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    DSTN destrin, actin depolymerizing factor [ Canis lupus familiaris (dog) ]

    Gene ID: 477147, updated on 5-Mar-2024

    Summary

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    Official Symbol
    DSTNprovided by VGNC
    Official Full Name
    destrin, actin depolymerizing factorprovided by VGNC
    Primary source
    VGNC:VGNC:40111
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See DSTN in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 24 NC_051828.1 (5803229..5840053, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 24 NC_006606.4 (5327813..5364670, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 24 NC_049245.1 (5786183..5822988, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 24 NC_049284.1 (5416513..5453319, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 24 NC_049765.1 (5510480..5547273, complement)

    Chromosome 24 - NC_051828.1Genomic Context describing neighboring genes Neighboring gene BANF family member 2 Neighboring gene ribosome binding protein 1 Neighboring gene 60S ribosomal protein L39-like Neighboring gene beaded filament structural protein 1 Neighboring gene proprotein convertase subtilisin/kexin type 2 Neighboring gene uncharacterized LOC111092048

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament fragmentation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actin filament severing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell motility IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin cortical patch IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    destrin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051828.1 Reference ROS_Cfam_1.0

      Range
      5803229..5840053 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038433072.1 → XP_038289000.1  destrin

      UniProtKB/TrEMBL
      A0A8C0PHL7
      Conserved Domains (1) summary
      cd11286
      Location:3 → 152
      ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049284.1 Alternate UMICH_Zoey_3.1

      Range
      5416513..5453319 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038508284.1 → XP_038364212.1  destrin

      Conserved Domains (1) summary
      cd11286
      Location:3 → 152
      ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049765.1 Alternate UNSW_CanFamBas_1.0

      Range
      5510480..5547273 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038635782.1 → XP_038491710.1  destrin

      Conserved Domains (1) summary
      cd11286
      Location:3 → 152
      ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049245.1 Alternate UU_Cfam_GSD_1.0

      Range
      5786183..5822988 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038571540.1 → XP_038427468.1  destrin

      UniProtKB/TrEMBL
      A0A8C0PHL7
      Conserved Domains (1) summary
      cd11286
      Location:3 → 152
      ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006606.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      5327813..5364670 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038457503.1 → XP_038313431.1  destrin

      UniProtKB/TrEMBL
      A0A8C0PHL7
      Conserved Domains (1) summary
      cd11286
      Location:3 → 152
      ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors
    Nucleotide Protein
    Heading Accession and Version

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