAM1, A0A8P0PAY9
      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    7. XM_038569542.1 → XP_038425470.1  plastin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0L708, A0A8I3NAM1, A0A8P0PAY9
      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    RNA

    1. XR_005376213.1 RNA Sequence

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006604.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      4965424..5047265
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038456556.1 → XP_038312484.1  plastin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0L708, A0A8I3NAM1, A0A8P0PAY9
      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    2. XM_022408296.2 → XP_022264004.1  plastin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L708
      Conserved Domains (5) summary
      cd00051
      Location:63 → 129
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:148 → 292
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:301 → 425
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:561 → 675
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:424 → 557
      CH_SF; calponin homology (CH) domain superfamily

    3. XM_038456555.1 → XP_038312483.1  plastin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0L708, A0A8I3NAM1, A0A8P0PAY9
      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    4. XM_038456554.1 → XP_038312482.1  plastin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L708
      Conserved Domains (5) summary
      cd00051
      Location:63 → 129
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:148 → 292
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:301 → 425
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:561 → 675
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:424 → 557
      CH_SF; calponin homology (CH) domain superfamily

    5. XM_005633885.4 → XP_005633942.1  plastin-2 isoform X2

      See identical proteins and their annotated locations for XP_005633942.1

      UniProtKB/TrEMBL
      A0A8C0L708, A0A8I3NAM1, A0A8P0PAY9
      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    RNA

    1. XR_005313323.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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