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Series GSE28860 Query DataSets for GSE28860
Status Public on Oct 10, 2012
Title WU-BC 3, 4, and 5 PAM50 Subtypes with Passage and Gene Expression Comparison Between Xenografts and Primary Tumors
Platform organism Homo sapiens
Sample organisms Homo sapiens; Mus musculus
Experiment type Expression profiling by array
Summary Whole genome expression studies were performed on Xenograft panels with multiple passages from 3 different patient tumors. We assessed the global gene expression concordance from passages to passage and from passage to primary tumor when available and performed PAM50 subtype classification. These results were examined within the context of 40 PAM50 prototype experiments.
 
Overall design Thirteen experiments representing different tumor passages from WU-BC 3, 4, and 5 were compared using unsupervised hierarchical clustering and PAM50 Subtype Classification. These experiments were analyzed within the context of previously published PAM50 Prototypes (GSE26082).
 
Contributor(s) Ma CX, Cai S, Li S, Ryan CE, Guo Z, Lin L, Hoog JW, Goiffon RJ, Prat A, Aft RL, Ellis MJ, Piwnica-Worms H
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Submission date Apr 26, 2011
Last update date Dec 26, 2023
Contact name Cynthia Ma
E-mail(s) cynthiaxma@wustl.edu
Phone 3143628903
Organization name Washington University
Department Medical Oncology
Lab Dr. Cynthia Ma Lab
Street address 4515 Mckinley, 4515 Mckinley
City st louis
State/province Missouri
ZIP/Postal code 63627
Country USA
 
Platforms (1)
GPL6480 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version)
Samples (53)
GSM640379 Breast Cancer Array_Patient ID_15928_New Reference
GSM640380 Breast Cancer Array_Patient ID_10752
GSM640381 Breast Cancer Array_Patient ID_11726
Relations
BioProject PRJNA140693

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE28860_RAW.tar 804.2 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table
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