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    Adra1a adrenoceptor alpha 1A [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101712485, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Adra1a
    Gene description
    adrenoceptor alpha 1A
    See related
    Ensembl:ENSHGLG00000009186
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Orthologs
    human mouse all
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    Genomic context

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    See Adra1a in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624758.1 (21557161..21665432, complement)

    NW_004624758.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101711525 Neighboring gene coiled-coil domain-containing protein 77-like Neighboring gene polypeptide N-acetylgalactosaminyltransferase 1 pseudogene Neighboring gene eukaryotic translation initiation factor 5-like Neighboring gene TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 pseudogene Neighboring gene uncharacterized LOC110349991

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624758 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables alpha1-adrenergic receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adenylate cyclase-activating adrenergic receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-cell signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cytosolic calcium ion concentration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cardiac muscle contraction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of vasoconstriction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    alpha-1A adrenergic receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624758.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      21557161..21665432 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021261311.1 → XP_021116970.1  alpha-1A adrenergic receptor isoform X1

      UniProtKB/TrEMBL
      A0A0P6JGA2
      Conserved Domains (1) summary
      cd15325
      Location:27 → 337
      7tmA_alpha1A_AR; alpha-1 adrenergic receptors subtype A, member of the class A family of seven-transmembrane G protein-coupled receptors

    2. XM_004848377.2 → XP_004848434.1  alpha-1A adrenergic receptor isoform X1

      UniProtKB/TrEMBL
      A0A0P6JGA2
      Related
      ENSHGLP00000012852.1, ENSHGLT00000012989.1
      Conserved Domains (1) summary
      cd15325
      Location:27 → 337
      7tmA_alpha1A_AR; alpha-1 adrenergic receptors subtype A, member of the class A family of seven-transmembrane G protein-coupled receptors

    3. XM_013073430.2 → XP_012928884.1  alpha-1A adrenergic receptor isoform X2

      Conserved Domains (2) summary
      pfam00001
      Location:43 → 300
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:37 → 141
      7tm_4; Olfactory receptor
    Nucleotide Protein
    Heading Accession and Version

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