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    CBX5 chromobox 5 [ Canis lupus familiaris (dog) ]

    Gene ID: 477593, updated on 5-Mar-2024

    Summary

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    Official Symbol
    CBX5provided by VGNC
    Official Full Name
    chromobox 5provided by VGNC
    Primary source
    VGNC:VGNC:38767
    See related
    Ensembl:ENSCAFG00845017851
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See CBX5 in Genome Data Viewer
    Location:
    chromosome: 27
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 27 NC_051831.1 (1017407..1054956)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 27 NC_006609.4 (45197396..45234943, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 27 NC_049248.1 (45601201..45638748, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 27 NC_049287.1 (1036373..1073913)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 27 NC_049768.1 (1017977..1055663)

    Chromosome 27 - NC_051831.1Genomic Context describing neighboring genes Neighboring gene nuclear factor, erythroid 2 Neighboring gene heterogeneous nuclear ribonucleoprotein A1 Neighboring gene uncharacterized LOC119866354 Neighboring gene single-strand-selective monofunctional uracil-DNA glycosylase 1 Neighboring gene uncharacterized LOC111092898

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables chromatin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables methylated histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromatin organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of pericentric heterochromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    chromobox protein homolog 5
    Names
    chromobox homolog 5 (HP1 alpha homolog, Drosophila)

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051831.1 Reference ROS_Cfam_1.0

      Range
      1017407..1054956
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038438000.1 → XP_038293928.1  chromobox protein homolog 5 isoform X2

      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:115 → 172
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    2. XM_038437997.1 → XP_038293925.1  chromobox protein homolog 5 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L8W2, A0A8C0RTW7, A0A8I3P9H2
      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:116 → 173
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    3. XM_038437996.1 → XP_038293924.1  chromobox protein homolog 5 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L8W2, A0A8C0RTW7, A0A8I3P9H2
      Related
      ENSCAFP00845024733.1, ENSCAFT00845031596.1
      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:116 → 173
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    4. XM_038437998.1 → XP_038293926.1  chromobox protein homolog 5 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L8W2, A0A8C0RTW7, A0A8I3P9H2
      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:116 → 173
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    5. XM_038437999.1 → XP_038293927.1  chromobox protein homolog 5 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L8W2, A0A8C0RTW7, A0A8I3P9H2
      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:116 → 173
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049287.1 Alternate UMICH_Zoey_3.1

      Range
      1036373..1073913
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038512706.1 → XP_038368634.1  chromobox protein homolog 5 isoform X2

      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:115 → 172
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    2. XM_038512703.1 → XP_038368631.1  chromobox protein homolog 5 isoform X1

      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:116 → 173
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    3. XM_038512702.1 → XP_038368630.1  chromobox protein homolog 5 isoform X1

      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:116 → 173
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    4. XM_038512704.1 → XP_038368632.1  chromobox protein homolog 5 isoform X1

      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:116 → 173
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    5. XM_038512705.1 → XP_038368633.1  chromobox protein homolog 5 isoform X1

      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:116 → 173
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049768.1 Alternate UNSW_CanFamBas_1.0

      Range
      1017977..1055663
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038640459.1 → XP_038496387.1  chromobox protein homolog 5 isoform X2

      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:115 → 172
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    2. XM_038640456.1 → XP_038496384.1  chromobox protein homolog 5 isoform X1

      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:116 → 173
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    3. XM_038640455.1 → XP_038496383.1  chromobox protein homolog 5 isoform X1

      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:116 → 173
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    4. XM_038640457.1 → XP_038496385.1  chromobox protein homolog 5 isoform X1

      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:116 → 173
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    5. XM_038640458.1 → XP_038496386.1  chromobox protein homolog 5 isoform X1

      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:116 → 173
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049248.1 Alternate UU_Cfam_GSD_1.0

      Range
      45601201..45638748 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038577847.1 → XP_038433775.1  chromobox protein homolog 5 isoform X2

      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:115 → 172
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    2. XM_038577844.1 → XP_038433772.1  chromobox protein homolog 5 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L8W2, A0A8C0RTW7, A0A8I3P9H2
      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:116 → 173
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    3. XM_038577843.1 → XP_038433771.1  chromobox protein homolog 5 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L8W2, A0A8C0RTW7, A0A8I3P9H2
      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:116 → 173
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    4. XM_038577845.1 → XP_038433773.1  chromobox protein homolog 5 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L8W2, A0A8C0RTW7, A0A8I3P9H2
      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:116 → 173
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    5. XM_038577846.1 → XP_038433774.1  chromobox protein homolog 5 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L8W2, A0A8C0RTW7, A0A8I3P9H2
      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:116 → 173
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006609.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      45197396..45234943 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038460194.1 → XP_038316122.1  chromobox protein homolog 5 isoform X2

      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:115 → 172
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    2. XM_005636747.4 → XP_005636804.1  chromobox protein homolog 5 isoform X1

      See identical proteins and their annotated locations for XP_005636804.1

      UniProtKB/TrEMBL
      A0A8C0L8W2, A0A8C0RTW7, A0A8I3P9H2
      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:116 → 173
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    3. XM_534787.7 → XP_534787.3  chromobox protein homolog 5 isoform X1

      See identical proteins and their annotated locations for XP_534787.3

      UniProtKB/TrEMBL
      A0A8C0L8W2, A0A8C0RTW7, A0A8I3P9H2
      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:116 → 173
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    4. XM_003433566.5 → XP_003433614.1  chromobox protein homolog 5 isoform X1

      See identical proteins and their annotated locations for XP_003433614.1

      UniProtKB/TrEMBL
      A0A8C0L8W2, A0A8C0RTW7, A0A8I3P9H2
      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:116 → 173
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha

    5. XM_014108450.3 → XP_013963925.1  chromobox protein homolog 5 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L8W2, A0A8C0RTW7, A0A8I3P9H2
      Conserved Domains (2) summary
      cd18651
      Location:19 → 68
      CD_HP1alpha_Cbx5; chromodomain of heterochromatin protein 1 homolog alpha
      cd18655
      Location:116 → 173
      CSD_HP1alpha_Cbx5; chromo shadow domain of heterochromatin protein 1 homolog alpha
    Nucleotide Protein
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