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    Wdr90 WD repeat domain 90 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 102555298, updated on 10-Mar-2024

    Summary

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    Official Symbol
    Wdr90provided by RGD
    Official Full Name
    WD repeat domain 90provided by RGD
    Primary source
    RGD:7520481
    See related
    Ensembl:ENSRNOG00000020006 AllianceGenome:RGD:7520481
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1561785
    Summary
    Predicted to be involved in cilium assembly. Predicted to be active in centriole. Orthologous to human WDR90 (WD repeat domain 90). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Adrenal (RPKM 47.6), Thymus (RPKM 38.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Wdr90 in Genome Data Viewer
    Location:
    10q12
    Exon count:
    41
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (15369184..15385797, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (14864672..14881285, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (15211660..15229477, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene jumonji domain containing 8 Neighboring gene STIP1 homology and U-box containing protein 1 Neighboring gene rhomboid like 1 Neighboring gene ras homolog family member T2 Neighboring gene MAPK regulated co-repressor interacting protein 2 Neighboring gene methyltransferase like 26 Neighboring gene transfer RNA glycine (anticodon CCC) 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Identification of Chlamydomonas Central Core Centriolar Proteins Reveals a Role for Human WDR90 in Ciliogenesis. Hamel V, et al. Curr Biol, 2017 Aug 21. PMID 28781053, Free PMC Article
    2. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cilium assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in centriole ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    WD repeat-containing protein 90
    Names
    WD repeat-containing protein 90-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      15369184..15385797 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006246068.4 → XP_006246130.1  WD repeat-containing protein 90 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZMK6, D3ZMM2
      Related
      ENSRNOP00000027121.7, ENSRNOT00000027121.7
      Conserved Domains (4) summary
      COG2319
      Location:1256 → 1679
      WD40; WD40 repeat [General function prediction only]
      pfam05018
      Location:60 → 236
      DUF667; Protein of unknown function (DUF667)
      sd00039
      Location:1285 → 1327
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:758 → 1058
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. XM_006246066.4 → XP_006246128.1  WD repeat-containing protein 90 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZMK6
      Related
      ENSRNOP00000079372.1, ENSRNOT00000113344.1
      Conserved Domains (4) summary
      COG2319
      Location:1256 → 1679
      WD40; WD40 repeat [General function prediction only]
      pfam05018
      Location:60 → 236
      DUF667; Protein of unknown function (DUF667)
      sd00039
      Location:1285 → 1327
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:758 → 1058
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    3. XM_039087116.1 → XP_038943044.1  WD repeat-containing protein 90 isoform X3

      Conserved Domains (3) summary
      COG2319
      Location:732 → 1155
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:761 → 803
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:234 → 534
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    4. XM_063270092.1 → XP_063126162.1  WD repeat-containing protein 90 isoform X4

    Nucleotide Protein Strain
    Heading Accession and Version

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