|
| Status |
Public on May 20, 2022 |
| Title |
Identifying miR-139 targets in motor neurons |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We sought to investigate changes in expression levels of RNAs in response to miR-139 overexpression in human iPSC-derived motor neurons
Motor neurons were differentiated from FUS H517Q iPSCs and transduced with AAVs expressing miR-139 or controls hairpins. RNA was harvested at day 34. We performed gene expression profiling analysis using data obtained from bulk RNA-seq.
|
| |
|
| Overall design |
Comparative gene expression profiling using RNA-seq analysis of miR-139 overexpression in FUS H517Q motor neurons.
|
| |
|
| Contributor(s) |
Hawkins S, Namboori S, Bhinge A |
| Citation(s) |
35750046 |
| Submission date |
May 17, 2022 |
| Last update date |
Aug 02, 2022 |
| Contact name |
Akshay Bhinge |
| E-mail(s) |
drabhinge@gmail.com
|
| Organization name |
Living Systems Institute, University of Exeter
|
| Department |
Medical School
|
| Street address |
Stocker Road
|
| City |
Exeter |
| ZIP/Postal code |
EX4 4QD |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
|
| Samples (6)
|
|
| This SubSeries is part of SuperSeries: |
| GSE203173 |
FUS H517Q and healthy iPSC-derived motor neurons |
|
| Relations |
| BioProject |
PRJNA838955 |
Less...
More...