vaspb vasodilator stimulated phosphoprotein b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: vaspbprovided by ZNC
Official Full Name: vasodilator stimulated phosphoprotein bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-7118
See related: Ensembl:ENSDARG00000017105 AllianceGenome:ZFIN:ZDB-GENE-030131-7118
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: vasp; wu:fb23b04; wu:fk84g05; zgc:110347; si:dkey-113g17.1; si:ch211-202c21.1
Summary: Predicted to enable SH3 domain binding activity and profilin binding activity. Predicted to be involved in actin cytoskeleton organization; nervous system development; and positive regulation of actin filament polymerization. Predicted to act upstream of or within actin polymerization or depolymerization. Predicted to be located in cell projection; cytoplasm; and cytoskeleton. Is expressed in several structures, including apical ectodermal ridge pectoral fin bud; epidermis; pectoral fin; pharyngeal arch; and solid lens vesicle. Orthologous to human VASP (vasodilator stimulated phosphoprotein). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 18

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (40761913..40856360, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (40771721..40866180, complement)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

fb94d11.x1 (e-PCR)
- UniSTS:187665

fb23b04 (e-PCR)
- UniSTS:188974

fe47f03.x1 (e-PCR)
- UniSTS:196489

fk66f05.x1 (e-PCR)
- UniSTS:201397

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables SH3 domain binding	IBA Inferred from Biological aspect of Ancestor more info
enables SH3 domain binding	IEA Inferred from Electronic Annotation more info
enables actin binding	IEA Inferred from Electronic Annotation more info
enables profilin binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in actin cytoskeleton organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in axon guidance	IBA Inferred from Biological aspect of Ancestor more info
involved_in neural tube closure	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of actin filament polymerization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: protein enabled homolog; vasodilator stimulated phosphoprotein b; vasodilator-stimulated phosphoprotein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007129.7 Reference GRCz11 Primary Assembly

Range

40761913..40856360 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005173680.4 → XP_005173737.1 vasodilator-stimulated phosphoprotein isoform X2

UniProtKB/TrEMBL

A0A8M2BKY8

Conserved Domains (2) summary

cd01207
Location:5 → 114

EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain

pfam08776
Location:392 → 422

VASP_tetra; VASP tetramerization domain
XM_005173679.4 → XP_005173736.1 vasodilator-stimulated phosphoprotein isoform X1

UniProtKB/TrEMBL

A0A8M2BKY2, Q1LVK6

Related

ENSDARP00000089635.3, ENSDART00000098865.5

Conserved Domains (2) summary

cd01207
Location:5 → 114

EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain

pfam08776
Location:411 → 441

VASP_tetra; VASP tetramerization domain

Reference GRCz11 ALT_DRER_TU_1

Genomic

NW_018395045.1 Reference GRCz11 ALT_DRER_TU_1

Range

3633..78922 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021473340.1 → XP_021329015.1 protein enabled homolog isoform X3

UniProtKB/TrEMBL

A0A8M9Q724

Conserved Domains (1) summary

cd01207
Location:5 → 114

EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001017790.2: Suppressed sequence

Description

NM_001017790.2: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.