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    Prss47 serine protease 47 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 680378, updated on 29-Feb-2024

    Summary

    Official Symbol
    Prss47provided by RGD
    Official Full Name
    serine protease 47provided by RGD
    Primary source
    RGD:1592951
    See related
    Ensembl:ENSRNOG00000031461 AllianceGenome:RGD:1592951
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward (RPKM 46.8) See more
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    Genomic context

    See Prss47 in Genome Data Viewer
    Location:
    17p14
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (145606..160046)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (139835..154263)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (2814264..2828350, complement)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene corepressor interacting with RBPJ 1-like Neighboring gene eukaryotic translation elongation factor 1 alpha 1, pseudogene 6 Neighboring gene major facilitator superfamily domain containing 14B Neighboring gene tubulin, alpha 4A, pseudogene 1 Neighboring gene spermatogenesis associated 31 subfamily D, member 1C Neighboring gene spermatogenesis associated 31

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    putative serine protease 47
    Names
    protease, serine, 47

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      145606..160046
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039096357.2XP_038952285.1  putative serine protease 47 isoform X6

      Conserved Domains (1) summary
      cd00190
      Location:83294
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    2. XM_039096358.2XP_038952286.1  putative serine protease 47 isoform X8

      Conserved Domains (1) summary
      cl21584
      Location:83180
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    3. XM_039096354.2XP_038952282.1  putative serine protease 47 isoform X1

      UniProtKB/TrEMBL
      F1M2C8
      Conserved Domains (1) summary
      cd00190
      Location:83342
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    4. XM_039096355.2XP_038952283.1  putative serine protease 47 isoform X2

      UniProtKB/TrEMBL
      F1M2C8
      Conserved Domains (1) summary
      cd00190
      Location:83334
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    5. XM_063276988.1XP_063133058.1  putative serine protease 47 isoform X7

    6. XM_006253500.5XP_006253562.1  putative serine protease 47 isoform X3

      See identical proteins and their annotated locations for XP_006253562.1

      UniProtKB/TrEMBL
      F1M2C8
      Related
      ENSRNOP00000049128.6
      Conserved Domains (2) summary
      smart00020
      Location:82320
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:83323
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    7. XM_039096356.2XP_038952284.1  putative serine protease 47 isoform X4

      UniProtKB/TrEMBL
      A0A8I6AJZ4, A6KQF4
      Related
      ENSRNOP00000093513.1
      Conserved Domains (1) summary
      cd00190
      Location:11270
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    8. XM_063276987.1XP_063133057.1  putative serine protease 47 isoform X5

    9. XM_039096359.2XP_038952287.1  putative serine protease 47 isoform X9

      Conserved Domains (1) summary
      cd00190
      Location:36134
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    RNA

    1. XR_005495637.2 RNA Sequence