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    ppp4r1 protein phosphatase 4, regulatory subunit 1 [ Danio rerio (zebrafish) ]

    Gene ID: 393230, updated on 27-Mar-2024

    Summary

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    Official Symbol
    ppp4r1provided by ZNC
    Official Full Name
    protein phosphatase 4, regulatory subunit 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-753
    See related
    AllianceGenome:ZFIN:ZDB-GENE-040426-753
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:55603
    Summary
    Predicted to enable protein phosphatase regulator activity. Predicted to act upstream of or within regulation of catalytic activity and signal transduction. Predicted to be part of protein phosphatase 4 complex. Orthologous to human PPP4R1 (protein phosphatase 4 regulatory subunit 1). [provided by Alliance of Genome Resources, Apr 2022]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See ppp4r1 in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (42054151..42073135, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (42101753..42132575, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) Unplaced Scaffold NW_003336157.1 (7031..12557, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) Unplaced Scaffold NW_003337155.1 (1162..3883, complement)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene protein APCDD1-like Neighboring gene twisted gastrulation BMP signaling modulator 1b Neighboring gene VAMP (vesicle-associated membrane protein)-associated protein A Neighboring gene signal sequence receptor, alpha

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. 4.1Ba is necessary for glutamatergic synapse formation in the sensorimotor circuit of developing zebrafish. Fierro J Jr, et al. PLoS One, 2018. PMID 30286167, Free PMC Article
    2. Chronic reduction in cardiac output induces hypoxic signaling in larval zebrafish even at a time when convective oxygen transport is not required. Kopp R, et al. Physiol Genomics, 2010 Sep. PMID 20571107
    3. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC55603

    General protein information

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    Preferred Names
    serine/threonine-protein phosphatase 4 regulatory subunit 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200260.1 → NP_956554.1  serine/threonine-protein phosphatase 4 regulatory subunit 1

      See identical proteins and their annotated locations for NP_956554.1

      Status: PROVISIONAL

      Source sequence(s)
      BC048878
      UniProtKB/TrEMBL
      Q7ZUL5
      Conserved Domains (3) summary
      pfam15017
      Location:441 → 506
      AF1Q; Drug resistance and apoptosis regulator
      pfam14153
      Location:356 → 430
      Spore_coat_CotO; Spore coat protein CotO
      sd00044
      Location:115 → 140
      HEAT; HEAT repeat [structural motif]

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      42054151..42073135 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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