NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Sample GSM225409 Query DataSets for GSM225409
Status Public on Jan 03, 2008
Title 4-Chloroaniline 48h
Sample type RNA
 
Channel 1
Source name mRNA from zebrafish embryos that were exposed to 4-Chloroaniline 48h
Organism Danio rerio
Characteristics whole body mRNA
Strains: 200-800 zebrafish from AB*,AB2O2,AB2O2 Golden and AB2O2 Leo
whole body mRNA
Strains: 200-800 zebrafish from AB*,AB2O2,AB2O2 Golden and AB2O2 Leo
Biomaterial provider Fish Facility at the Institute of Toxicology and Genetics, Forschungszentrum Karlsruhe
Treatment protocol Acrylamide (CH2=CHCONH2), Aroclor 1254 (PCB), Arsenic(III) Oxide (As2O3), tBHQ (tert-Butylhydroquinone (CH3)3CC6H3-1,4-(OH)2), Cadmiumchloride (CdCl2.2H2O), 4-Chloroaniline (ClC6H4NH2), DDT (1,1-Bis-(4-Chlorphenyl)-2,2,2-Trichlorethan (ClC6H4)2CHCCl3), Lead (II)chloride (PbCl2), Methylmercurychloride (CH3ClHg), TCDD (2,3,7,8-Tetrachlorodibenzo-p-dioxin) and Valproic acid (CH3(CH2)4CO2H) were purchased from Sigma-Aldrich. Zebrafish wild type strains AB, ABO and Tuebingen were kept and bred. Embryos were grown in embryo medium (60 ug/ml Instant Ocean, Red Sea Fish Pharm Ltd.) Different numbers of embryos were exposed to the chemicals: between 4 to 24 hpf (600 embryos), 24 to 48 hpf (400 embryos) and 96 to 120 hpf (200 embryos). Embryo medium alone (Cd, Hg, Pb, As, VA, AA) or 0.2 % ethanol in embryo medium (tBHQ , 4CA, PCB, DDT) or 0.5% DMSO, 28mg/l toluene in embryo medium (TCDD) were used as vehicle controls. The toxin concentrations were adjusted in such a way that embryo death was minimal. The few dead embryos were discarded before preparation of RNA.
Growth protocol as described in Westerfield 1993
Extracted molecule polyA RNA
Extraction protocol 1) Total RNA was isolated using the Nucleospin RNA L Kit (Macherey-Nagel, Dueren, Germany). 2) mRNA was extracted with the Ambion Purist Kit (Austin, TX).
Label Cy5
Label protocol Labeled cDNA was synthesized from 1-2 ug mRNA using the Amersham direct cDNA labeling kit (Amersham Europe, Freiburg, Germany).
 
Channel 2
Source name mRNA from zebrafish embryos that were not exposed to a toxic environment
Organism Danio rerio
Characteristics Strains: 200-800 zebrafish from AB*,AB2O2,AB2O2 Golden and AB2O2 Leo
whole body mRNA
Biomaterial provider Fish Facility at the Institute of Toxicology and Genetics, Forschungszentrum Karlsruhe
Treatment protocol Acrylamide (CH2=CHCONH2), Aroclor 1254 (PCB), Arsenic(III) Oxide (As2O3), tBHQ (tert-Butylhydroquinone (CH3)3CC6H3-1,4-(OH)2), Cadmiumchloride (CdCl2.2H2O), 4-Chloroaniline (ClC6H4NH2), DDT (1,1-Bis-(4-Chlorphenyl)-2,2,2-Trichlorethan (ClC6H4)2CHCCl3), Lead (II)chloride (PbCl2), Methylmercurychloride (CH3ClHg), TCDD (2,3,7,8-Tetrachlorodibenzo-p-dioxin) and Valproic acid (CH3(CH2)4CO2H) were purchased from Sigma-Aldrich. Zebrafish wild type strains AB, ABO and Tuebingen were kept and bred. Embryos were grown in embryo medium (60 ug/ml Instant Ocean, Red Sea Fish Pharm Ltd.) Different numbers of embryos were exposed to the chemicals: between 4 to 24 hpf (600 embryos), 24 to 48 hpf (400 embryos) and 96 to 120 hpf (200 embryos). Embryo medium alone (Cd, Hg, Pb, As, VA, AA) or 0.2 % ethanol in embryo medium (tBHQ , 4CA, PCB, DDT) or 0.5% DMSO, 28mg/l toluene in embryo medium (TCDD) were used as vehicle controls. The toxin concentrations were adjusted in such a way that embryo death was minimal. The few dead embryos were discarded before preparation of RNA.
Growth protocol as described in Westerfield 1993
Extracted molecule polyA RNA
Extraction protocol 1) Total RNA was isolated using the Nucleospin RNA L Kit (Macherey-Nagel, Dueren, Germany).
2) mRNA was extracted with the Ambion Purist Kit (Austin, TX).
Label Cy3
Label protocol Labeled cDNA was synthesized from 1-2 ug mRNA using the Amersham direct cDNA labeling kit (Amersham Europe, Freiburg, Germany).
 
 
Hybridization protocol 1) Removal of unincorporated nucleotides over Microcon 30 spin columns (Millipore, Bedford, MA).
2) The concentrated probes were hybridized to the microarray in 1xDIG Easy-Hyb buffer (Hoffmann-La Roche, Basel, CH) overnight at 42 C.
3) Cover slips were removed from the slides by flushing with 4xSSC.
4) Slides were washed in pre-warmed wash buffer 1 (2xSSC, 0.1% SDS) for 5 minutes at 42 C.
5) Washing in buffer 2 (0.1xSSC, 0.1% SDS) for 10 minutes at room temperature.
6) Washing in 0.1xSSC four times for 1 min at room temperature.
7) The slides were briefly dipped into 0.01xSSC at room temperature.
8) Centrifugation for 7 min at 800 rpm in an Eppendorf 5810R centrifuge.
Scan protocol 1) Scanned on an GenePix 4000B dual-laser scanner from Molecular Devices
2) Both channels (532 nm for Cy3 and 635 nm for Cy5) were scanned in parallel
3) Data was stored as 16-bit TIFF files
4) The channels for Cy3 and Cy5 were balanced in each scan for approximately the same intensity profile.
5) Each array was scanned three times (low, medium and high scan) with different signal amplification factors (voltage settings of the photomultiplier tubes), but with the same laser power.
6) Raw data was retrieved with GenePix Pro 6.0 software from Axon Instruments .
7) Data processing was performed
8) The absolute intensity values span the range from 0 to 65536.
9) The scans were performed with a resolution of 10 um.
Description This file contains all technological and biological replicates (i.e. from the same and different biological source, repspectively) that were performed with this particular toxin at this particular concentration. The Dye-Swap Designe was utilised.
Data processing 1) Raw data are retrieved with GenePix 2) Quality control on spot level 3) Local background correction. 4) Averaging of the two spots for each gene. 5) Consensus signals are calculated from low, medium and high scan based on a Least Squares Algorithm. 6) Log transformation. 7) locally weighted regression smoother (LOESS). 8) Scaling to a common MAD. 9) t-test 10) adjustment of p-values for multiplicity 11) Quality control on array level.
 
Submission date Aug 29, 2007
Last update date Jan 02, 2008
Contact name Jessica Legradi
Organization name Karlsruhe Institute of Technology
Department Institute of Toxicology and Genomics ITG
Lab Straehle
Street address Hermann-von-Helmholtz-Platz 1
City Eggenstein-Leopoldshafen
State/province Baden-Wuerttemberg
ZIP/Postal code 76344
Country Germany
 
Platform ID GPL4603
Series (1)
GSE9357 biosensor-series

Data table header descriptions
ID_REF spot/gene id (numbered from 1-34992)
VALUE normalized log naturalis ratios (M or M.bar value) (test/reference)
res_A.bar averaged log naturalis average
res_M.var variance of VALUE
res_M.se standard error of VALUE
res_par.state1 Check for reliability of p-value and fold change: A.bar + 0.5 * M.bar
res_par.state2 Check for reliability of p-value and fold change: A.bar - 0.5 * M.bar
res_t test statistic of t-test for this gene
res_t.reg test statistic of regularized t-test for this gene
res_fc fold change
res_p.value p-value for t-test
res_p.adj adjusted p-value for t-test
res_wilcox.stat test statistic for wilcoxon test
res_p.value.adj.wil adjusted p-value for wilcoxon test
res_good.arrays numnber of good flags (after quality control) for this gene
res_comment1 Comment if FC is not reliable
res_comment2 Comment if t and regularized t-values are not reliable
norm_flag_Array1 flag if spot is good (1) or bad (0)
norm_flag_Array2
norm_flag_Array3
norm_flag_Array4
norm_flag_Array5
norm_flag_Array6
norm_R_Array1 Red signal after normalization
norm_R_Array2
norm_R_Array3
norm_R_Array4
norm_R_Array5
norm_R_Array6
norm_G_Array1 Green signal after normalization
norm_G_Array2
norm_G_Array3
norm_G_Array4
norm_G_Array5
norm_G_Array6
norm_M_Array1 M value after normalization
norm_M_Array2
norm_M_Array3
norm_M_Array4
norm_M_Array5
norm_M_Array6
norm_A_Array1 A value after normalization
norm_A_Array2
norm_A_Array3
norm_A_Array4
norm_A_Array5
norm_A_Array6
norm_C_Array1 Normalization constant that will be added to signal
norm_C_Array2
norm_C_Array3
norm_C_Array4
norm_C_Array5
norm_C_Array6
avg_R_Array1 Red channel value after averaging of scans
avg_R_Array2
avg_R_Array3
avg_R_Array4
avg_R_Array5
avg_R_Array6
avg_G_Array1 Green channel value after averaging of scans
avg_G_Array2
avg_G_Array3
avg_G_Array4
avg_G_Array5
avg_G_Array6
avg_flag_Array1 Flag (good/bad spot) value after averaging of scans
avg_flag_Array2
avg_flag_Array3
avg_flag_Array4
avg_flag_Array5
avg_flag_Array6

Data table
ID_REF VALUE res_A.bar res_M.var res_M.se res_par.state1 res_par.state2 res_t res_t.reg res_fc res_p.value res_p.adj res_wilcox.stat res_p.value.adj.wil res_good.arrays res_comment1 res_comment2 norm_flag_Array1 norm_flag_Array2 norm_flag_Array3 norm_flag_Array4 norm_flag_Array5 norm_flag_Array6 norm_R_Array1 norm_R_Array2 norm_R_Array3 norm_R_Array4 norm_R_Array5 norm_R_Array6 norm_G_Array1 norm_G_Array2 norm_G_Array3 norm_G_Array4 norm_G_Array5 norm_G_Array6 norm_M_Array1 norm_M_Array2 norm_M_Array3 norm_M_Array4 norm_M_Array5 norm_M_Array6 norm_A_Array1 norm_A_Array2 norm_A_Array3 norm_A_Array4 norm_A_Array5 norm_A_Array6 norm_C_Array1 norm_C_Array2 norm_C_Array3 norm_C_Array4 norm_C_Array5 norm_C_Array6 avg_R_Array1 avg_R_Array2 avg_R_Array3 avg_R_Array4 avg_R_Array5 avg_R_Array6 avg_G_Array1 avg_G_Array2 avg_G_Array3 avg_G_Array4 avg_G_Array5 avg_G_Array6 avg_flag_Array1 avg_flag_Array2 avg_flag_Array3 avg_flag_Array4 avg_flag_Array5 avg_flag_Array6
1 0.0312470295810991 6.28456457353177 0.0837191795388362 0.188512586879984 6.30018808832232 6.26894105874123 0.215986323721767 0.165755667026056 1.03174034279354 0.87889001652659 0.9392865267332 5 1 4 FALSE FALSE TRUE TRUE TRUE FALSE 5.47551978662023 5.9524065258913 6.71505485756078 5.82786913044201 5.97704926787072 6.15308888639413 -0.352349343821786 -0.0246427419794179 0.56196597116665 5.65169445853112 5.96472789688101 6.43407187197745 -0.499546225814047 -0.312697550251859 -0.475062355405091 186 329 650.358454831593 436 461 596.226163530842 FALSE FALSE TRUE TRUE TRUE FALSE
2 0.0540027933951881 7.22115022673936 0.0232047394779782 0.115220922217706 7.24815162343695 7.19414883004176 0.86836738180803 0.468689126555952 1.05548755054481 0.659014975369925 0.807658028094158 14 0.757038461538462 6 TRUE TRUE TRUE TRUE TRUE TRUE 6.51326333028772 6.87025267840861 6.65095125698787 6.6548344998572 8.01939560507594 7.67719545898583 6.45967107901601 6.80389814437074 6.93482051731137 6.83882162104863 7.52657101372311 7.58485196105173 0.053592251271707 0.0663545340378787 -0.283869260323503 -0.183987121191433 0.49282459135283 0.092343497934105 6.48646720465186 6.83707541138967 6.79288588714962 6.74682806045291 7.77298330939952 7.63102371001878 -0.411900078961013 0.0146738245931687 -0.424922279555478 -0.352412319166221 -0.379191258518413 -0.125009790078991 548.569121438864 970.284755420086 625.461712629977 651.077277026878 2514.42637703259 2027.76719741233 784.950861098621 894.765105679978 1270.64720145165 1113.23757222499 2244.33971421805 2095.10061214066 TRUE TRUE TRUE TRUE TRUE TRUE
3 0.362624450748182 6.4296958474593 0.0634809515046296 0.152700278788025 6.6110080728334 6.24838362208521 3.52542106647377 2.37474648786705 1.43709605753729 0.0635774725143856 0.128121568660642 21 0.0672509225092251 6 FALSE TRUE TRUE TRUE TRUE TRUE 5.8148215379688 5.99047315118917 5.81402242266089 7.0316559312765 6.0459334109276 6.27996337908144 6.09752091559556 6.35519949907127 6.8788761600111 6.70467909514533 -0.465141841112644 -0.107047764406386 -0.541177076410373 0.152779771265401 -0.658745684217728 6.04739245852512 6.04399703339237 6.08461096086608 6.9552660456438 6.37530625303646 0.0786052890292188 -0.427754732134222 -0.316061223682082 -0.443567093139430 -0.0149562749120391 348.669395526303 322.658918408086 286 906.755083747819 419.244915688924 513.197486262926 550.814604549959 674 1212.76688093713 822.342711884756 FALSE TRUE TRUE TRUE TRUE TRUE
4 -0.111776390965056 7.85231450719832 0.0438982145189099 0.122251885346041 7.79642631171579 7.90820270268085 -1.30677940094318 -0.914312205890861 -1.118262779025 0.402491718306542 0.599522825088648 6 0.662784656680232 6 TRUE TRUE TRUE TRUE TRUE TRUE 7.57061302644813 7.872760441121 7.06475541950623 6.97866621678449 7.94707260591948 8.70334762206245 7.94683544684597 7.52074524851424 7.33494210369046 7.04027546976759 7.79387050013256 9.10026343032389 -0.376222420397846 0.352015192606751 -0.270186684184237 -0.0616092529831 0.153202105786917 -0.396915808261433 7.75872423664705 7.69675284481762 7.19984876159834 7.00947084327604 7.87047155302602 8.90180552619317 -0.309721988321023 -0.0371378353464069 -0.426362916760679 -0.359007071374413 -0.361007905247641 -0.192055645848815 1661.95854503865 2576.51122243270 945.367708303187 897.095821795225 2360.35816962774 5471.5641169422 3300.06168929791 1880.53984497712 1897.17944976873 1366.18710744599 2905.53975111829 9860.49109595446 TRUE TRUE TRUE TRUE TRUE TRUE
5 0.206610009063814 6.30155521359233 0.123146381514318 0.196293341986066 6.40486021812423 6.19825020906042 1.17752605313747 1.05255739687024 1.22950298324976 0.369835815515775 0.566408213258403 8 0.60187138794606 4 FALSE FALSE TRUE TRUE TRUE TRUE 5.74379598217123 5.80147601391618 6.64471459302215 6.08011372023586 5.90387427055681 6.05502865078254 6.47149488093807 6.84367515116648 -0.160078288385575 -0.253552636866355 0.173219712084078 -0.763561430930618 5.82383512636402 5.92825233234936 6.55810473698011 6.46189443570117 -0.453896750809404 -0.31407486170651 -0.461974327032722 -0.0205341369337184 248.849328469716 282.71479078824 610.163790112016 432.614335844501 459.814269485605 498.730605701161 814.424757043505 947.609236632655 FALSE FALSE TRUE TRUE TRUE TRUE
6 0.213865327341419 6.40044190133479 0.172946254190075 0.18381185340901 6.5073745650055 6.29350923766408 1.25968055639857 1.16350128337771 1.23845585741933 0.297126365671632 0.485117851230951 16 0.514685117198532 6 FALSE TRUE TRUE TRUE TRUE TRUE 6.20564072512947 5.85468002296961 5.98436670197861 6.5803277614128 5.74407405180724 6.74062443565889 6.39160226414885 6.3201431968387 6.45604018535566 6.42269819187218 -0.53498371052942 -0.536922241179242 -0.335776494860092 0.124287576057139 -0.678624140064934 6.47313258039418 6.12314114355923 6.15225494940866 6.51818397338423 6.08338612183971 0.0540540807912364 -0.424520121980029 -0.321167020198462 -0.4668223620634 -0.0078056875507411 509.11186451866 282.144672371107 338.249298073963 570.730192448525 311.117672266233 823.52787236081 737.939855848224 652.444910276766 803.881094948964 618.069577237698 FALSE TRUE TRUE TRUE TRUE TRUE
7 0.117000347922064 6.16790373142756 0.0563773688038189 0.160246549529000 6.22640390538859 6.10940355746653 1.20700863451927 0.73012709643954 1.12411982079656 0.49807001965368 0.687025627866666 16 0.514685117198532 6 FALSE TRUE TRUE FALSE TRUE TRUE 6.05406945195357 5.62974235796595 6.63942266113576 6.33476707238563 6.03109462139683 5.75616758278429 6.23086619455574 6.75323759972068 0.0229748305567363 -0.126425224818338 0.40855646658002 -0.418470527335049 6.0425820366752 5.69295497037512 6.43514442784575 6.54400233605315 0.0788038795788517 -0.490494590353723 -0.475044941020253 -0.0222910287115910 442.956420555824 218 602.98974540796 557.588680045076 400.091264209633 404 644.44447400355 866.431553467389 FALSE TRUE TRUE FALSE TRUE TRUE
8 0.0251749753920625 7.87764177358291 0.0594749928496117 0.128096226006689 7.89022926127895 7.86505428588688 0.252858455376122 0.196531749426777 1.02549454113627 0.851932514384405 0.923101508468219 11 1 6 TRUE TRUE TRUE TRUE TRUE TRUE 7.31821358215787 7.79060022748903 7.30201070353955 7.30262236926194 8.03507856742354 8.26857967083084 7.43443908047693 8.01567014596883 7.61942788831743 7.6198632604905 8.29394645569364 8.41194738160865 -0.116225498319052 -0.225069918479797 -0.317417184777873 -0.317240891228561 -0.258867888270101 -0.143367710777809 7.3763263313174 7.90313518672893 7.46071929592849 7.46124281487622 8.16451251155859 8.34026352621975 -0.345566605824233 -0.0533002156803463 -0.435505668497953 -0.360759202824192 -0.314976516761044 -0.162516409156641 1268.29692966804 2354.18557743922 1193.03751709074 1239.22661674935 2637.50931371125 3595.07979585565 2012.67987340674 3109.82039844327 2533.05337736885 2441.19477884576 4681.78494206037 4881.48905335225 TRUE TRUE TRUE TRUE TRUE TRUE
9 -0.149108262502409 9.6484766089624 0.187630444454290 0.170654864900716 9.5739224777112 9.7230307402136 -0.843190453983837 -0.873741645684453 -1.16079865337361 0.422232523609097 0.618038659330819 6 0.662784656680232 6 TRUE TRUE TRUE TRUE TRUE TRUE 8.57449699179538 9.4136668745274 9.35439467610029 9.15016416448131 9.68538821777504 10.9377391848210 9.45668461019582 9.17820022743485 9.80227570963841 9.14087238735274 9.5086472844559 11.6633223308802 -0.882187618400434 0.235466647092561 -0.447881033538123 0.00929177712857132 0.176740933319122 -0.725583146059256 9.0155908009956 9.29593355098113 9.57833519286935 9.14551827591703 9.59701775111547 11.3005307578506 -0.159706239032436 -0.04614043029832 -0.462016186631689 -0.34959386852496 -0.129127377565247 -0.212413078328476 4888.51508267578 11975.2423417143 9167.19457001427 7905.92083257595 15075.4749814928 50591.1857610715 13856.8881829599 9909.71078344671 22771.9274230939 11110.7603831046 14374.4984301122 129253.241329977 TRUE TRUE TRUE TRUE TRUE TRUE
10 -0.0484508139619021 7.103588341006 0.0179476760132908 0.114806237520723 7.07936293402505 7.12781374798696 -0.885875298486113 -0.422022487699386 -1.0496437427335 0.690539917160242 0.828541346359721 8 0.850671852899576 6 TRUE TRUE TRUE TRUE TRUE TRUE 6.61066330625313 7.13455625606436 6.46879464661996 6.93409486890224 7.22879665821278 7.56037542373494 6.85042727551064 7.27454576439637 6.79404030864919 6.81589604818193 7.21917408902994 7.6072194796991 -0.239763969257508 -0.139989508332012 -0.325245662029231 0.118198820720312 0.00962256918284338 -0.0468440559641592 6.73054529088189 7.20455101023036 6.63141747763457 6.87499545854208 7.22398537362136 7.58379745171702 -0.396975899891249 -0.0135499469934069 -0.422407056857498 -0.356582225162467 -0.422665212545984 -0.122051309590930 609.217505788053 1246.10913347150 521.960084347262 859.029923216443 1115.95302743093 1806.86715125717 1151.60882902658 1452.90566605339 1102.39882794939 1090.27709745416 1686.66198058951 2139.32392348112 TRUE TRUE TRUE TRUE TRUE TRUE
11 0.167096086880166 5.80857420998326 5.89212225342334 5.72502616654318 1.18186782184440 1 1 1 FC is not reliable t and regul. t values unreliable FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE
12 -0.0242243040009700 7.12476991323164 0.104605627863052 0.145343422167629 7.11265776123115 7.13688206523212 -0.183463387410075 -0.166669420877069 -1.02452009607620 0.874160699804834 0.936392421407969 9 0.979123831000863 6 TRUE TRUE TRUE TRUE TRUE TRUE 6.50209954306463 7.09637212810428 6.53129927067247 6.5946870251627 7.23517745414132 7.50794837745492 6.77120640952374 7.36979660957303 7.044418237056 6.99284655061349 7.42707148803848 7.43769261971675 -0.269106866459107 -0.273424481468755 -0.51311896638353 -0.398159525450792 -0.191894033897157 0.0702557577381692 6.63665297629418 7.23308436883865 6.78785875386423 6.79376678788809 7.3311244710899 7.47282049858584 -0.402017012702532 -0.0148063451836615 -0.424994711940592 -0.353898945369173 -0.420093798934929 -0.114299372707389 545.166382309462 1198.67127985095 554.907767195149 612.615534556424 1124.54136355290 1721.23733346831 1066.58252679101 1599.10564835014 1417.87647763507 1299.57949182808 2073.7594272916 1798.74109237619 TRUE TRUE TRUE TRUE TRUE TRUE
13 -0.0469088175162494 10.3342544350898 0.213777307683436 0.179479921245432 10.3108000263317 10.3577088438479 -0.248513112608018 -0.261359695227989 -1.04802644306863 0.80423936774229 0.896028003604626 9 0.979123831000863 6 TRUE TRUE TRUE TRUE TRUE TRUE 9.79823870412372 10.7347229933667 10.4724784274699 9.84340631242075 8.94363269243556 11.0389254796862 10.2015342750857 10.9048781486293 10.0856886962179 9.94804676345328 10.1749710754186 10.6912397932917 -0.403295570961998 -0.170155155262561 0.386789731251908 -0.104640451032529 -1.23133838298301 0.347685686394477 9.99988648960472 10.8198005709980 10.2790835618439 9.89572653793702 9.55930188392706 10.8650826364890 -0.127499607007805 -0.0410822420334085 -0.47175088863126 -0.356327809776946 -0.128683498544831 -0.216869109299487 16890.2008371096 44989.3859138504 27906.1670095957 15760.1898164808 7181.6966988889 55853.6929541985 28718.1348524430 55571.1393840619 30380.7401989974 24989.491321551 27981.8908535608 49004.840010609 TRUE TRUE TRUE TRUE TRUE TRUE
14 -0.149233735862068 8.14670155543722 0.0264390642367349 0.116375356069194 8.07208468750618 8.22131842336825 -2.24812055397745 -1.28234826429521 -1.16094431181847 0.25595324990883 0.434857065488919 3 0.295062061521857 6 TRUE TRUE TRUE TRUE TRUE TRUE 7.39194382829686 8.29737880010225 7.4241538073438 7.40193673207796 8.45012891786909 8.9438978087217 7.69679787796631 8.11717268985403 7.50638645985961 7.54121260376934 8.60660896791818 8.53938752115185 -0.304854049669448 0.180206110248223 -0.082232652515805 -0.139275871691379 -0.156480050049098 0.404510287569853 7.54437085313158 8.20727574497814 7.4652701336017 7.47157466792365 8.52836894289364 8.74164266493677 -0.330897558603184 -0.0692580921389108 -0.435607447360446 -0.361205183216268 -0.248615180426053 -0.183689452418995 1375.39335973548 3876.73953778445 1347.96332437284 1368.3133657347 4129.12718246692 6988.72267523843 2597.34917870882 3469.62478483724 2262.41970069751 2257.05285630869 6191.40028964291 5603.97948886206 TRUE TRUE TRUE TRUE TRUE TRUE
15 -0.0262368401386992 7.17039051985446 0.00949058983783744 0.110269903110036 7.15727209978511 7.18350893992381 -0.659690989221284 -0.237932920939616 -1.02658405599370 0.821376025410417 0.90553213236173 6 0.662784656680232 6 FALSE TRUE TRUE TRUE TRUE TRUE 7.01114551842994 6.61611072525302 6.36025908960577 7.09535945419009 8.5337978004649 7.12598404664608 6.68705673176899 6.35712979807395 6.80198179808505 8.42566548292077 -0.114838528216145 -0.0709460065159702 0.00312929153181851 0.293377656105044 0.108132317544133 7.06856478253801 6.651583728511 6.35869444383986 6.94867062613757 8.47973164169284 -0.00436154415525588 -0.422691276624282 -0.340743080933147 -0.444534798254559 -0.169267389477929 1106.50839489377 604.719725431153 487.791250584194 965.930663829862 4671.16650180798 1246.58715304161 990.690693509108 683.687771191887 1123.55067726984 4965.64847720601 FALSE TRUE TRUE TRUE TRUE TRUE
16 -0.126230069279305 8.63728275337303 0.0137413240179053 0.111454347688056 8.57416771873338 8.70039778801268 -2.63769244613396 -1.13257196240208 -1.13454316178615 0.308765450626393 0.498722334209691 1 0.131683526011561 6 TRUE TRUE TRUE TRUE TRUE TRUE 7.8594298163505 8.60299269675657 8.05402960120632 8.07708841464921 8.80772769364206 9.3422531744819 8.1072540233709 8.64004551081946 8.3470657035321 8.2246765145186 9.11906272861323 9.2000597245075 -0.247824207020399 -0.0370528140628898 -0.293036102325774 -0.147588099869395 -0.311335034971165 0.142193449974406 7.9833419198607 8.62151910378801 8.2005476523692 8.15088246458391 8.96339521112765 9.2711564494947 -0.281208006570977 -0.0565499120186648 -0.445138675442398 -0.37184544500969 -0.182446800052059 -0.207066157359994 2250.31573735102 5296.05636631851 2518.60451563567 2673.55865123288 6102.8081312357 10287.8626491674 3819.43592336408 5815.72344190692 5269.20639627322 4494.45294737074 9999.45758134219 10977.3880383219 TRUE TRUE TRUE TRUE TRUE TRUE
17 -0.0387559269467397 6.5887621516916 0.0549549361843852 0.143731307103403 6.56938418821823 6.60814011516497 -0.404958388761562 -0.269641511844443 -1.03951673466143 0.798210326811482 0.892630703628092 9 0.979123831000863 6 FALSE FALSE TRUE TRUE TRUE TRUE 6.46807839887714 6.19667146405224 6.24868316903748 7.79137377495769 6.42238262005948 6.1462667506816 6.86682072339915 7.84362139426933 0.0456957788176627 0.05040471337063 -0.618137554361662 -0.052247619311643 6.44523050946831 6.17146910736692 6.55775194621831 7.81749758461351 -0.417827997041519 -0.322577656632945 -0.462024866920478 -0.141233538755264 522.781921159979 417.958704982142 410.621035984327 2254.66572924342 758.464973120748 548.702049361645 1209.34377511610 2735.96138137133 FALSE FALSE TRUE TRUE TRUE TRUE
18 -0.107641871415536 7.37765165858442 0.0137089892126521 0.110081290215323 7.32383072287665 7.43147259429219 -2.25192616745649 -0.97783984185673 -1.11364884447756 0.373061882159961 0.56975302813117 3 0.295062061521857 6 TRUE TRUE TRUE TRUE TRUE TRUE 6.97537828759086 7.41517936744434 6.88464101548253 6.85102618053909 7.21594064775309 8.49491591952076 7.0836734103818 7.55967493201689 6.96151962490977 6.71659688578325 7.46570342094698 8.26620724746907 -0.108295122790938 -0.144495564572551 -0.0768786094272427 0.134429294755839 -0.24976277319389 0.228708672051689 7.02952584898632 7.48742714973061 6.92308032019615 6.78381153316117 7.34082203435004 8.38056158349491 -0.376642622015476 -0.0255930145949712 -0.42224683223212 -0.353582697491023 -0.420000849783939 -0.164363664997504 886.301314240972 1639.88740036454 791.173747674206 791.741406688902 1103.16679018852 4504.05817945571 1439.41883080858 1943.93867611477 1303.28468955905 985.735669044958 2155.34017916067 4223.37174607929 TRUE TRUE TRUE TRUE TRUE TRUE
19 -0.237618860761184 5.7174629765876 0.0370667472715424 0.235698895891800 5.598653546207 5.83627240696819 -1.74543495341429 -1.00814583734947 -1.26822573010804 0.497417631438922 0.686504605163317 0 0.70834008097166 2 FC is not reliable t and regul. t values unreliable FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE
20 0.136460403001610 8.11119806582079 0.133087690270925 0.152978315495171 8.17942826732159 8.04296786431998 0.916248614073535 0.892024484384637 1.14620949042183 0.413244770603919 0.609263546514382 16 0.514685117198532 6 TRUE TRUE TRUE TRUE TRUE TRUE 7.83385203392517 8.56322105835562 7.75834797107225 7.0617523032748 7.5682264870975 9.4306331111523 7.2354301602429 8.52898921704718 7.52674709625598 7.43366472346395 8.11933844035619 9.13982167909282 0.598421873682266 0.0342318413084417 0.231600874816272 -0.371912420189159 -0.551111953258687 0.290811432059478 7.53464109708403 8.5461051377014 7.64254753366411 7.24770851336937 7.84378246372684 9.28522739512256 -0.331828450901704 -0.0631526605599859 -0.440570252710171 -0.358162736734817 -0.366391596510751 -0.207601674191915 2138.66655459214 5072.78232482206 1878.18815675922 975.22765388525 1611.67725474359 11235.4841202539 1638.18530313852 5221.63341837915 2314.69271824537 2023.82809162312 4034.08277892225 10338.4219068633 TRUE TRUE TRUE TRUE TRUE TRUE

Total number of rows: 34992

Table truncated, full table size 18351 Kbytes.




Supplementary data files not provided
Processed data included within Sample table
| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap