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    Ugt2b35 UDP glucuronosyltransferase 2 family, polypeptide B35 [ Mus musculus (house mouse) ]

    Gene ID: 243085, updated on 2-May-2024

    Summary

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    Official Symbol
    Ugt2b35provided by MGI
    Official Full Name
    UDP glucuronosyltransferase 2 family, polypeptide B35provided by MGI
    Primary source
    MGI:MGI:3576100
    See related
    Ensembl:ENSMUSG00000035811 AllianceGenome:MGI:3576100
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C730031G17
    Summary
    Predicted to enable glucuronosyltransferase activity. Predicted to be involved in aromatic compound catabolic process. Predicted to be active in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in osteoporosis. Orthologous to human UGT2B15 (UDP glucuronosyltransferase family 2 member B15) and UGT2B17 (UDP glucuronosyltransferase family 2 member B17). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in liver adult (RPKM 9.8), liver E18 (RPKM 5.1) and 6 other tissues See more
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    Genomic context

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    See Ugt2b35 in Genome Data Viewer
    Location:
    5 E1; 5 43.56 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (87148719..87161133)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (87000860..87013274)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene UDP glucuronosyltransferase 2 family, polypeptide B1 pseudogene Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene Neighboring gene Rho GTPase activating protein 11A pseudogene Neighboring gene STARR-seq mESC enhancer starr_13556 Neighboring gene UDP glucuronosyltransferase 2 family, polypeptide B36

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. The miR-379/miR-410 cluster at the imprinted Dlk1-Dio3 domain controls neonatal metabolic adaptation. Labialle S, et al. EMBO J, 2014 Oct 1. PMID 25124681, Free PMC Article
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables glucuronosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glucuronosyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in androgen metabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in catabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cellular glucuronidation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cellular glucuronidation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in estrogen metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in estrogen metabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    UDP glucuronosyltransferase 2 family, polypeptide B35
    NP_766469.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172881.3 → NP_766469.1  UDP glucuronosyltransferase 2 family, polypeptide B35 precursor

      See identical proteins and their annotated locations for NP_766469.1

      Status: VALIDATED

      Source sequence(s)
      AC119816, AK083294
      Consensus CDS
      CCDS39128.1
      UniProtKB/TrEMBL
      Q3UEI8, Q8BJL9
      Related
      ENSMUSP00000031186.8, ENSMUST00000031186.9
      Conserved Domains (2) summary
      PHA03392
      Location:8 → 506
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      pfam00201
      Location:24 → 525
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      87148719..87161133
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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