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    tpd52l2a tpd52 like 2a [ Danio rerio (zebrafish) ]

    Gene ID: 335107, updated on 27-Mar-2024

    Summary

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    Official Symbol
    tpd52l2aprovided by ZNC
    Official Full Name
    tpd52 like 2aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-7047
    See related
    Ensembl:ENSDARG00000027154 AllianceGenome:ZFIN:ZDB-GENE-030131-7047
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fk69c03; zgc:55624; zgc:77795; wu:fc29c04; wu:fk69c03
    Summary
    Predicted to be active in cytoplasm. Orthologous to several human genes including TPD52L2 (TPD52 like 2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See tpd52l2a in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (23194223..23211642)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (23172984..23190403)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 5aa Neighboring gene si:ch211-196c10.15 Neighboring gene pancreatic progenitor cell differentiation and proliferation factor a Neighboring gene PTK6 protein tyrosine kinase 6a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RNA-Seq analysis in mutant zebrafish reveals role of U1C protein in alternative splicing regulation. Rösel TD, et al. EMBO J, 2011 May 18. PMID 21468032, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    tpd52 like 2a; tumor protein D52-like 2a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001328541.1 → NP_001315470.1  tpd52 like 2a isoform 2

      Status: VALIDATED

      Source sequence(s)
      CR759927, EH435837, EH612774
      UniProtKB/TrEMBL
      A0A8M1P523, E9QF87
      Related
      ENSDARP00000119359.1, ENSDART00000144855.2
      Conserved Domains (1) summary
      pfam04201
      Location:36 → 198
      TPD52; Tumour protein D52 family

    2. NM_001328542.1 → NP_001315471.1  tpd52 like 2a isoform 3

      Status: VALIDATED

      Source sequence(s)
      CR759927, EH435837, EH450192, EH612774
      UniProtKB/TrEMBL
      A0A8M1PA60, E9QG97
      Related
      ENSDARP00000120448.1, ENSDART00000137815.3
      Conserved Domains (1) summary
      pfam04201
      Location:36 → 195
      TPD52; Tumour protein D52 family

    3. NM_001328543.1 → NP_001315472.1  tpd52 like 2a isoform 4

      Status: VALIDATED

      Source sequence(s)
      CR759927, EH435837, EH612774
      UniProtKB/TrEMBL
      A0A2R8QN88, A0A8M1P413
      Related
      ENSDARP00000157009.1, ENSDART00000186842.1

    4. NM_212733.2 → NP_997898.1  tpd52 like 2a isoform 1

      See identical proteins and their annotated locations for NP_997898.1

      Status: VALIDATED

      Source sequence(s)
      CR759927, EH435837, EH612774
      UniProtKB/TrEMBL
      Q6NX04, Q803K5
      Related
      ENSDARP00000038087.6, ENSDART00000028946.8
      Conserved Domains (1) summary
      pfam04201
      Location:36 → 175
      TPD52; Tumour protein D52 family

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      23194223..23211642
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005167010.4 → XP_005167067.1  tumor protein D52-like 2a isoform X1

      UniProtKB/TrEMBL
      A0A8M2BEH5
      Related
      ENSDARP00000115292.1, ENSDART00000136914.3
      Conserved Domains (1) summary
      pfam04201
      Location:36 → 218
      TPD52; Tumour protein D52 family

    2. XM_009303929.3 → XP_009302204.1  tumor protein D52-like 2a isoform X3

      UniProtKB/TrEMBL
      A0A8M3B1Z0
      Conserved Domains (1) summary
      pfam04201
      Location:36 → 203
      TPD52; Tumour protein D52 family

    3. XM_021478189.1 → XP_021333864.1  tumor protein D52-like 2a isoform X2

      UniProtKB/TrEMBL
      A0A8M9Q9I8
      Conserved Domains (1) summary
      pfam04201
      Location:36 → 210
      TPD52; tumor protein D52 family
    Nucleotide Protein Strain
    Heading Accession and Version

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