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| Status |
Public on Mar 18, 2023 |
| Title |
High-throughput transcriptomics of Celf1 conditional knockout lens identifies downstream networks linked to cataract pathology |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Celf1 germline or conditional deletion mouse mutants exhibit fully penetrant lens defects including cataract. To gain insight into gene expression changes underlying these lens defects Differential Gene Expression analysis was performed for lenses obtained from control and Celf1 conditional deletion mutant mice.
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| Overall design |
Differential Gene Expression analysis of RNA-seq data from lens of P0 mice Celf1 cko or Control, from mixed background (C57BL/6J ; FVB) control (Celf1lacZKI/+)and mutant (Celf1cKO) mice was performed
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| Contributor(s) |
Siddam AD, Lachke SA |
| Citation(s) |
37048143 |
| Submission date |
Mar 14, 2023 |
| Last update date |
Oct 13, 2023 |
| Contact name |
Salil Anil Lachke |
| E-mail(s) |
salil@udel.edu
|
| Organization name |
University of Delaware
|
| Department |
Biological Sciences
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| Street address |
351 Wolf Hall, University of Delaware
|
| City |
Newark |
| State/province |
Delaware |
| ZIP/Postal code |
19716 |
| Country |
USA |
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| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA944591 |
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