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    pdcd2l programmed cell death 2-like [ Danio rerio (zebrafish) ]

    Gene ID: 393192, updated on 27-Mar-2024

    Summary

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    Official Symbol
    pdcd2lprovided by ZNC
    Official Full Name
    programmed cell death 2-likeprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-967
    See related
    Ensembl:ENSDARG00000002754 AllianceGenome:ZFIN:ZDB-GENE-040426-967
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:56288
    Summary
    Acts upstream of or within apoptotic process involved in blood vessel morphogenesis. Predicted to be located in cytoplasm. Orthologous to human PDCD2L (programmed cell death 2 like). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See pdcd2l in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (30442111..30454774)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (29999325..30011715)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene transfer RNA arginine (anticodon ACG) Neighboring gene transfer RNA arginine (anticodon ACG) Neighboring gene transfer RNA arginine (anticodon ACG) Neighboring gene BTG3 associated nuclear protein Neighboring gene zinc finger protein 469

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Zebrafish Model for Functional Screening of Flow-Responsive Genes. Serbanovic-Canic J, et al. Arterioscler Thromb Vasc Biol, 2017 Jan. PMID 27834691, Free PMC Article
    2. Early depletion of primordial germ cells in zebrafish promotes testis formation. Tzung KW, et al. Stem Cell Reports, 2015 Jan 13. PMID 25434820, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC56288

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within apoptotic process involved in blood vessel morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    programmed cell death protein 2-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200223.1 → NP_956517.1  programmed cell death protein 2-like

      See identical proteins and their annotated locations for NP_956517.1

      Status: PROVISIONAL

      Source sequence(s)
      BC046049
      UniProtKB/TrEMBL
      Q7ZV10
      Related
      ENSDARP00000025863.5, ENSDART00000003346.6
      Conserved Domains (1) summary
      pfam04194
      Location:232 → 348
      PDCD2_C; Programmed cell death protein 2, C-terminal putative domain

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      30442111..30454774
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021470458.1 → XP_021326133.1  programmed cell death protein 2-like isoform X1

      UniProtKB/TrEMBL
      A0A8M9PMM7
      Conserved Domains (1) summary
      pfam04194
      Location:114 → 230
      PDCD2_C; Programmed cell death protein 2, C-terminal putative domain

    2. XM_021470459.1 → XP_021326134.1  programmed cell death protein 2-like isoform X1

      UniProtKB/TrEMBL
      A0A8M9PMM7
      Conserved Domains (1) summary
      pfam04194
      Location:114 → 230
      PDCD2_C; Programmed cell death protein 2, C-terminal putative domain

    3. XM_021470460.1 → XP_021326135.1  programmed cell death protein 2-like isoform X1

      UniProtKB/TrEMBL
      A0A8M9PMM7
      Conserved Domains (1) summary
      pfam04194
      Location:114 → 230
      PDCD2_C; Programmed cell death protein 2, C-terminal putative domain
    Nucleotide Protein Strain
    Heading Accession and Version

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