slc37a4a solute carrier family 37 member 4a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: slc37a4aprovided by ZNC
Official Full Name: solute carrier family 37 member 4aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2230
See related: Ensembl:ENSDARG00000038106 AllianceGenome:ZFIN:ZDB-GENE-040426-2230
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fc25d06; slc37a4; zgc:77098; wu:fc25d06
Summary: Predicted to enable glucose 6-phosphate:inorganic phosphate antiporter activity. Acts upstream of or within response to steroid hormone. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of endoplasmic reticulum membrane. Is expressed in intestinal bulb; liver; ovary; and yolk syncytial layer. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II. Orthologous to human SLC37A4 (solute carrier family 37 member 4). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 15

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	15	NC_007126.7 (9294596..9315555)
105	previous assembly	GRCz10 (GCF_000002035.5)	15	NC_007126.6 (9318536..9339014)

Chromosome 15 - NC_007126.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables glucose 6-phosphate:phosphate antiporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in glucose-6-phosphate transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in phosphate ion transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within response to steroid hormone	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: glucose-6-phosphate exchanger SLC37A4a; glucose-6-phosphate translocase

Names: glycerol-6-phosphate transporter; solute carrier family 37 (glucose-6-phosphate transporter), member 4; solute carrier family 37 (glucose-6-phosphate transporter), member 4a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_214738.1 → NP_999903.1 glucose-6-phosphate exchanger SLC37A4a

See identical proteins and their annotated locations for NP_999903.1

Status: PROVISIONAL

Source sequence(s)

BC066719

UniProtKB/TrEMBL

Q6NY67

Related

ENSDARP00000055553.5, ENSDART00000055554.6

Conserved Domains (2) summary

cd06174
Location:14 → 415

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

TIGR00881
Location:18 → 397

2A0104; phosphoglycerate transporter family protein

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007126.7 Reference GRCz11 Primary Assembly

Range

9294596..9315555

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021481373.1 → XP_021337048.1 glucose-6-phosphate translocase isoform X1

UniProtKB/TrEMBL

A0A8M3AH42, F1R0A9

Conserved Domains (1) summary

cl27298
Location:18 → 397

UhpC; Sugar phosphate permease [Carbohydrate transport and metabolism]
XM_009291487.3 → XP_009289762.1 glucose-6-phosphate translocase isoform X1

See identical proteins and their annotated locations for XP_009289762.1

UniProtKB/TrEMBL

A0A8M3AH42, F1R0A9

Conserved Domains (1) summary

cl27298
Location:18 → 397

UhpC; Sugar phosphate permease [Carbohydrate transport and metabolism]