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| Status |
Public on Oct 01, 2018 |
| Title |
Expression data from different levels of ANA in HIV+ people |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Different focal adhesions, gap junction, adherens junction, and tight junction, TLR signaling pathway were seen when compared the HIV+ high ANA (anti-nuclear antibodies) group with low ANA group
We used microarrays to detail the global programme of gene expression underlying cellularisation and identified distinct classes of up-regulated genes during this process.
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| Overall design |
HIV+ subject received the influenza vaccine, we draw the blood at the D0 and D7 of vaccination. Total RNA from purified B cells of PBMC was extracted using RNeasy Micro kit . Affymetrix Human GeneChip U133 Plus 2.0 Array was used for RNA hybridization and labeling assay. We used the gene expression to compare the gene expression of high ANA HIV+ subjects versus and low ANA subjects.
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| Contributor(s) |
Jiang W, Luo Z |
| Citation(s) |
30764863 |
| Submission date |
Jul 18, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Zhenwu Luo |
| Organization name |
Medical University of South Carolina
|
| Department |
Immunology & Microbiology
|
| Street address |
173 Ashley Ave
|
| City |
Charleston |
| State/province |
SC |
| ZIP/Postal code |
29407 |
| Country |
USA |
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| Platforms (1) |
| GPL16686 |
[HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version] |
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| Samples (28)
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| Relations |
| BioProject |
PRJNA394897 |
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