rnf19a ring finger protein 19A, RBR E3 ubiquitin protein ligase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rnf19aprovided by ZNC
Official Full Name: ring finger protein 19A, RBR E3 ubiquitin protein ligaseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-9414
See related: Ensembl:ENSDARG00000012040 AllianceGenome:ZFIN:ZDB-GENE-030131-9414
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fj68f04; wu:fj68f04
Summary: Predicted to enable metal ion binding activity and ubiquitin-protein transferase activity. Predicted to act upstream of or within protein ubiquitination. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human RNF19A (ring finger protein 19A, RBR E3 ubiquitin protein ligase). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 19

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (12030832..12078583, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (12111304..12159055, complement)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info
enables ubiquitin-protein transferase activity	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within protein ubiquitination	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: E3 ubiquitin-protein ligase RNF19A

Names: ring finger protein 19A, E3 ubiquitin protein ligase

NP_001313624.1

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001326695.1 → NP_001313624.1 E3 ubiquitin-protein ligase RNF19A

Status: VALIDATED

Source sequence(s)

FP236813

UniProtKB/TrEMBL

A0A8M1P8W1, E7F0K2

Related

ENSDARP00000006534.6, ENSDART00000024193.8

Conserved Domains (3) summary

smart00647
Location:266 → 331

IBR; In Between Ring fingers

pfam01485
Location:364 → 402

IBR; IBR domain, a half RING-finger domain

cl00570
Location:428 → 517

AzlC; AzlC protein