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    ntrk2a neurotrophic tyrosine kinase, receptor, type 2a [ Oryzias latipes (Japanese medaka) ]

    Gene ID: 101172248, updated on 11-Apr-2024

    Summary

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    Gene symbol
    ntrk2a
    Gene description
    neurotrophic tyrosine kinase, receptor, type 2a
    See related
    EnsemblRapid:ENSORLG00000005227
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryzias latipes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae; Oryzias
    Also known as
    ntrk2
    Orthologs
    human zebrafish all
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    Genomic context

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    See ntrk2a in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    103 current ASM223467v1 (GCF_002234675.1) 9 NC_019867.2 (10832626..10915564)
    102 previous assembly ASM31367v1 (GCF_000313675.1) 9 NC_019867.1 (10123904..10208868)

    Chromosome 9 - NC_019867.2Genomic Context describing neighboring genes Neighboring gene RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae) Neighboring gene solute carrier family 28 member 3 Neighboring gene ATP/GTP binding carboxypeptidase 1 Neighboring gene N-alpha-acetyltransferase 35, NatC auxiliary subunit

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables brain-derived neurotrophic factor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables brain-derived neurotrophic factor receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to brain-derived neurotrophic factor stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in trans-synaptic signaling by neuropeptide, modulating synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    BDNF/NT-3 growth factors receptor
    Names
    neurotrophic receptor tyrosine kinase 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Oryzias latipes Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM223467v1 Primary Assembly

    Genomic

    1. NC_019867.2 Reference ASM223467v1 Primary Assembly

      Range
      10832626..10915564
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_020705849.1 → XP_020561508.1  BDNF/NT-3 growth factors receptor isoform X1

      UniProtKB/TrEMBL
      H2LKP1
      Related
      ENSORLP00000077624.1, ENSORLT00000102080.1
      Conserved Domains (5) summary
      sd00031
      Location:104 → 127
      LRR_1; leucine-rich repeat [structural motif]
      pfam13855
      Location:103 → 161
      LRR_8; Leucine rich repeat
      cl11960
      Location:309 → 387
      Ig; Immunoglobulin domain
      cl21453
      Location:518 → 809
      PKc_like; Protein Kinases, catalytic domain
      cl28434
      Location:206 → 289
      I-set; Immunoglobulin I-set domain

    2. XM_020705850.2 → XP_020561509.1  BDNF/NT-3 growth factors receptor isoform X2

      UniProtKB/TrEMBL
      H2LKP1
      Conserved Domains (5) summary
      sd00031
      Location:104 → 127
      LRR_1; leucine-rich repeat [structural motif]
      pfam13855
      Location:103 → 161
      LRR_8; Leucine rich repeat
      cl11960
      Location:309 → 387
      Ig; Immunoglobulin domain
      cl21453
      Location:518 → 807
      PKc_like; Protein Kinases, catalytic domain
      cl28434
      Location:206 → 289
      I-set; Immunoglobulin I-set domain
    Nucleotide Protein
    Heading Accession and Version

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