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    SPIDR scaffold protein involved in DNA repair [ Canis lupus familiaris (dog) ]

    Gene ID: 478694, updated on 5-Mar-2024

    Summary

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    Official Symbol
    SPIDRprovided by VGNC
    Official Full Name
    scaffold protein involved in DNA repairprovided by VGNC
    Primary source
    VGNC:VGNC:46741
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See SPIDR in Genome Data Viewer
    Location:
    chromosome: 35
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 35 NC_051839.1 (28419..463757, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 35 NC_006617.4 (90608..526254, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 35 NC_049256.1 (1366967..1802342, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 35 NC_049295.1 (13433..448429, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 35 NC_049776.1 (31778..466957, complement)

    Chromosome 35 - NC_051839.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119867633 Neighboring gene CCAAT enhancer binding protein delta Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC119867632 Neighboring gene uncharacterized LOC111094030 Neighboring gene RING finger protein 121-like Neighboring gene glycine-rich protein 5-like Neighboring gene uncharacterized LOC119867746

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in double-strand break repair via homologous recombination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of establishment of protein localization to chromosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nuclear chromosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA repair-scaffolding protein
    Names
    scaffolding protein involved in DNA repair

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051839.1 Reference ROS_Cfam_1.0

      Range
      28419..463757 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038446192.1 → XP_038302120.1  DNA repair-scaffolding protein isoform X4

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:6 → 387
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:538 → 979
      DUF4503; Domain of unknown function (DUF4503)

    2. XM_038446190.1 → XP_038302118.1  DNA repair-scaffolding protein isoform X2

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 988
      DUF4503; Domain of unknown function (DUF4503)

    3. XM_038446191.1 → XP_038302119.1  DNA repair-scaffolding protein isoform X3

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 983
      DUF4503; Domain of unknown function (DUF4503)

    4. XM_038446194.1 → XP_038302122.1  DNA repair-scaffolding protein isoform X6

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 964
      DUF4503; Domain of unknown function (DUF4503)

    5. XM_038446189.1 → XP_038302117.1  DNA repair-scaffolding protein isoform X1

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 989
      DUF4503; Domain of unknown function (DUF4503)

    6. XM_038446193.1 → XP_038302121.1  DNA repair-scaffolding protein isoform X5

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 965
      DUF4503; Domain of unknown function (DUF4503)

    7. XM_038446197.1 → XP_038302125.1  DNA repair-scaffolding protein isoform X9

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 949
      DUF4503; Domain of unknown function (DUF4503)

    8. XM_038446199.1 → XP_038302127.1  DNA repair-scaffolding protein isoform X10

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 924
      DUF4503; Domain of unknown function (DUF4503)

    9. XM_038446196.1 → XP_038302124.1  DNA repair-scaffolding protein isoform X8

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 922
      DUF4503; Domain of unknown function (DUF4503)

    10. XM_038446195.1 → XP_038302123.1  DNA repair-scaffolding protein isoform X7

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 928
      DUF4503; Domain of unknown function (DUF4503)

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049295.1 Alternate UMICH_Zoey_3.1

      Range
      13433..448429 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038520367.1 → XP_038376295.1  DNA repair-scaffolding protein isoform X4

      Conserved Domains (2) summary
      pfam14950
      Location:6 → 387
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:538 → 979
      DUF4503; Domain of unknown function (DUF4503)

    2. XM_038520365.1 → XP_038376293.1  DNA repair-scaffolding protein isoform X2

      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 988
      DUF4503; Domain of unknown function (DUF4503)

    3. XM_038520366.1 → XP_038376294.1  DNA repair-scaffolding protein isoform X3

      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 983
      DUF4503; Domain of unknown function (DUF4503)

    4. XM_038520364.1 → XP_038376292.1  DNA repair-scaffolding protein isoform X1

      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 989
      DUF4503; Domain of unknown function (DUF4503)

    5. XM_038520369.1 → XP_038376297.1  DNA repair-scaffolding protein isoform X6

      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 964
      DUF4503; Domain of unknown function (DUF4503)

    6. XM_038520368.1 → XP_038376296.1  DNA repair-scaffolding protein isoform X5

      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 965
      DUF4503; Domain of unknown function (DUF4503)

    7. XM_038520372.1 → XP_038376300.1  DNA repair-scaffolding protein isoform X9

      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 949
      DUF4503; Domain of unknown function (DUF4503)

    8. XM_038520373.1 → XP_038376301.1  DNA repair-scaffolding protein isoform X10

      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 924
      DUF4503; Domain of unknown function (DUF4503)

    9. XM_038520371.1 → XP_038376299.1  DNA repair-scaffolding protein isoform X8

      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 922
      DUF4503; Domain of unknown function (DUF4503)

    10. XM_038520370.1 → XP_038376298.1  DNA repair-scaffolding protein isoform X7

      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 928
      DUF4503; Domain of unknown function (DUF4503)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049776.1 Alternate UNSW_CanFamBas_1.0

      Range
      31778..466957 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038648405.1 → XP_038504333.1  DNA repair-scaffolding protein isoform X4

      Conserved Domains (2) summary
      pfam14950
      Location:6 → 387
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:538 → 979
      DUF4503; Domain of unknown function (DUF4503)

    2. XM_038648403.1 → XP_038504331.1  DNA repair-scaffolding protein isoform X2

      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 988
      DUF4503; Domain of unknown function (DUF4503)

    3. XM_038648404.1 → XP_038504332.1  DNA repair-scaffolding protein isoform X3

      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 983
      DUF4503; Domain of unknown function (DUF4503)

    4. XM_038648402.1 → XP_038504330.1  DNA repair-scaffolding protein isoform X1

      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 989
      DUF4503; Domain of unknown function (DUF4503)

    5. XM_038648407.1 → XP_038504335.1  DNA repair-scaffolding protein isoform X6

      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 964
      DUF4503; Domain of unknown function (DUF4503)

    6. XM_038648406.1 → XP_038504334.1  DNA repair-scaffolding protein isoform X5

      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 965
      DUF4503; Domain of unknown function (DUF4503)

    7. XM_038648410.1 → XP_038504338.1  DNA repair-scaffolding protein isoform X9

      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 949
      DUF4503; Domain of unknown function (DUF4503)

    8. XM_038648411.1 → XP_038504339.1  DNA repair-scaffolding protein isoform X10

      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 924
      DUF4503; Domain of unknown function (DUF4503)

    9. XM_038648409.1 → XP_038504337.1  DNA repair-scaffolding protein isoform X8

      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 922
      DUF4503; Domain of unknown function (DUF4503)

    10. XM_038648408.1 → XP_038504336.1  DNA repair-scaffolding protein isoform X7

      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 928
      DUF4503; Domain of unknown function (DUF4503)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049256.1 Alternate UU_Cfam_GSD_1.0

      Range
      1366967..1802342 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038583990.1 → XP_038439918.1  DNA repair-scaffolding protein isoform X4

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:6 → 387
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:538 → 979
      DUF4503; Domain of unknown function (DUF4503)

    2. XM_038583988.1 → XP_038439916.1  DNA repair-scaffolding protein isoform X2

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 988
      DUF4503; Domain of unknown function (DUF4503)

    3. XM_038583989.1 → XP_038439917.1  DNA repair-scaffolding protein isoform X3

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 983
      DUF4503; Domain of unknown function (DUF4503)

    4. XM_038583987.1 → XP_038439915.1  DNA repair-scaffolding protein isoform X1

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 989
      DUF4503; Domain of unknown function (DUF4503)

    5. XM_038583992.1 → XP_038439920.1  DNA repair-scaffolding protein isoform X6

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 964
      DUF4503; Domain of unknown function (DUF4503)

    6. XM_038583991.1 → XP_038439919.1  DNA repair-scaffolding protein isoform X5

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 965
      DUF4503; Domain of unknown function (DUF4503)

    7. XM_038583995.1 → XP_038439923.1  DNA repair-scaffolding protein isoform X9

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 949
      DUF4503; Domain of unknown function (DUF4503)

    8. XM_038583996.1 → XP_038439924.1  DNA repair-scaffolding protein isoform X10

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 924
      DUF4503; Domain of unknown function (DUF4503)

    9. XM_038583994.1 → XP_038439922.1  DNA repair-scaffolding protein isoform X8

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 922
      DUF4503; Domain of unknown function (DUF4503)

    10. XM_038583993.1 → XP_038439921.1  DNA repair-scaffolding protein isoform X7

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 928
      DUF4503; Domain of unknown function (DUF4503)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006617.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      90608..526254 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038463160.1 → XP_038319088.1  DNA repair-scaffolding protein isoform X4

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:6 → 387
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:538 → 979
      DUF4503; Domain of unknown function (DUF4503)

    2. XM_038463158.1 → XP_038319086.1  DNA repair-scaffolding protein isoform X2

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 988
      DUF4503; Domain of unknown function (DUF4503)

    3. XM_038463159.1 → XP_038319087.1  DNA repair-scaffolding protein isoform X3

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 983
      DUF4503; Domain of unknown function (DUF4503)

    4. XM_038463157.1 → XP_038319085.1  DNA repair-scaffolding protein isoform X1

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 989
      DUF4503; Domain of unknown function (DUF4503)

    5. XM_038463162.1 → XP_038319090.1  DNA repair-scaffolding protein isoform X6

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 964
      DUF4503; Domain of unknown function (DUF4503)

    6. XM_038463161.1 → XP_038319089.1  DNA repair-scaffolding protein isoform X5

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 965
      DUF4503; Domain of unknown function (DUF4503)

    7. XM_022414507.2 → XP_022270215.1  DNA repair-scaffolding protein isoform X9

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 949
      DUF4503; Domain of unknown function (DUF4503)

    8. XM_022414511.2 → XP_022270219.1  DNA repair-scaffolding protein isoform X10

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 924
      DUF4503; Domain of unknown function (DUF4503)

    9. XM_038463164.1 → XP_038319092.1  DNA repair-scaffolding protein isoform X8

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 922
      DUF4503; Domain of unknown function (DUF4503)

    10. XM_038463163.1 → XP_038319091.1  DNA repair-scaffolding protein isoform X7

      UniProtKB/TrEMBL
      A0A8C0JK81
      Conserved Domains (2) summary
      pfam14950
      Location:16 → 397
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:548 → 928
      DUF4503; Domain of unknown function (DUF4503)
    Nucleotide Protein
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