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    slmapa sarcolemma associated protein a [ Danio rerio (zebrafish) ]

    Gene ID: 572011, updated on 27-Mar-2024

    Summary

    Official Symbol
    slmapaprovided by ZNC
    Official Full Name
    sarcolemma associated protein aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061013-184
    See related
    Ensembl:ENSDARG00000054458 AllianceGenome:ZFIN:ZDB-GENE-061013-184
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fa03e05; fb39b03; wu:fa03e05; wu:fb39b03; zgc:153887
    Summary
    Predicted to be involved in protein localization to plasma membrane; regulation of membrane depolarization during cardiac muscle cell action potential; and regulation of voltage-gated sodium channel activity. Predicted to act upstream of or within muscle contraction. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human SLMAP (sarcolemma associated protein). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See slmapa in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (42305549..42418379, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (42036675..42148441, complement)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103911880 Neighboring gene filamin B, like Neighboring gene DENN/MADD domain containing 6Aa Neighboring gene ADP-ribosylation factor 4b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General protein information

    Preferred Names
    sarcolemma associated protein a; sarcolemmal membrane-associated protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077254.1NP_001070722.1  sarcolemma associated protein a

      See identical proteins and their annotated locations for NP_001070722.1

      Status: PROVISIONAL

      Source sequence(s)
      BC124763
      UniProtKB/TrEMBL
      A0A8M1NB23, Q08BE3
      Related
      ENSDARP00000138370.1, ENSDART00000160704.2
      Conserved Domains (5) summary
      COG1716
      Location:46109
      FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]
      cd00060
      Location:14108
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      TIGR02168
      Location:163793
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam17023
      Location:287475
      DUF5098; Domain of unknown function (DUF5098)
      cl19219
      Location:297367
      DUF342; Protein of unknown function (DUF342)

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      42305549..42418379 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005168063.4XP_005168120.1  sarcolemmal membrane-associated protein isoform X4

      UniProtKB/TrEMBL
      A0A8M2BFI3
      Conserved Domains (4) summary
      COG1716
      Location:46109
      FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]
      cd00060
      Location:14108
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      TIGR02168
      Location:163776
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cl19219
      Location:297367
      DUF342; Protein of unknown function (DUF342)
    2. XM_005168062.4XP_005168119.1  sarcolemmal membrane-associated protein isoform X3

      UniProtKB/TrEMBL
      A0A8M2BFH7
      Conserved Domains (5) summary
      COG1716
      Location:46109
      FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]
      cd00060
      Location:14108
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      TIGR02168
      Location:163793
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam17023
      Location:287475
      DUF5098; Domain of unknown function (DUF5098)
      cl19219
      Location:297367
      DUF342; Protein of unknown function (DUF342)
    3. XM_005168060.4XP_005168117.1  sarcolemmal membrane-associated protein isoform X1

      UniProtKB/TrEMBL
      A0A2R8QQ99, A0A8M2BG26
      Related
      ENSDARP00000155262.1, ENSDART00000191086.1
      Conserved Domains (5) summary
      COG1716
      Location:46109
      FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]
      cd00060
      Location:14108
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      TIGR02168
      Location:163814
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam17023
      Location:287496
      DUF5098; Domain of unknown function (DUF5098)
      cl19219
      Location:297367
      DUF342; Protein of unknown function (DUF342)
    4. XM_005168061.4XP_005168118.1  sarcolemmal membrane-associated protein isoform X2

      UniProtKB/TrEMBL
      A0A8M2BFG9
      Conserved Domains (5) summary
      COG1716
      Location:46109
      FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]
      cd00060
      Location:14108
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      TIGR02168
      Location:163814
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam17023
      Location:287496
      DUF5098; Domain of unknown function (DUF5098)
      cl19219
      Location:297367
      DUF342; Protein of unknown function (DUF342)
    5. XM_005168064.4XP_005168121.1  sarcolemmal membrane-associated protein isoform X5

      UniProtKB/TrEMBL
      A0A8M2BFI9
      Conserved Domains (2) summary
      TIGR02168
      Location:4655
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cl19219
      Location:138208
      DUF342; Protein of unknown function (DUF342)