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    Wdr95 WD40 repeat domain 95 [ Mus musculus (house mouse) ]

    Gene ID: 381693, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Wdr95provided by MGI
    Official Full Name
    WD40 repeat domain 95provided by MGI
    Primary source
    MGI:MGI:1923042
    See related
    Ensembl:ENSMUSG00000029658 AllianceGenome:MGI:1923042
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4930434E21Rik
    Summary
    Orthologous to human WDR49 (WD repeat domain 49). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Wdr95 in Genome Data Viewer
    Location:
    5 G3; 5 89.18 cM
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (149407874..149535359)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (149484409..149611894)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:150230952-150231169 Neighboring gene mesenteric estrogen dependent adipogenesis Neighboring gene RIKEN cDNA 4933425D22 gene Neighboring gene testis expressed 26 Neighboring gene STARR-seq mESC enhancer starr_14933 Neighboring gene predicted gene 15997 Neighboring gene predicted gene, 54316 Neighboring gene STARR-seq mESC enhancer starr_14938 Neighboring gene predicted gene, 35763 Neighboring gene STARR-positive B cell enhancer ABC_E3638 Neighboring gene STARR-positive B cell enhancer ABC_E1317 Neighboring gene heat shock 105kDa/110kDa protein 1 Neighboring gene STARR-seq mESC enhancer starr_14940 Neighboring gene predicted gene, 20005 Neighboring gene NME/NM23 nucleoside diphosphate kinase, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC381693

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029440.3 → NP_083716.2  uncharacterized protein LOC381693

      Status: VALIDATED

      Source sequence(s)
      AK087389, AW122438
      Consensus CDS
      CCDS39409.1
      UniProtKB/TrEMBL
      E9PUB4, Q8BN84
      Related
      ENSMUSP00000106128.2, ENSMUST00000110502.7
      Conserved Domains (4) summary
      COG2319
      Location:12 → 460
      WD40; WD40 repeat [General function prediction only]
      pfam00400
      Location:425 → 460
      WD40; WD domain, G-beta repeat
      sd00039
      Location:47 → 87
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:12 → 301
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      149407874..149535359
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017320945.2 → XP_017176434.1  uncharacterized protein LOC381693 isoform X1

      Conserved Domains (4) summary
      COG2319
      Location:799 → 939
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:450 → 758
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:462 → 498
      7WD40; WD40 repeat [structural motif]
      pfam13833
      Location:125 → 178
      EF-hand_8; EF-hand domain pair
    Nucleotide Protein Strain
    Heading Accession and Version

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