|
| Status |
Public on Nov 18, 2020 |
| Title |
Genomic DNA from blood 196 |
| Sample type |
genomic |
| |
|
| Source name |
whole blood
|
| Organism |
Homo sapiens |
| Characteristics |
tissue: whole blood
Sex: Female
age: 67
disease state: mild cognitive impairment
disease state2: mild cognitive impairment to alzheimer's disease converter
age<65.exclusion: Included
|
| Extracted molecule |
genomic DNA |
| Extraction protocol |
Genomic DNA was extracted and purified from whole blood samples using Qiagen DNeasy Kit according to standard instructions
|
| Label |
Cy3,Cy5
|
| Label protocol |
Standard Illumina Protocol
|
| |
|
| Hybridization protocol |
DNA was sodium-bisulfite treated using a Zymo EZ-96 DNA methylation kit, and was subsequently amplified, fragmented and hybridised to Illumina Infinium HumanMethylation 450 Beadchip using standard Illumina protocol
|
| Scan protocol |
Arrays were imaged using standard recommended Illumina scanner settings
|
| Description |
mild cognitive impairment sample
|
| Data processing |
R 3.5.2
|
| |
|
| Submission date |
Feb 06, 2020 |
| Last update date |
Nov 18, 2020 |
| Contact name |
Katie Lunnon |
| Organization name |
University of Exeter
|
| Lab |
Dementia Genomics
|
| Street address |
RILD South, Barrack Road
|
| City |
Exeter |
| State/province |
Devon |
| ZIP/Postal code |
EX2 5DW |
| Country |
United Kingdom |
| |
|
| Platform ID |
GPL13534 |
| Series (1) |
| GSE144858 |
An epigenome-wide association study of Alzheimer’s disease blood highlights robust DNA hypermethylation in the HOXB6 gene. |
|
