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    CYP8B1 cytochrome P450 family 8 subfamily B member 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 485619, updated on 5-Mar-2024

    Summary

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    Official Symbol
    CYP8B1provided by VGNC
    Official Full Name
    cytochrome P450 family 8 subfamily B member 1provided by VGNC
    Primary source
    VGNC:VGNC:50380
    See related
    Ensembl:ENSCAFG00845021247
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See CYP8B1 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 23 NC_051827.1 (12255398..12258673, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 23 NC_006605.4 (11939545..11942820, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 23 NC_049244.1 (12202997..12206280, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 23 NC_049283.1 (12057378..12060653, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 23 NC_049764.1 (12199554..12202829, complement)

    Chromosome 23 - NC_051827.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L31 pseudogene Neighboring gene HIG1 hypoxia inducible domain family member 1A Neighboring gene atypical chemokine receptor 2 Neighboring gene zinc finger protein 662 Neighboring gene golgi associated kinase 1A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sterol 12-alpha-hydroxylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase; LOW QUALITY PROTEIN: 5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051827.1 Reference ROS_Cfam_1.0

      Range
      12255398..12258673 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038432041.1 → XP_038287969.1  5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase

      UniProtKB/TrEMBL
      A0A8C0Z062, A0A8I3PFY5
      Related
      ENSCAFP00845029367.1, ENSCAFT00845037483.1
      Conserved Domains (1) summary
      cl41757
      Location:57 → 493
      cytochrome_P450; cytochrome P450 (CYP) superfamily

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049283.1 Alternate UMICH_Zoey_3.1

      Range
      12057378..12060653 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038507349.1 → XP_038363277.1  5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase

      Conserved Domains (1) summary
      cl41757
      Location:57 → 493
      cytochrome_P450; cytochrome P450 (CYP) superfamily

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049764.1 Alternate UNSW_CanFamBas_1.0

      Range
      12199554..12202829 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038634769.1 → XP_038490697.1  5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase

      Conserved Domains (1) summary
      cl41757
      Location:57 → 493
      cytochrome_P450; cytochrome P450 (CYP) superfamily

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049244.1 Alternate UU_Cfam_GSD_1.0

      Range
      12202997..12206280 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038570587.1 → XP_038426515.1  LOW QUALITY PROTEIN: 5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase

      UniProtKB/TrEMBL
      A0A8C0Z062, A0A8I3PFY5
      Conserved Domains (1) summary
      cl41757
      Location:57 → 493
      cytochrome_P450; cytochrome P450 (CYP) superfamily

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006605.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      11939545..11942820 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005634313.4 → XP_005634370.1  5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase

      UniProtKB/TrEMBL
      A0A8C0LND4, A0A8C0NR21, A0A8P0N817
      Conserved Domains (1) summary
      cl12078
      Location:38 → 493
      p450; Cytochrome P450
    Nucleotide Protein
    Heading Accession and Version

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