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    HOGA1 4-hydroxy-2-oxoglutarate aldolase 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 608755, updated on 5-Mar-2024

    Summary

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    Official Symbol
    HOGA1provided by VGNC
    Official Full Name
    4-hydroxy-2-oxoglutarate aldolase 1provided by VGNC
    Primary source
    VGNC:VGNC:41736
    See related
    Ensembl:ENSCAFG00845029887
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    NPL2; DHDPSL
    Orthologs
    human mouse all
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    Genomic context

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    See HOGA1 in Genome Data Viewer
    Location:
    chromosome: 28
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 28 NC_051832.1 (11173637..11200481)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 28 NC_006610.4 (11033727..11060294)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 28 NC_049249.1 (11035386..11061987)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 28 NC_049288.1 (10834716..10859086)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 28 NC_049769.1 (10895424..10922168)

    Chromosome 28 - NC_051832.1Genomic Context describing neighboring genes Neighboring gene ubiquitin domain containing 1 Neighboring gene uncharacterized LOC119866569 Neighboring gene ankyrin repeat domain 2 Neighboring gene chromosome 28 C10orf62 homolog Neighboring gene MORN repeat containing 4 Neighboring gene phosphatidylinositol 4-kinase type 2 alpha Neighboring gene 40S ribosomal protein SA-like Neighboring gene arginine vasopressin induced 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 4-hydroxy-tetrahydrodipicolinate synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables N-acetylneuraminate lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in N-acetylneuraminate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    probable 4-hydroxy-2-oxoglutarate aldolase, mitochondrial; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial; LOW QUALITY PROTEIN: 4-hydroxy-2-oxoglutarate aldolase, mitochondrial
    XP_022267351.2
    XP_038296114.1
    XP_038296115.1
    XP_038316297.1
    XP_038370727.1
    XP_038434358.1
    XP_038434359.1
    XP_038498522.1
    XP_038498523.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051832.1 Reference ROS_Cfam_1.0

      Range
      11173637..11200481
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038440187.1 → XP_038296115.1  4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A8C0TUY7
      Conserved Domains (1) summary
      cd00408
      Location:38 → 278
      DHDPS-like; Dihydrodipicolinate synthase family

    2. XM_038440186.1 → XP_038296114.1  4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8C0RR42, A0A8C0TUY7, A0A8I3Q9P3
      Related
      ENSCAFP00845041562.1, ENSCAFT00845052936.1
      Conserved Domains (1) summary
      cd00408
      Location:38 → 321
      DHDPS-like; Dihydrodipicolinate synthase family

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049288.1 Alternate UMICH_Zoey_3.1

      Range
      10834716..10859086
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038514799.1 → XP_038370727.1  LOW QUALITY PROTEIN: 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049769.1 Alternate UNSW_CanFamBas_1.0

      Range
      10895424..10922168
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038642595.1 → XP_038498523.1  4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X2

      Conserved Domains (1) summary
      cd00408
      Location:38 → 278
      DHDPS-like; Dihydrodipicolinate synthase family

    2. XM_038642594.1 → XP_038498522.1  4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1

      Conserved Domains (1) summary
      cd00408
      Location:38 → 321
      DHDPS-like; Dihydrodipicolinate synthase family

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049249.1 Alternate UU_Cfam_GSD_1.0

      Range
      11035386..11061987
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038578431.1 → XP_038434359.1  4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A8C0TUY7
      Conserved Domains (1) summary
      cd00408
      Location:38 → 278
      DHDPS-like; Dihydrodipicolinate synthase family

    2. XM_038578430.1 → XP_038434358.1  4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8C0RR42, A0A8C0TUY7, A0A8I3Q9P3
      Conserved Domains (1) summary
      cd00408
      Location:38 → 321
      DHDPS-like; Dihydrodipicolinate synthase family

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006610.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      11033727..11060294
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038460369.1 → XP_038316297.1  4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A8C0TUY7
      Conserved Domains (1) summary
      cd00408
      Location:38 → 278
      DHDPS-like; Dihydrodipicolinate synthase family

    2. XM_022411643.2 → XP_022267351.2  4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8C0RR42, A0A8C0TUY7, A0A8I3Q9P3
      Conserved Domains (1) summary
      cd00408
      Location:38 → 321
      DHDPS-like; Dihydrodipicolinate synthase family
    Nucleotide Protein
    Heading Accession and Version

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