ddx25.L DEAD-box helicase 25 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: ddx25.L
Official Full Name: DEAD-box helicase 25 L homeolog
Primary source: Xenbase:XB-GENE-958142
Locus tag: XELAEV_18035291mg
See related: EnsemblRapid:ENSXLAG00005015916
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: grth; ddx25; deadsouth
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Genomic context

Location:: chromosome: 7L

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	7L	NC_054383.1 (76005383..76043055)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	7L	NC_030736.1 (67449732..67487334)

Chromosome 7L - NC_054383.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

the predominant expression of DEADSouth mRNA in the PGCs is ensured by multiple mechanisms including zygotic expression and prohibition from miR-427-mediated degradation.
Title: Restriction of the Xenopus DEADSouth mRNA to the primordial germ cells is ensured by multiple mechanisms.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	ISS Inferred from Sequence or Structural Similarity more info
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables RNA binding	ISS Inferred from Sequence or Structural Similarity more info
enables RNA helicase activity	IEA Inferred from Electronic Annotation more info
enables RNA helicase activity	ISS Inferred from Sequence or Structural Similarity more info
enables helicase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
acts_upstream_of_or_within poly(A)+ mRNA export from nucleus	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in chromatoid body	ISS Inferred from Sequence or Structural Similarity more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic stress granule	IEA Inferred from Electronic Annotation more info
located_in mitochondrial cloud	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in pole plasm	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: ATP-dependent RNA helicase DDX25

Names: DEAD (Asp-Glu-Ala-Asp) box helicase 25; DEAD (Asp-Glu-Ala-Asp) box polypeptide 25; DEAD box protein 25; DEADSouth RNA helicase; RNA helicase DEADSouth; xcat3

NP_001082017.1

EC 3.6.4.13

XP_041424338.1

EC 3.6.4.13

XP_041424339.1

EC 3.6.4.13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001088548.1 → NP_001082017.1 ATP-dependent RNA helicase DDX25

See identical proteins and their annotated locations for NP_001082017.1

Status: PROVISIONAL

Source sequence(s)

AF190623

UniProtKB/Swiss-Prot

Q9DGP9

UniProtKB/TrEMBL

A0A974HBX6, B1WBD2

Related

ENSXLAP00005046937.1, ENSXLAT00005048041.1

Conserved Domains (3) summary

PTZ00424
Location:96 → 476

PTZ00424; helicase 45; Provisional

cd00079
Location:311 → 447

HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...

cl21455
Location:99 → 301

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054383.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

76005383..76043055

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041568405.1 → XP_041424339.1 ATP-dependent RNA helicase DDX25 isoform X2

UniProtKB/TrEMBL

A0A8J1L5W8

Related

ENSXLAP00005046975.1, ENSXLAT00005048079.1

Conserved Domains (2) summary

cd18787
Location:281 → 417

SF2_C_DEAD; C-terminal helicase domain of the DEAD box helicases

cl28899
Location:80 → 277

DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily
XM_041568404.1 → XP_041424338.1 ATP-dependent RNA helicase DDX25 isoform X1

UniProtKB/TrEMBL

A0A8J1L488

Related

ENSXLAP00005046956.1, ENSXLAT00005048060.1

Conserved Domains (2) summary

cd18787
Location:297 → 433

SF2_C_DEAD; C-terminal helicase domain of the DEAD box helicases

cd18048
Location:65 → 293

DEADc_DDX25; DEAD-box helicase domain of DEAD box protein 25