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    ACTG2 actin gamma 2, smooth muscle [ Canis lupus familiaris (dog) ]

    Gene ID: 475792, updated on 5-Mar-2024

    Summary

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    Official Symbol
    ACTG2provided by VGNC
    Official Full Name
    actin gamma 2, smooth muscleprovided by VGNC
    Primary source
    VGNC:VGNC:37541
    See related
    Ensembl:ENSCAFG00845022216
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See ACTG2 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 17 NC_051821.1 (50003715..50028411, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 17 NC_006599.4 (48784850..48810117, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 17 NC_049238.1 (49645142..49670439, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 17 NC_049277.1 (49019875..49044569, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 17 NC_049758.1 (49087331..49111998, complement)

    Chromosome 17 - NC_051821.1Genomic Context describing neighboring genes Neighboring gene tet methylcytosine dioxygenase 3 Neighboring gene uncharacterized LOC111090655 Neighboring gene deoxyguanosine kinase Neighboring gene uncharacterized LOC111090657 Neighboring gene STAM binding protein Neighboring gene uncharacterized LOC111090659 Neighboring gene chromosome 17 C2orf78 homolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Tenascin-C in chronic canine hepatitis: immunohistochemical localization and correlation with necro-inflammatory activity, fibrotic stage, and expression of alpha-smooth muscle actin, cytokeratin 7, and CD3+ cells. Mekonnen GA, et al. Vet Pathol, 2007 Nov. PMID 18039893
    2. Immunohistochemical analysis of collagen types I, III, IV and alpha-actin in the urethra of sexually intact and ovariectomized beagles. Augsburger HR, et al. Int Urogynecol J Pelvic Floor Dysfunct, 2007 Sep. PMID 17206491

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. This study reported the correlation of tenascin-C with the inflammatory activity and expression of alpha-smooth muscle actin (alpha-SMA), cytokeratin 7 (CK7), and CD3+ T-lymphocytes in canine chronic hepatitis.
      Title: Tenascin-C in chronic canine hepatitis: immunohistochemical localization and correlation with necro-inflammatory activity, fibrotic stage, and expression of alpha-smooth muscle actin, cytokeratin 7, and CD3+ cells.
    2. Ovariectomy does not appear to have an effect on smooth muscle actin in the dog
      Title: Immunohistochemical analysis of collagen types I, III, IV and alpha-actin in the urethra of sexually intact and ovariectomized beagles.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in vascular associated smooth muscle contraction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    actin, gamma-enteric smooth muscle
    Names
    actin, gamma 2, smooth muscle, enteric
    smooth muscle enteric actin gamma 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051821.1 Reference ROS_Cfam_1.0

      Range
      50003715..50028411 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038691713.1 → XP_038547641.1  actin, gamma-enteric smooth muscle

      UniProtKB/TrEMBL
      A0A8C0K5X1, A0A8C0P2V8, A0A8C0R0H4, A0A8I3PAR6
      Related
      ENSCAFP00845030706.1, ENSCAFT00845039204.1
      Conserved Domains (1) summary
      PTZ00281
      Location:1 → 376
      PTZ00281; actin; Provisional

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049277.1 Alternate UMICH_Zoey_3.1

      Range
      49019875..49044569 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038499154.1 → XP_038355082.1  actin, gamma-enteric smooth muscle

      Conserved Domains (1) summary
      PTZ00281
      Location:1 → 376
      PTZ00281; actin; Provisional

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049758.1 Alternate UNSW_CanFamBas_1.0

      Range
      49087331..49111998 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038625784.1 → XP_038481712.1  actin, gamma-enteric smooth muscle

      Conserved Domains (1) summary
      PTZ00281
      Location:1 → 376
      PTZ00281; actin; Provisional

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049238.1 Alternate UU_Cfam_GSD_1.0

      Range
      49645142..49670439 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038561741.1 → XP_038417669.1  actin, gamma-enteric smooth muscle

      UniProtKB/TrEMBL
      A0A8C0K5X1, A0A8C0P2V8, A0A8C0R0H4, A0A8I3PAR6
      Conserved Domains (1) summary
      PTZ00281
      Location:1 → 376
      PTZ00281; actin; Provisional

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006599.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      48784850..48810117 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_533002.6 → XP_533002.2  actin, gamma-enteric smooth muscle

      See identical proteins and their annotated locations for XP_533002.2

      UniProtKB/TrEMBL
      A0A8C0K5X1, A0A8C0P2V8, A0A8C0R0H4, A0A8I3PAR6
      Conserved Domains (1) summary
      PTZ00281
      Location:1 → 376
      PTZ00281; actin; Provisional
    Nucleotide Protein
    Heading Accession and Version

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